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Prostaglandin Receptor

Prostaglandin receptors are a group of g-protein coupled receptor that exhibited a variety of functions in regulation of blood pressure and renal function; smooth muscle contraction; inhibition of plate aggregation; immune response etc.

  1. Cat.No. Product Name Information
  2. GC16838 (±)-Cloprostenol sodium salt prostaglandin F2α (PGF2α) analog,FP receptor agonist
  3. GC30743 (+)-Cloprostenol (D-Cloprostenol) (+)-Cloprostenol是前列腺素F2α的类似物,为选择性的prostaglandinreceptor激动剂。
  4. GC45259 (+)-Cloprostenol (sodium salt) (+)-Cloprostenol (sodium salt) is a more water soluble, crystalline form of (+)-cloprostenol.
  5. GC12750 (+)-Fluprostenol Prostaglandin F2α (FP) receptor agonist
  6. GC30561 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 2-(E-2-decenoylamino)ethyl2-(cyclohexylethyl)sulfide是一种由压力诱发的溃疡和低毒性抑制剂,可以在压力引起的溃疡大鼠中,维持磷脂酶A2(phospholipaseA2)和前列腺素E2(prostaglandinE2)的含量水平。
  7. GC17719 5-trans U-46619 Prostaglandin E synthase inhibitor
  8. GC10623 ACS 67 analog of latanoprost (free acid),prostaglandin (PG) analog
  9. GC30572 Aganepag (AGN 210937) Aganepag是一种前列腺素类EP2受体激动剂,EC50值为0.19nM,对EP4无作用。Aganepag可用于伤口愈合、伤疤减少以及皱纹的预防和治疗等。
  10. GC31972 AGN 210676 (Simenepag) AGN210676是一种有效的选择性前列腺素EP2激动剂,EC50为5nM。详细信息请参考专利文献US20070203222A1中的化合物example23。
  11. GC40750 Agnuside Agnuside is an iridoid glycoside originally isolated from V.
  12. GC17224 AH 23848 (calcium salt) dual antagonist of TP1 and EP4 receptors
  13. GC14879 AH 6809 EP and DP receptor antagonist
  14. GC16895 AL 8810 Antagonist of prostaglandin F2α (FP) receptor.
  15. GC16566 AL 8810 isopropyl ester lipid soluble, esterified prodrug form of AL 8810, a FP receptor antagonist
  16. GC32558 Aligeron Aligeron是一种非选择性的prostaglandin(PG)拮抗剂,具有舒张血管的作用。
  17. GC17347 Alprostadil vasodilator
  18. GC31718 AM211 (AM211 free acid) AM211是一种有效的,选择性的,可口服的前列腺素受体(DP2)拮抗剂,对人,小鼠,豚鼠和大鼠的DP2的IC50值分别为4.9nM,7.8nM,4.9nM,10.4nM。
  19. GC50240 AMG 853 Potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist
  20. GC31830 AMG-009 AMG-009是prostaglandinD2的有效拮抗剂,对CRTH2和DP受体的IC50值分别为3nM和12nM。
  21. GC31702 Asapiprant (S-555739) Asapiprant是一个强效且有选择性的DP1受体拮抗剂,其Ki值为0.44nM。

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