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Home >> Signaling Pathways >> GPCR/G protein >> Chemokine Receptors

Chemokine Receptors(趋化因子受体)

  1. Cat.No. 产品名称 Information
  2. GC50742 Chemerin-9, Mouse Chemokine-like receptor 1 (CMKLR1) agonist (EC50 = 42 nM)
  3. GC50711 ML 339 Potent and selective hCXCR6 antagonist (IC50 = 140 nM); 100-fold less active at the murine CXCR6 receptor (IC50 = 18 μM)
  4. GC50655 AZ 10397767 Potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin-induced NF-κB activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells
  5. GC50351 KRH 3955 hydrochloride Highly potent CXCR4 antagonist; inhibits HIV-1 replication
  6. GC50229 VUF 11222 High affinity non-peptide CXCR3 agonist
  7. GC35673 Chemerin-9 149-157
  8. GC13458 SB 265610 A selective CXCR2 inverse agonist
  9. GC14317 BMS CCR2 22 BMS CCR2 22 是一种有效、特异性和高亲和力的 CC 型趋化因子受体 2 (CCR2) 拮抗剂，具有出色的结合亲和力（结合 IC50 为 5.1 nM）和有效的功能拮抗作用（钙通量 IC50 为 18 nM，趋化性 IC50 为 1 nM） 。
  10. GC14554 J 113863 J 113863 是一种有效的选择性 CCR1 (CD18) 拮抗剂，对人和小鼠 CCR1 受体的 IC50 值分别为 0.9 nM 和 5.8 nM。
  11. GC14551 VUF 11207 fumarate ACKR3 (CXCR7) chemokine receptor agonist
  12. GC10432 IT1t dihydrochloride A CXCR4 antagonist
  13. GC11946 SB 297006 A selective antagonist of CCR3
  14. GC17834 Teijin compound 1 A CCR2b antagonist
  15. GC15183 SB 328437 A CCR3 antagonist
  16. GC11161 C 021 dihydrochloride C 021 dihydrochloride 是一种有效的 CC 趋化因子受体 4 (CCR4) 拮抗剂。
  17. GC14519 BX 471 A selective CCR1 antagonist
  18. GC13299 BX 513 hydrochloride Selective CCR1 antagonist
  19. GC15045 (±)-AMG 487 A CXCR3 antagonist
  20. GC11316 UCB 35625 chemokine CCR1 and CCR3 receptor antagonist
  21. GC11327 ZK 756326 A non-peptide agonist of CCR8
  22. GC11026 RS 102895 hydrochloride A chemokine receptor CCR2 antagonist
  23. GC13360 CTCE 9908 CTCE 9908 是一种有效的选择性 CXCR4 拮抗剂。 CTCE 9908 在表达 CXCR4 的卵巢癌细胞中诱导有丝分裂灾难、细胞毒性并抑制迁移。
  24. GC17040 DAPTA A CCR5 receptor antagonist
  25. GC13774 FC 131 An inhibitor of CXCR4 activation
  26. GC17122 TC 14012

    TC14012, a serum-stable derivative of T140, is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.

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