Guanylate Cyclase (鸟苷酸环化酶)

GC (guanylyl cyclaese) converts GTP into cGMP and pyrophosphate. sGC (soluble GC) is a nitric oxide receptor and pGC (transmembrance GC) is a natriiuritic peptide receptor. Its major functions include cell hyperplasia,hypertrophy, cell differentiation and tumor progression etc.

Cat.No. 产品名称 Information
GC34045 (4-Acetamidocyclohexyl) nitrate (BM121307)
GC64490 (Rac)-MGV354
GC11361 Ataciguat An activator of sGC
GC10192 BAY 41-2272 An activator of soluble guanylate cyclase
GC11426 BAY 41-8543 Stimulator of soluble guanylate cyclase
GC65051 BAY 60-2770
GC10962 Cinaciguat An activator of sGC
GC19459 Cinaciguat hydrochloride An activator of sGC
GC61604 Guanylin(human) TFA
GC30016 Linaclotide A peptide agonist of the guanylate cyclase C receptor
GC13857 LY83583
A soluble guanylate cyclase inhibitor
GC30051 Methylene Blue (Basic Blue 9)
Methylene Blue (Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015) is used as a dye in chromoendoscopy. It Inhibits tau filament formation with IC50 of 1.9μM. Also it inhibits soluble guanylyl cyclase.
GC39603 Methylene blue trihydrate
GC62616 MGV354
GC63294 MM 419447
GC32493 Nelociguat (BAY60-4552) A stimulator of soluble guanylate cyclase and an active metabolite of riociguat
GC16975 NS 2028 A specific inhibitor of soluble guanylyl cyclase
GC36801 Olinciguat
GC33898 Plecanatide acetate A peptide agonist of the guanylate cyclase C receptor
GC65449 Praliciguat
GC12887 Riociguat A stimulator of soluble guanylate cyclase
GC65192 Runcaciguat
GC32472 Vericiguat (BAY1021189) A stimulator of soluble guanylyl cyclase
GC16406 YC 1 An activator of soluble guanylyl cyclase
GC65182 Zagociguat