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Macrophage Migration Inhibitory Factor(巨噬细胞迁移抑制因子)

  1. Cat.No. 产品名称 Information
  2. GC48920 β-Carboline-1-carboxylic Acid An alkaloid with diverse biological activities
  3. GC45270 (±)10(11)-EDP Ethanolamide (±)10(11)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 0.43 and 22.5 nM for CB1 and CB2 receptors, respectively).
  4. GC41648 (±)13(14)-DiHDPA (±)13(14)-DiHDPA is a metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases.
  5. GC41653 (±)16(17)-DiHDPA (±)16(17)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid.
  6. GC41655 (±)19(20)-EDP Ethanolamide (±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively).
  7. GC45266 (+)-Macrosphelide A (+)-Macrosphelide A 是一种大环内酯类抗生素。
  8. GC40444 (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic Acid (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid is a stable isomer of 15(S)-HETE, a major arachidonic acid metabolite from the 15-lipoxygenase pathway.
  9. GC41220 13(S)-HODE methyl ester 13(S)-hydroxyoctadecadienoic acid (13(S)-HODE) is a 15-lipoxygenase metabolite of linoleic acid produced in endothelial cells, leukocytes, and tumor cells.
  10. GC46733 7,12-Dimethylbenz[a]anthracene 7,12-二甲基苯并[a]蒽作为多环芳烃 (PAH) 具有致癌活性。 7,12-二甲基苯并[a]蒽用于在各种啮齿动物模型中诱导肿瘤形成。
  11. GC48486 AAA A GPR75 antagonist
  12. GC46821 Ajoene Ajoene 是一种大蒜衍生的化合物,是一种抗血栓和抗真菌剂。
  13. GC42951 BMP-22 BMP-22 is an inhibitor of autotaxin (IC50 = 170 nM).
  14. GC42975 BRD32048 BRD32048 是 ETV1 的直接结合剂,KD 为 17.1 μM。 BRD32048 调节 ETV1 介导的转录活性和 ETV1 驱动的癌细胞的侵袭。 BRD32048 抑制 ETV1 乙酰化并促进其降解。 BRD32048 是最佳候选 ETV1 干扰素。
  15. GC48433 BX-320 BX-320 是一种选择性的、ATP 竞争性的、口服活性的直接 PDK1 抑制剂,在直接激酶测定中其 IC50 为 30 nM。 BX-320 还诱导细胞凋亡。抗癌作用。
  16. GC43042 C17 Lactosylceramide (d18:1/17:0) C17 Lactosylceramide is a naturally occurring sphingolipid that has been found in human brain metastases of lung adenocarcinomas but not in healthy brain tissue.
  17. GC45403 CAY10735  
  18. GC47098 CL2-SN-38 (dichloroacetic acid salt) An antibody-drug conjugate containing SN-38
  19. GC43346 Cyclopamine-KAAD Cyclopamine-KAAD 是一种刺猬信号抑制剂,是一种平滑拮抗剂。
  20. GC43360 Cytostatin Cytostatin 是一种有效的选择性 PP2A 抑制剂,具有良好的抗肿瘤活性。 Cytostatin 也是细胞粘附到细胞外基质的抑制剂并诱导细胞凋亡。 Cytostatin 属于 fostriecin 家族的天然产物。
  21. GC43361 Cytostatin (sodium salt) Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cells metastatic activity in mice.
  22. GC45767 Dovitinib-d8 Dovitinib-D8 (CHIR-258-D8) 是氘标记的 Dovitinib。 Dovitinib (CHIR-258) 是一种多靶点酪氨酸激酶抑制剂,对 FLT3、c-Kit、FGFR1/FGFR3、VEGFR1/VEGFR2/ 的 IC50 为 1、2、8/9、10/13/8、27/210 nM VEGFR3 和 PDGFRα/PDGFRβ,分别。
  23. GC45448 Epitalon (acetate)  
  24. GC43719 Fusarisetin A Fusarisetin A 是一种五环真菌代谢物,是一种腺泡形态发生抑制剂。
  25. GC43727 Ganglioside GD1a mixture (sodium salt)

    Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver.

