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Neurotensin Receptors(神经降压素受体)

Neurotensin receptors are transmembrane receptors that bind the neurotransmitter neurotensin. Two of the receptors encoded by the NTSR1 and NTSR2 genes contain seven transmembrane helices and are G protein coupled. The third receptor has a single transmembrane domain and is encoded by the SORT1 gene. Neurotensin (NTS) is a 13-amino-acid peptide that functions as both a neurotransmitter and a hormone through the activation of the neurotensin receptor NTSR1, a G-protein-coupled receptor (GPCR). In the brain, NTS modulates the activity of dopaminergic systems, opioid-independent analgesia, and the inhibition of food intake; in the gut, NTS regulates a range of digestive processes.

  1. Cat.No. 产品名称 Information
  2. GC67786 THX-B
  3. GC61800 JMV 449 acetate
  4. GC61739 SORT-PGRN interaction inhibitor 1
  5. GC50164 NTRC 824 NTRC 824 (Compound 5) 是一种有效的、选择性的神经降压素样非肽类神经降压素受体 2 (NTS2) 拮抗剂,IC50 为 38 nM,Ki 为 202 nM。
  6. GC50096 TC NTR1 17 Selective NTS1 partial agonist
  7. GC38847 SBI-553 A β-arrestin-biased positive allosteric modulator of NTSR1
  8. GC38586 AF40431
  9. GC36729 Neurotensin(8-13) A neuropeptide
  10. GC19441 Levocabastine (hydrochloride) A histamine H1 receptor antagonist
  11. GC19023 AF38469 An inhibitor of sortilin
  12. GC18216 ML314 An NTS1 agonist
  13. GC13242 SR 48692 An allosteric antagonist of NTS1
  14. GC16683 SR 142948 A neurotensin receptor antagonist
  15. GC11333 Xenin 8 Xenin 8 是一种 C 末端八肽,是 Xenin 的生物活性片段。
  16. GC17784 JMV 449 JMV 449 是一种有效的神经降压素受体激动剂。
  17. GC14971 Kinetensin (human) A peptide
  18. GC16357 Neurotensin A neuropeptide with diverse biological activities

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