Neurotensin Receptors(神经降压素受体)
Neurotensin receptors are transmembrane receptors that bind the neurotransmitter neurotensin. Two of the receptors encoded by the NTSR1 and NTSR2 genes contain seven transmembrane helices and are G protein coupled. The third receptor has a single transmembrane domain and is encoded by the SORT1 gene. Neurotensin (NTS) is a 13-amino-acid peptide that functions as both a neurotransmitter and a hormone through the activation of the neurotensin receptor NTSR1, a G-protein-coupled receptor (GPCR). In the brain, NTS modulates the activity of dopaminergic systems, opioid-independent analgesia, and the inhibition of food intake; in the gut, NTS regulates a range of digestive processes.
- Cat.No. 产品名称 Information
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GC67786
THX-B
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GC61800
JMV 449 acetate
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GC61739
SORT-PGRN interaction inhibitor 1
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GC50164
NTRC 824
NTRC 824 (Compound 5) 是一种有效的、选择性的神经降压素样非肽类神经降压素受体 2 (NTS2) 拮抗剂,IC50 为 38 nM,Ki 为 202 nM。
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GC50096
TC NTR1 17
Selective NTS1 partial agonist
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GC38847
SBI-553
A β-arrestin-biased positive allosteric modulator of NTSR1
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GC38586
AF40431
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GC36729
Neurotensin(8-13)
A neuropeptide
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GC19441
Levocabastine (hydrochloride)
A histamine H1 receptor antagonist
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GC19023
AF38469
An inhibitor of sortilin
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GC18216
ML314
An NTS1 agonist
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GC13242
SR 48692
An allosteric antagonist of NTS1
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GC16683
SR 142948
A neurotensin receptor antagonist
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GC11333
Xenin 8
Xenin 8 是一种 C 末端八肽,是 Xenin 的生物活性片段。
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GC17784
JMV 449
JMV 449 是一种有效的神经降压素受体激动剂。
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GC14971
Kinetensin (human)
A peptide
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GC16357
Neurotensin
A neuropeptide with diverse biological activities