  26. GC43729 Ganglioside GD3 Mixture (sodium salt) Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases.
  27. GC43732 Ganglioside GM3 Mixture (sodium salt) Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation.
  28. GC47398 Genistein-d4 Genistein-d4 (NPI 031L-d4) 是氘标记的 Genistein。染料木黄酮是一种大豆异黄酮,是一种多种酪氨酸激酶(例如 EGFR)抑制剂,主要通过改变细胞凋亡、细胞周期和血管生成以及抑制转移来作为针对不同类型癌症的化学治疗剂。
  29. GC47400 GGTI 2133 (trifluoroacetate salt) A geranylgeranyl transferase I inhibitor
  30. GC43780 GM 1489 GM 1489 is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with Ki values of 0.002, 0.1, 0.5, 0.2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively.
  31. GC48387 Inostamycin A A bacterial metabolite with anticancer activity
  32. GC47459 Irinotecan-d10 (hydrochloride) Irinotecan-d10 ((+)-Irinotecan-d10) hydrochloride 是氘标记的 Irinotecan。 Irinotecan ((+)-Irinotecan) 是一种拓扑异构酶 I 抑制剂,通过与拓扑异构酶 I-DNA 复合物结合来阻止 DNA 链的再连接。
  33. GC18909 KRIBB3

    KRIBB3 is an Hsp27 and microtubule inhibitor that inhibits migration and invasion of MDA-MB-231 cells in vitro in an Hsp27-dependent manner.

  34. GC46015 KY 05009 KY 05009 是一种 ATP 竞争性 Traf2 和 Nck 相互作用激酶 (TNIK) 抑制剂,Ki 为 100 nM。 KY 05009 药理学抑制人肺腺癌细胞中 TGF-β1 诱导的上皮间质转化 (EMT)。 KY 05009 抑制 TNIK 的蛋白质表达和 Wnt 靶基因的转录活性,并诱导癌细胞凋亡。 KY 05009 具有抗癌活性。
  35. GC47582 Lupulone Lupulone 是一种来自啤酒花植物 H 的 β-酸。
  36. GP20741 MIF Human Macrophage Migration Inhibitory Factor Human Recombinant
  37. GP20744 MIF Human His C Macrophage Migration Inhibitory Factor Human Recombinant, His Tag C-Terminus
  38. GP20743 MIF Human His N Macrophage Migration Inhibitory Factor Human, Recombinant His Tag N-Terminus
  39. GP20742 MIF Human, Active Macrophage Migration Inhibitory Factor Human Recombinant (Active)
  40. GP20745 MIF Human, GST Macrophage Migration Inhibitor Factor Human Recombinant, GST tag
  41. GP20746 MIF Mouse Macrophage Migration Inhibitory Factor Mouse Recombinant
  42. GP20747 MIF Mouse, His Macrophage Migration Inhibitor Factor Mouse Recombinant, His Tag
  43. GP20748 MIF Rat Macrophage Migration Inhibitory Factor Rat Recombinant
  44. GP20749 MIF T.Vaginalis Macrophage Migration Inhibitor Factor Trichomonas Vaginalis Recombinant
  45. GC48479 Migrastatin A fungal metabolite with antimuscarinic and anticancer activities
  46. GC44222 ML-298 ML298 是一种有效的选择性磷脂酶 D2 (PLD2) 抑制剂,IC50 为 355 nM。 ML298 减少 U87-MG 胶质母细胞瘤细胞的侵袭性迁移。
  47. GC44223 ML-299 ML-299 是一种选择性变构调节剂和磷脂酶 D1 和 D2 的双重抑制剂(IC50 值分别为 6 和 12 nM)。 ML-299 减少 U87-MG 胶质母细胞瘤细胞的侵袭性迁移。
  48. GC18608 MMP-2/MMP-9 Inhibitor II MMP-2/MMP-9 inhibitor II is a dual inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 17 and 30 nM, respectively).
  49. GC18612 MMP-9/MMP-13 Inhibitor I MMP-9/MMP-13 inhibitor I is a cell-permeable inhibitor of matrix metalloproteinases (MMPs) that most potently inhibits MMP-9 and MMP-13 (IC50s = 0.9 nM for both).
  50. GC47720 N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine A microbial metabolite with anticancer activity
  51. GC44313 Naphthofluorescein Naphthofluorescein 抑制 HIF-1 和 Mint3 之间的相互作用。Naphthofluorescein 抑制 Mint3 依赖性 HIF-1 活性和癌细胞和巨噬细胞的糖酵解,在体外没有细胞毒性,在体内没有副作用。 Naphthofluorescein 也是一种荧光 pH 敏感探针,可用于功能性切伦科夫成像。

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