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Calcimimetic Agent(拟钙剂)

Calcimimetic agent is allosteric activator of the CaSR (calcium-sensing receptor) in the parathyroid tissue. It reduces the threshold of the CaSR activation through extracellular calcium ion and attenuate parathyroid hormone secretion.

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  2. GC16708 Cinacalcet HCl Cinacalcet HCl (AMG-073 hydrochloride) 是一种具有口服活性的 Ca 受体 (CaR) 变构激动剂,用于心血管疾病的治疗。
  3. GC13518 Cinacalcet Cinacalcet (AMG 073) 是一种具有口服活性的 Ca 受体 (CaR) 变构激动剂,用于心血管疾病的治疗。

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