NF-κB
NF-κB is a family of conserved and ubiquitous transcription factors that involved in various biological processes including immunity, inflammation, cell growth, differentiation and apoptosis. It is associated with cancer, chronic inflammation and arthritis etc.
- Cat.No. 产品名称 Information
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GC40266
(+)-Praeruptorin A
A coumarin derivative
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GC40264
(+)-Valencene
A sesquiterpene
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GC32705
(-)-DHMEQ (Dehydroxymethylepoxyquinomicin)
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GC61564
(E/Z)-IT-603
(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603. IT-603 is a NF-κB family member c-Rel inhibitor with an IC50 of 3 μM in electrophoretic mobility shift assay (EMSA).
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GC13030
(R)-(-)-Ibuprofen
A less potent enantiomer of ibuprofen
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GC39321
(Rac)-Myrislignan
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GC10821
11-keto-β-Boswellic Acid
A 5-LO inhibitor
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GC40763
14-deoxy-11,12-didehydro Andrographolide
A noncytotoxic natural diterpenoid
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GC68044
2,4,6-Trihydroxybenzaldehyde
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GC39325
2,5-Dihydroxyacetophenone
2',5'-Dihydroxyacetophenone (DHAP, 2-Acetylhydroquinone, Quinacetophenone) is a mixture of dihydroxyacetophenone isomers is used in food flavouring. 2',5'-Dihydroxyacetophenone significantly inhibits NO production via the suppression of iNOS expression. 2',5'-Dihydroxyacetophenone significantly decreases levels of the pro-inflammatory cytokines TNF-α and IL-6 by blocking the ERK1/2 and NF-κB signaling pathways.
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GC60467
21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione
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GC42406
4'-hydroxy Chalcone
A chalcone metabolite with diverse biological activities
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GC38663
4-Hydroxychalcone
A chalcone metabolite with diverse biological activities
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GC35143
4-O-Methyl honokiol
A phenol with diverse biological activities
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GC52413
5-Aminosalicylic Acid-d7
An internal standard for the quantification of 5-aminosalicylic acid
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GC35185
7,4'-Dihydroxyflavone
A flavonoid with diverse biological activities
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GC35199
8-Deoxygartanin
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GN10212
8-O-Acetyl shanzhiside methyl ester
8-O-Acetyl shanzhisidemethylester (8-O-Acetyl shanzhisidemethylester) 是一种环烯醚萜苷,从西藏的一种民间药用植物Lamiophlomis rotata Kudo 的叶子中分离得到。
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GC15598
Ac2-26
An annexin A1-mimetic peptide
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GC35224
Ac2-26 TFA
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GN10536
Aconine
An active metabolite of aconitine
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GC31693
Adelmidrol
Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities.
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GC67968
ALPK1-IN-2
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GC39254
Anatabine dicitrate
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GN10718
Andrographolide
An inhibitor of NF-κB signaling
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GC35340
Andropanolide
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GN10685
Anemarsaponin B
Anemarsaponin B 是一种甾体皂苷。
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GN10579
Aristolochic Acid A
A PLA2 inhibitor
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GC35394
Armepavine
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GC35401
Asatone
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GC35412
Asperulosidic Acid
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GN10415
Astilbin
A flavonoid with diverse biological activities
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GC42880
Avenanthramide-C methyl ester
Inhibitor of NF-κB activation
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GC39280
B022
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GN10018
Baicalin
A flavonoid with diverse biological activities
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GC10345
Bay 11-7085
An irreversible inhibitor of IκBα phosphorylation
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GC13035
Bay 11-7821
A selective and irreversible NF-κB inhibitor
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GC35494
Benzoyloxypaeoniflorin
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GN10443
Berbamine
A bisbenzylisoquinoline alkaloid with diverse biological activities
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GN10358
Berbamine hydrochloride
A bisbenzylisoquinoline alkaloid with diverse biological activities
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GC10480
Betulinic acid
A plant triterpenoid similar to bile acids
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GC65010
Bortezomib-d8
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GC40352
Cafestol
A natural diterpene which increases serum cholesterol
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GC10692
Caffeic Acid Phenethyl Ester
A potent inhibitor of NF-κB activation
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GC18069
Cardamonin
A chalconoid with anti-inflammatory and anti-tumor activity
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GC43165
CAY10512
A potent inhibitor of NF-κB
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GC41601
CAY10591
A SIRT1 activator
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GC43190
CAY10682
A dual inhibitor of p53-Mdm2 interaction and NF-κB signaling
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GC15394
CBL0137 (hydrochloride)
An activator of p53 and inhibitor of NF-κB
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GC35629
CDDO-dhTFEA