S1P receptor(S1P受体)

S1P (sphinogosine-1-phosphate) receptor is a G-protein coupled receptor that involved in regulation of cells proliferation, survival, motility and adhesion etc.

Products for S1P receptor

Cat.No. 产品名称 Information
GC50275 Ex 26
S1P1-IN-Ex26
Ex 26 (S1P1-IN-Ex 26) 是一种有效的选择性 1-磷酸鞘氨醇受体 1 (S1P1) 拮抗剂 (IC50\u003d0.93 nM)。
GC42664 A-971432 A sphingosine-1-phosphate receptor 5 (S1P₅) agonist
GC16660 Ponesimod
ACT-128800
A potent S1P₁ receptor agonist
GC14360 Ozanimod (RPC1063)
奥扎莫德; RPC-1063
An S1P₁ and S1P₅ agonist
GC16701 SKI II
鞘氨醇激酶抑制剂
An SPHK1 inhibitor
GC17201 BAF312 (Siponimod)
辛波莫德; BAF-312
An S1P₁ and S1P₅ receptor agonist receptor modulator
GC14807 Fingolimod (FTY720) HCl
盐酸芬戈莫德; FTY720

Fingolimod (FTY720), an immunosuppressant agent, usually used in the treatment of multiple sclerosis, also has anticancer actions and can act as an HDACi (Histone deacetylase inhibitors)[1].
GC11917 PF-543
(2R)-1-[[4-[[3-甲基-5-[(苯磺酰基)甲基]苯氧基]甲基]苯基]甲基]-2-吡咯烷甲醇,PF543; PF 543

PF-543是一种新型的细胞渗透性鞘氨醇激酶（SphK1）抑制剂，其IC₅₀值为3.6 nM，K_i值为3.6 nM。