Akt - PI3K/Akt/mTOR Signaling - Signaling Pathways

Cat.No. 产品名称 Information

GC25638 Miransertib (ARQ 092) HCl Miransertib (ARQ 092) HCl is a novel, orally bioavailable and selective AKT pathway inhibitor exhibiting a manageable safety profile among patients with advanced solid tumors.

GC67700 AKT Kinase Inhibitor hydrochloride

GC65559 INY-03-041

GC65466 MS170

GC65442 Musk ketone

GC65367 Borussertib Borussertib is a covalent-allosteric inhibitor of protein kinase Akt with an IC50 of 0.8 nM and a Ki of 2.2 nM for WT Akt.

GC65143 MKC-1

GC64936 TD52 dihydrochloride A derivative of erlotinib

GC64670 24-Methylenecycloartanyl ferulate

GC64377 Batatasin III

GC64231 Vevorisertib trihydrochloride

GC64223 Sophocarpine monohydrate An alkaloid with diverse biological activities

GC63539 CCT128930 hydrochloride An inhibitor of Akt2

GC63210 TAS-117

GC49440 ML-9 A PKB/Akt inhibitor

GC62630 TAS-117 hydrochloride

GC62342 TASP0415914

GC62191 TD52 A derivative of erlotinib

GC62190 AKT-IN-6

GC62122 (E)-Akt inhibitor-IV (E)-Akt inhibitor-IV is a PI3K-Akt inhibitor, with potent cytotoxic.

GC60262 N-Feruloyloctopamine

GC39266 Hematein Hematein inhibits casein kinase II activity in a selective, dose-dependent and ATP non-competitive manner in vitro, with IC50 of 0.55 μM in the presence of 10 μM ATP.

GC38679 Urolithin B A metabolite of ellagic acid

GC38609 Rotundic acid Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.RA induces cell cycle arrest, DNA damage, and apoptosis by modulating the AKT/mTOR and MAPK pathways.

GC38606 Glaucocalyxin A Glaucocalyxin A is a biologically active ent-kauranoid diterpenoid isolated from Rabdosia japonica var. glaucocalyx with antitumor and anti-inflammatory activity. Glaucocalyxin A induces G2/M cell cycle arrest and apoptosis through the PI3K/Akt pathway in human bladder cancer cells.

GC38419 Cyclovirobuxine D An alkaloid with diverse biological activities

GC38236 Esculetin A coumarin with diverse actions

GC38170 Phellodendrine An alkaloid with diverse biological activities

GC38088 Hederacolchiside A1

GC37955 YS-49 monohydrate An inhibitor of platelet aggregation

GC37954 YS-49 An inhibitor of platelet aggregation

GC37859 Uprosertib hydrochloride A selective Akt inhibitor

GC36855 Paris saponin VII Chonglou Saponin VII (Dioscinin, Polyphyllin-VII, Paris saponin-VII), a kind of steroidal saponins from Chonglou (Rhizoma Paridis Chonglou), inhibits EMT and reduces the invasion of ovarian cancer cells via the GSK-3β/β-catenin signaling pathway.