NF-κB

NF-κB is a family of conserved and ubiquitous transcription factors that involved in various biological processes including immunity, inflammation, cell growth, differentiation and apoptosis. It is associated with cancer, chronic inflammation and arthritis etc.

Cat.No. 产品名称 Information
GC40266 (+)-Praeruptorin A A coumarin derivative
GC40264 (+)-Valencene A sesquiterpene
GC32705 (-)-DHMEQ (Dehydroxymethylepoxyquinomicin)
GC61564 (E/Z)-IT-603 (E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603. IT-603 is a NF-κB family member c-Rel inhibitor with an IC50 of 3 μM in electrophoretic mobility shift assay (EMSA).
GC13030 (R)-(-)-Ibuprofen A less potent enantiomer of ibuprofen
GC39321 (Rac)-Myrislignan
GC10821 11-keto-β-Boswellic Acid A 5-LO inhibitor
GC40763 14-deoxy-11,12-didehydro Andrographolide A noncytotoxic natural diterpenoid
GC68044 2,4,6-Trihydroxybenzaldehyde
GC39325 2,5-Dihydroxyacetophenone 2',5'-Dihydroxyacetophenone (DHAP, 2-Acetylhydroquinone, Quinacetophenone) is a mixture of dihydroxyacetophenone isomers is used in food flavouring. 2',5'-Dihydroxyacetophenone significantly inhibits NO production via the suppression of iNOS expression. 2',5'-Dihydroxyacetophenone significantly decreases levels of the pro-inflammatory cytokines TNF-α and IL-6 by blocking the ERK1/2 and NF-κB signaling pathways.
GC60467 21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione
GC42406 4'-hydroxy Chalcone A chalcone metabolite with diverse biological activities
GC38663 4-Hydroxychalcone A chalcone metabolite with diverse biological activities
GC35143 4-O-Methyl honokiol A phenol with diverse biological activities
GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid
GC35185 7,4'-Dihydroxyflavone A flavonoid with diverse biological activities
GC35199 8-Deoxygartanin
GN10212 8-O-Acetyl shanzhiside methyl ester 8-O-Acetyl shanzhisidemethylester (8-O-Acetyl shanzhisidemethylester) 是一种环烯醚萜苷，从西藏的一种民间药用植物Lamiophlomis rotata Kudo 的叶子中分离得到。
GC15598 Ac2-26 An annexin A1-mimetic peptide
GC35224 Ac2-26 TFA
GN10536 Aconine An active metabolite of aconitine
GC31693 Adelmidrol Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities.
GC67968 ALPK1-IN-2
GC39254 Anatabine dicitrate
GN10718 Andrographolide An inhibitor of NF-κB signaling
GC35340 Andropanolide
GN10685 Anemarsaponin B Anemarsaponin B 是一种甾体皂苷。
GN10579 Aristolochic Acid A A PLA₂ inhibitor
GC35394 Armepavine
GC35401 Asatone
GC35412 Asperulosidic Acid
GN10415 Astilbin A flavonoid with diverse biological activities
GC42880 Avenanthramide-C methyl ester Inhibitor of NF-κB activation
GC39280 B022
GN10018 Baicalin A flavonoid with diverse biological activities
GC10345 Bay 11-7085 An irreversible inhibitor of IκBα phosphorylation
GC13035 Bay 11-7821
A selective and irreversible NF-κB inhibitor
GC35494 Benzoyloxypaeoniflorin
GN10443 Berbamine A bisbenzylisoquinoline alkaloid with diverse biological activities
GN10358 Berbamine hydrochloride A bisbenzylisoquinoline alkaloid with diverse biological activities
GC10480 Betulinic acid A plant triterpenoid similar to bile acids
GC65010 Bortezomib-d8
GC40352 Cafestol A natural diterpene which increases serum cholesterol
GC10692 Caffeic Acid Phenethyl Ester A potent inhibitor of NF-κB activation
GC18069 Cardamonin A chalconoid with anti-inflammatory and anti-tumor activity
GC43165 CAY10512 A potent inhibitor of NF-κB
GC41601 CAY10591 A SIRT1 activator
GC43190 CAY10682 A dual inhibitor of p53-Mdm2 interaction and NF-κB signaling
GC15394 CBL0137 (hydrochloride) An activator of p53 and inhibitor of NF-κB
GC35629 CDDO-dhTFEA