Chemokine Receptors(趋化因子受体)
- Cat.No. 产品名称 Information
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GC50742
Chemerin-9, Mouse
Chemokine-like receptor 1 (CMKLR1) agonist (EC50 = 42 nM)
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GC50711
ML 339
Potent and selective hCXCR6 antagonist (IC50 = 140 nM); 100-fold less active at the murine CXCR6 receptor (IC50 = 18 μM)
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GC50655
AZ 10397767
Potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin-induced NF-κB activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells
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GC50351
KRH 3955 hydrochloride
Highly potent CXCR4 antagonist; inhibits HIV-1 replication
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GC50229
VUF 11222
High affinity non-peptide CXCR3 agonist
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GC35673
Chemerin-9 149-157
Chemerin-9 (149-157),是位于chemerin-9 149-157位的多肽 (YFPGQFAFS(157),与加工后的chemerin 的 C端相对应,保留了全蛋白绝大部分活性,与对chemerinR的激动作用有关。
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GC13458
SB 265610
A selective CXCR2 inverse agonist
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GC14317
BMS CCR2 22
BMS CCR2 22 是一种有效、特异性和高亲和力的 CC 型趋化因子受体 2 (CCR2) 拮抗剂,具有出色的结合亲和力(结合 IC50 为 5.1 nM)和有效的功能拮抗作用(钙通量 IC50 为 18 nM,趋化性 IC50 为 1 nM) 。
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GC14554
J 113863
J 113863 是一种有效的选择性 CCR1 (CD18) 拮抗剂,对人和小鼠 CCR1 受体的 IC50 值分别为 0.9 nM 和 5.8 nM。
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GC14551
VUF 11207 fumarate
ACKR3 (CXCR7) chemokine receptor agonist
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GC10432
IT1t dihydrochloride
A CXCR4 antagonist
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GC11946
SB 297006
A selective antagonist of CCR3
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GC17834
Teijin compound 1
A CCR2b antagonist
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GC15183
SB 328437
A CCR3 antagonist
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GC11161
C 021 dihydrochloride
C 021 dihydrochloride 是一种有效的 CC 趋化因子受体 4 (CCR4) 拮抗剂。
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GC14519
BX 471
A selective CCR1 antagonist
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GC13299
BX 513 hydrochloride
Selective CCR1 antagonist
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GC15045
(±)-AMG 487
A CXCR3 antagonist
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GC11316
UCB 35625
chemokine CCR1 and CCR3 receptor antagonist
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GC11327
ZK 756326
A non-peptide agonist of CCR8
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GC11026
RS 102895 hydrochloride
A chemokine receptor CCR2 antagonist
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GC13360
CTCE 9908
CTCE 9908 是一种有效的选择性 CXCR4 拮抗剂。 CTCE 9908 在表达 CXCR4 的卵巢癌细胞中诱导有丝分裂灾难、细胞毒性并抑制迁移。
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GC17040
DAPTA
A CCR5 receptor antagonist
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GC13774
FC 131
An inhibitor of CXCR4 activation
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GC17122
TC 14012
TC14012, a serum-stable derivative of T140, is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.