Home>>Signaling Pathways>> MAPK Signaling>> cAMP>>Cilostazol-d4

Cilostazol-d4 Sale

(Synonyms: 西洛他唑-D4,OPC-13013-d4) 目录号 : GC47088

An internal standard for the quantification of cilostazol

Cilostazol-d4 Chemical Structure

Cas No.:1215541-47-1

规格 价格 库存 购买数量
1 mg

电话:400-920-5774 Email: sales@glpbio.cn

Customer Reviews

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.


Quality Control & SDS

View current batch:


Cilostazol-d4 is intended for use as an internal standard for the quantification of cilostazol by GC- or LC-MS. Cilostazol is a phosphodiesterase 3A (PDE3A) inhibitor (IC50 = 0.2 µM for the platelet enzyme).1 It is selective for PDE3A over PDE1, -2, -4, and 5 (IC50s = >5 µM for all). Cilostazol inhibits collagen- or ADP-induced aggregation of isolated rabbit platelets (IC50s = 29 and 31 µM, respectively).2 In vivo, cilostazol (30 mg/kg) reduces thrombus formation by 84% in a mouse model of pulmonary thromboembolism. It reduces cardiac fibrosis and prevents the development of diastolic dysfunction and cardiac hypertrophy induced by a high-fat diet and angiotensin II in mice.3 Formulations containing cilostazol have been used in the treatment of the symptoms of intermittent claudication in peripheral vascular disease.

1.SchrÖr, K.The pharmacology of cilostazolDiabetes Obes. Metab.4 (Suppl 2)S14-S19(2002) 2.Koga, Y., Kihara, Y., Okada, M., et al.2(1H)-Quinolinone derivatives as novel anti-arteriostenotic agents showing anti-thrombotic and anti-hyperplastic activitiesBioorg. Med. Chem. Lett.8(12)1471-1476(1998) 3.Reddy, S.S., Agarwal, H., and Barthwal, M.K.Cilostazol ameliorates heart failure with preserved ejection fraction and diastolic dysfunction in obese and non-obese hypertensive miceJ. Mol. Cell. Cardiol.12346-57(2018)

Chemical Properties

Cas No. 1215541-47-1 SDF
别名 西洛他唑-D4,OPC-13013-d4
Canonical SMILES O=C(N1)CCC2=C1C=CC(OCCCCC3=NN=NN3C4C([2H])([2H])CCCC4([2H])[2H])=C2
分子式 C20H23D4N5O2 分子量 373.5
溶解度 DMSO: Slightly soluble,Methanol: Slightly soluble 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。


1 mg 5 mg 10 mg
1 mM 2.6774 mL 13.3869 mL 26.7738 mL
5 mM 0.5355 mL 2.6774 mL 5.3548 mL
10 mM 0.2677 mL 1.3387 mL 2.6774 mL
  • 摩尔浓度计算器

  • 稀释计算器

  • 分子量计算器

*在配置溶液时,请务必参考产品标签上、MSDS / COA(可在Glpbio的产品页面获得)批次特异的分子量使用本工具。


动物体内配方计算器 (澄清溶液)

给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
% DMSO % % Tween 80 % saline