Home >> Signaling Pathways >> Immunology/Inflammation >> NF-κB


NF-κB is a family of conserved and ubiquitous transcription factors that involved in various biological processes including immunity, inflammation, cell growth, differentiation and apoptosis. It is associated with cancer, chronic inflammation and arthritis etc.

  1. Cat.No. 产品名称 Information
  2. GC40266 (+)-Praeruptorin A A coumarin derivative
  3. GC40264 (+)-Valencene A sesquiterpene
  4. GC32705 (-)-DHMEQ (Dehydroxymethylepoxyquinomicin)
  5. GC61564 (E/Z)-IT-603 (E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603. IT-603 is a NF-κB family member c-Rel inhibitor with an IC50 of 3 μM in electrophoretic mobility shift assay (EMSA).
  6. GC13030 (R)-(-)-Ibuprofen A less potent enantiomer of ibuprofen
  7. GC39321 (Rac)-Myrislignan
  8. GC10821 11-keto-β-Boswellic Acid A 5-LO inhibitor
  9. GC40763 14-deoxy-11,12-didehydro Andrographolide A noncytotoxic natural diterpenoid
  10. GC68044 2,4,6-Trihydroxybenzaldehyde
  11. GC39325 2,5-Dihydroxyacetophenone 2',5'-Dihydroxyacetophenone (DHAP, 2-Acetylhydroquinone, Quinacetophenone) is a mixture of dihydroxyacetophenone isomers is used in food flavouring. 2',5'-Dihydroxyacetophenone significantly inhibits NO production via the suppression of iNOS expression. 2',5'-Dihydroxyacetophenone significantly decreases levels of the pro-inflammatory cytokines TNF-α and IL-6 by blocking the ERK1/2 and NF-κB signaling pathways.
  12. GC60467 21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione
  13. GC42406 4'-hydroxy Chalcone A chalcone metabolite with diverse biological activities
  14. GC38663 4-Hydroxychalcone A chalcone metabolite with diverse biological activities
  15. GC35143 4-O-Methyl honokiol A phenol with diverse biological activities
  16. GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid
  17. GC35185 7,4'-Dihydroxyflavone A flavonoid with diverse biological activities
  18. GC35199 8-Deoxygartanin
  19. GN10212 8-O-Acetyl shanzhiside methyl ester 8-O-Acetyl shanzhisidemethylester (8-O-Acetyl shanzhisidemethylester) 是一种环烯醚萜苷,从西藏的一种民间药用植物Lamiophlomis rotata Kudo 的叶子中分离得到。
  20. GC15598 Ac2-26 An annexin A1-mimetic peptide
  21. GC35224 Ac2-26 TFA
  22. GN10536 Aconine An active metabolite of aconitine
  23. GC31693 Adelmidrol Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities.
  24. GC67968 ALPK1-IN-2
  25. GC39254 Anatabine dicitrate
  26. GN10718 Andrographolide An inhibitor of NF-κB signaling
  27. GC35340 Andropanolide
  28. GN10685 Anemarsaponin B Anemarsaponin B 是一种甾体皂苷。
  29. GN10579 Aristolochic Acid A A PLA2 inhibitor
  30. GC35394 Armepavine
  31. GC35401 Asatone
  32. GC35412 Asperulosidic Acid
  33. GN10415 Astilbin A flavonoid with diverse biological activities
  34. GC42880 Avenanthramide-C methyl ester Inhibitor of NF-κB activation
  35. GC39280 B022
  36. GN10018 Baicalin A flavonoid with diverse biological activities
  37. GC10345 Bay 11-7085 An irreversible inhibitor of IκBα phosphorylation
  38. GC13035 Bay 11-7821

    A selective and irreversible NF-κB inhibitor

  39. GC35494 Benzoyloxypaeoniflorin
  40. GN10443 Berbamine A bisbenzylisoquinoline alkaloid with diverse biological activities
  41. GN10358 Berbamine hydrochloride A bisbenzylisoquinoline alkaloid with diverse biological activities
  42. GC10480 Betulinic acid A plant triterpenoid similar to bile acids
  43. GC65010 Bortezomib-d8
  44. GC40352 Cafestol A natural diterpene which increases serum cholesterol
  45. GC10692 Caffeic Acid Phenethyl Ester A potent inhibitor of NF-κB activation
  46. GC18069 Cardamonin A chalconoid with anti-inflammatory and anti-tumor activity
  47. GC43165 CAY10512 A potent inhibitor of NF-κB
  48. GC41601 CAY10591 A SIRT1 activator
  49. GC43190 CAY10682 A dual inhibitor of p53-Mdm2 interaction and NF-κB signaling
  50. GC15394 CBL0137 (hydrochloride) An activator of p53 and inhibitor of NF-κB
  51. GC35629 CDDO-dhTFEA

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