5-HT Receptor(5-羟色胺受体)
5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.
- Cat.No. 产品名称 Information
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GC26002
Trazodone
Trazodone (AF-1161) is a 5-HT 2A/2C receptor antagonist that is used as an antidepressant for treating major depressive disorder and anxiety disorders.
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GC25898
SB 200646
SB 200646 (SB 200646A) is a potent, selective and oral-active antagonist of 5-HT2B/2C over 5-HT2A receptor with 50 fold selectivity. The pKi for rat 5-HT2C receptor, rat 5-HT2B receptor and rat 5-HT2A receptor are 6.9, 7.5 and 5.2, respectively. SB 200646 has electrophysiological and anxiolytic properties in vivo.
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GC25756
Pirenperone
Pirenperone (R-47456, R-50656), a quinazoline derivative, is a selective antagonist of SR-2A (5-HT2 serotonin receptor) when employed in low doses. Pirenperone behaves like a typical neuroleptic when used in higher doses (greater than 0.1 mg/kg).
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GC25569
Lerisetron
Lerisetron (F 0930, F 0930RS) is a 5-HT3 receptor antagonist with IC50 of 0.81μM.
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GC25563
Lasmiditan succinate
Lasmiditan succinate (COL-144, LY573144) is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (Ki=2.21 nM) without vasoconstrictor activity.
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GC25434
Frovatriptan Succinate
Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.
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GC25259
Cisapride hydrate
Cisapride (Propulsid, Alimix, Propulsin, Enteropride, Kinestase) acts directly as a selective serotonin 5-HT4 receptor agonist with IC50 of 0.483 μM. And It also acts indirectly as a parasympathomimetic.
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GC25253
Cinitapride Hydrogen Tartrate
Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors
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GC68410
(S)-Mirtazapine-d3
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GC68364
Flibanserin-d4-1
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GC68328
3-Hydroxy agomelatine-d3
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GC68210
(+)-Norfenfluramine
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GC67989
(S)-Mirtazapine
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GC67937
(R)-Mirtazapine
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GC67923
Renzapride
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GC65983
5-HT3 antagonist 5
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GC65568
5-HT2B antagonist-1
WAY-388264-A is a bioactive compound.
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GC65565
Cyproheptadine
Cyproheptadine HCl(Periactin) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist.
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GC65296
Pimethixene maleate
Pimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimethixene maleate inhibits 5-HT2A, 5-HT2B, 5-HT2C, 5-HT1A, 5-HT1B, 5-HT6, 5-HT7, Adrenergic α-1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4.4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2 with pKi of 10.22, 10.44, 8.42, 7.63, < 5, 7.30, 7.28, 7.61, 6.37, 8.19, 7.54, 10.14, 8.61 and 9.38, respectively.
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GC65265
UNC9994 hydrochloride
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GC65014
DSP-1053
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GC64660
Usmarapride free base
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GC64606
Ro60-0175
A 5-HT2 receptor agonist
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GC64563
α-Methylserotonin
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GC64530
Sarizotan
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GC64423
Repinotan hydrochloride
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GC64265
Alosetron-13C,d3
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GC64182
5-Methoxytryptamine hydrochloride
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GC64080
Usmarapride
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GC63961
Cerlapirdine
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GC63842
Rodatristat
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GC63819
Asenapine maleate
Asenapine maleate (Org 5222) is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder.
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GC63682
Felcisetrag
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GC63632
(Rac)-Lorcaserin
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GC63599
Bufotenidine
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GC63432
Sertindole-d4
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GC63382
(Rac)-Lorcaserin hydrochloride
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GC63252
Velusetrag hydrochloride
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GC63251
Velusetrag
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GC63188
Serotonin
Serotonin HCl (5-HT) is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.
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GC63169
Relenopride hydrochloride
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GC63111
NLX-204 hydrochloride
NLX-204 is a potent, selective agonist of ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor with pKi of 10.19.
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GC63015
Iferanserin
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GC62967
F13714 fumarate
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GC62932
Didesmethyl cariprazine
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GC62799
4,4-Diphenylbutylamine hydrochloride
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GC62458
Rodatristat ethyl
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GC62417
Alniditan dihydrochloride
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GC61889
OPC-14523 hydrochloride
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GC61809
Olanzapine D3