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cAMP

cAMP (cyclic adenosine monophosphate) is a second messenger used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway.

  1. Cat.No. 产品名称 Information
  2. GC49440 ML-9 ML-9 是一种选择性强的 Akt 激酶抑制剂,抑制肌球蛋白轻链激酶 (MLCK) 和基质相互作用分子 1 (STIM1) 的活性。 ML-9 抑制 MLCK、PKA 和 PKC 活性,Ki 值分别为 4、32 和 54 μM。 ML-9 通过刺激自噬体形成并抑制其降解来诱导自噬。
  3. GC49285 Adenosine 5’-methylenediphosphate (hydrate) An inhibitor of ecto-5’-nucleotidase
  4. GC49186 O-Demethyl Apremilast An active metabolite of apremilast
  5. GC48920 β-Carboline-1-carboxylic Acid An alkaloid with diverse biological activities
  6. GC48469 Moexipril-d5 An internal standard for the quantification of moexipril
  7. GC48381 5'-pApA (sodium salt) A linearized form of cyclic di-AMP
  8. GC48329 PKA Inhibitor (5-24) (trifluoroacetate salt) A synthetic peptide inhibitor of PKA
  9. GC47931 PDE4B Inhibitor A PDE4B inhibitor
  10. GC47088 Cilostazol-d4 An internal standard for the quantification of cilostazol
  11. GC46554 2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate 2'-O-Monosuccinyladenosine-3',5'-环单磷酸盐是一种可以与乙酰胆碱酯酶共价偶联的 cAMP 类似物。
  12. GC60886 GSK356278 GSK356278是一种有效,选择性,具有口服活性和可透过血脑屏障的磷酸二酯酶4(PDE4)抑制剂,对人PDE4A,PDE4B和PDE4D的pIC50值分别为8.6、8.8和8.7。GSK356278具有抗炎活性,并具有抗焦虑和增强认知的作用。
  13. GC44920 Sp-8-bromo-Cyclic AMPS (sodium salt) Sp-8-bromo-cyclic AMPS (Sp-8-bromo-cAMPS) is a cell-permeable, cAMP analog that combines an exocyclic sulfur substitution in the axial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP.
  14. GC44852 Rp-8-bromo-Cyclic AMPS (sodium salt) Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP.
  15. GC44673 PQ-10 PQ-10 是一种有效的磷酸二酯酶 10A (PDE10A) 抑制剂,IC50 和 ED50 分别为 4.6 nM 和 13 mg/kg。
  16. GC44022 L-858,051 (hydrochloride) L-858,051 is a water-soluble analog of forskolin, a cell-permeant activator of adenylate cyclase.
  17. GC43798 Guanylyl Imidodiphosphate (lithium salt) Guanylyl imidodiphosphate (Gpp(NH)p) 锂是一种不可水解的 GTP 类似物,可增加腺苷酸环化酶活性。
  18. GC43341 Cyclic GMP

    Guanosine 3',5'-cyclic monophosphate (cyclic GMP or cGMP) is a second messenger that is biosynthesized from GTP by guanylate cyclases.

  19. GC43339 Cyclic di-AMP (sodium salt) Cyclic di-AMP (c-di-AMP) is a second messenger produced by bacteria but not by mammals.
  20. GC42622 8-bromo-Cyclic AMP 8-bromo-Cyclic AMP is a brominated derivative of cAMP that remains long-acting due to its resistance to degradation by cAMP phosphodiesterase.
  21. GC42616 7-oxo Staurosporine

    7-oxo Staurosporine is an antibiotic originally isolated from S.

  22. GC41635 Phosphodiesterase 4 Inhibitor Phosphodiesterase 4 (PDE4) inhibitor is an inhibitor of PDE4 with an IC50 value of 0.10 μM for the human recombinant enzyme.
  23. GC41423 5-trans Prostaglandin E2 5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1.
  24. GC18951 Obscurolide A1 Obscurolide A1 is a natural butyrolactone isolated from S.
  25. GC18751 Reticulol Reticulol is an isocoumarin derivative produced by certain species of Streptomyces that inhibits cAMP phosphodiesterase (IC50 = 41 uM).
  26. GC18532 Skyrin Skyrin is a fungal metabolite characterized by a bisanthraquinone structure.
  27. GC10005 SEP-0372814
  28. GC12834 6-Bnz-cAMP sodium salt cAMP analog,PKA activator
  29. GC10941 cAMPS-Rp, triethylammonium salt cAMPS-Rp 三乙基铵盐是一种 cAMP 类似物,是一种有效的、竞争性 cAMP 诱导的 cAMP 依赖性 PKA I 和 II 激活(Kis 分别为 12.5 μ;M 和 4.5 μ;M)拮抗剂。
  30. GC12706 cAMPS-Sp, triethylammonium salt cAMPS-Sp,三乙基铵盐,一种 cAMP 类似物,是一种有效的、竞争性 cAMP 诱导的 cAMP 依赖性 PKA I 和 II 的激活(Kis 分别为 12.5 μ;M 和 4.5 μ;M)拮抗剂。
  31. GC12824 Dibutyryl-cAMP, sodium salt Dibutyryl-cAMP, sodium salt salt (Dibutyryl-cAMP sodium salt) 是一种稳定的环 AMP (cAMP) 类似物和选择性 PKA 激活剂。
  32. GC16929 8-Bromo-cAMP, sodium salt 8-Bromo-cAMP, sodium salt (8-Br-Camp sodium salt),一种环状 AMP 类似物,是环状 AMP 依赖性蛋白激酶 (PKA) 的激活剂。

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