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Home >> Signaling Pathways >> GPCR/G protein >> OX Receptor

OX Receptor(OX 受体)

OX receptor (orexin receptor) is a G-protein coupled receptor that is involved in the regulation of feeding behaviour.

  1. Cat.No. 产品名称 Information
  2. GC67957 Orexin A (human, rat, mouse) (acetate)
  3. GC67929 Orexin 2 Receptor Agonist 2
  4. GC65550 Danavorexton
  5. GC65382 Orexin receptor antagonist 5
  6. GC64826 Vornorexant
  7. GC64021 Orexin B, rat, mouse TFA
  8. GC63415 JNJ-54717793
  9. GC61770 Orexin receptor antagonist 2
  10. GC50559 YNT 185 YNT 185 是一种非肽、选择性食欲素 2 型受体 (OX2R) 激动剂，对于 OX2R 和 OX1R，EC50 分别为 0.028 和 2.75 μ；M。
  11. GC50142 ACT 462206 ACT 462206 是一种口服有效的 Orexin 1/Orexin 2 双重受体拮抗剂，IC50 分别为 60 nM (Orexin 1) 和 11 nM (Orexin 2)。
  12. GC38352 Orexin A (human, rat, mouse) (TFA)
  13. GC37623 Seltorexant
  14. GC36812 Orexin B, human TFA
  15. GC30941 Nemorexant (ACT-541468)
  16. GC30832 GSK1059865
  17. GC30829 IPSU An orexin receptor 2 antagonist
  18. GC19323 SB-649868 A dual orexin receptor antagonist
  19. GC19272 Orexin 2 Receptor Agonist An orexin 2 receptor agonist
  20. GC19250 MK-3697 An orexin receptor 2 antagonist
  21. GC19249 MK-1064 An orexin 2 receptor antagonist
  22. GC19220 Lemborexant

    Lemborexant (E2006) is an oral active diorexin receptor antagonist (DORA) and has been approved by the US Food and Drug Administration for the treatment of insomnia.
  23. GC12242 MK 6096 A dual orexin receptor antagonist
  24. GC16336 ACT 335827 ACT 335827 是一种选择性、口服活性、脑渗透性食欲素 1 型受体拮抗剂。
  25. GC13741 EMPA An OX2R receptor antagonist
  26. GC14809 JNJ 10397049 An oxrexin 2 receptor antagonist
  27. GC10549 TCS OX2 29 A selective orexin receptor 2 antagonist
  28. GC11818 OXA (17-33) OXA (17-33) 是一种有效的选择性 orexin-1 受体 (OX1) 激动剂。
  29. GC17992 [Ala11,D-Leu15]-Orexin B [Ala11,D-Leu15]-Orexin B 是一种有效的选择性orexin-2 受体 (OX2) 激动剂。
  30. GC16745 Orexin B (mouse) Orexin B (mouse) (Rat orexin B) 是 Orexin 受体的内源性激动剂，对 OX1 和 OX2 的 Kis 分别为 420 和 36 nM。
  31. GC14887 Orexin B (human) Orexin B (human) 是 Orexin 受体的内源性激动剂，对 OX1 和 OX2 的 Kis 分别为 420 和 36 nM。
  32. GC15034 SB-334867 free base An orexin 1 receptor antagonist
  33. GC15317 SB408124 A potent orexin 1 receptor antagonist
  34. GC17807 TCS 1102 A dual orexin receptor antagonist
  35. GC13539 SB-334867 An orexin 1 receptor antagonist
  36. GC10050 Almorexant hydrochloride An orexin 1 and orexin 2 receptor antagonist
  37. GC10717 Almorexant Almorexant (ACT 078573) 是一种具有口服活性、强效和竞争性的双重食欲素受体拮抗剂，Kd 值分别为 1.3 nM (OX1) 和 0.17 nM (OX2)。
  38. GC15534 SB-674042 A potent and selective orexin 1 receptor antagonist
  39. GC16540 SB-408124 Hydrochloride A potent orexin 1 receptor antagonist

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