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Home >> Signaling Pathways >> Immunology/Inflammation >> NF-κB

NF-κB

NF-κB is a family of conserved and ubiquitous transcription factors that involved in various biological processes including immunity, inflammation, cell growth, differentiation and apoptosis. It is associated with cancer, chronic inflammation and arthritis etc.

Products for  NF-κB

  1. Cat.No. 产品名称 Information
  2. GC49024 Palmitic Acid MaxSpec® Standard A long-chain saturated fatty acid
  3. GC49023 Palmitic Acid-d9 MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications
  4. GN10357 Parthenolide A natural inhibitor of NOD2 and NF-κB signaling
  5. GC60283 Pentagamavunon-1 Pentagamavunon-1 (PGV-1) 是Curcumin 的类似物，具有口服活性，通过多个机制诱导凋亡信号，如抑制COX-2 和 VEGF。Pentagamavunon-1 (PGV-1) 可抑制 NF-κB 的激活。
  6. GC38170 Phellodendrine An alkaloid with diverse biological activities
  7. GN10778 Picroside II A flavonoid with diverse biological activities
  8. GN10312 Polygalasaponin F A triterpenoid saponin with diverse biological activities
  9. GC16657 PPM-18 Inhibits activation of NF-κB
  10. GC16096 PR 39 (porcine) PR 39（猪）是一种富含脯氨酸和精氨酸的天然抗菌肽，是一种非竞争性、可逆的变构蛋白酶体抑制剂。
  11. GC37036 PTD-p65-P1 Peptide PTD-p65-P1 Peptide 是一种核转录因子 NF-kappaB 抑制剂，由一个 antennapedia 衍生的膜转运肽序列 (PTD) 连接 p65-P1 构成, 选择性地抑制由各种刺激诱导的 NF-kappaB 活性。
  12. GC38520 PTD-p65-P1 Peptide TFA PTD-p65-P1 Peptide TFA 是一种核转录因子 NF-kappaB 抑制剂，由一个 antennapedia 衍生的膜转运肽序列 (PTD) 连接 p65-P1 构成, 选择性地抑制由各种刺激诱导的 NF-kappaB 活性。
  13. GC49860 Pyropheophorbide a methyl ester A photosensitizer
  14. GC13575 Pyrrolidinedithiocarbamate ammonium A potent and reversible NF-κB inhibitor with antioxidant properties
  15. GC11751 QNZ (EVP4593) An inhibitor of NF-κB activation
  16. GC39428 Quinoclamine Quinoclamine 是一种萘醌衍生物，是一种 NF-κB 抑制剂。Quinoclamine 具有抗肿瘤活性。
  17. GC39081 Reticuline Reticuline 分离自 Litsea cubeba，通过 JAK2/STAT3 和 NF-κB 信号通路显示抗炎作用。Reticuline 还可抑制 TNF-α 和 IL-6 的 mRNA 表达，并降低 JAK2 和 STAT3 的磷酸化水平。
  18. GN10784 Rhoifolin A flavonoid glycoside with diverse biological activities
  19. GN10185 Rhynchophylline Rhyncholphylline 是一种从钩藤属植物中分离出来的生物碱，在大鼠原代小胶质细胞中显示出对脂多糖 (LPS) 诱导的 NO 产生的有效抑制作用。
  20. GC16874 Ro 106-9920 An inhibitor of IκBα ubiquitination
  21. GC33426 Rocaglamide (Rocaglamide A)

    Rocaglamide (Rocaglamide A) is isolated from the genus Aglaia (family Meliaceae). 
  22. GC60331 Rubiadin-1-methyl ether An anthraquinone with diverse biological activities
  23. GN10164 Saikosaponin D A triterpene saponin with diverse biological activities
  24. GN10759 Sanggenone C A flavonoid with diverse biological activities
  25. GN10260 Sarsasapogenin A steroid sapogenin with diverse biological activities
  26. GC10088 SC75741 An inhibitor of NF-κB
  27. GN10368 Schisantherin A A hepatoprotective antioxidant
  28. GC45561 Sciadopitysin A biflavonoid with diverse biological activities
  29. GC68141 SEMBL SEMBL 是一种有效的 NF-κB 抑制剂。SEMBL 能够抑制 NF-κB-DNA 结合，还抑制 NF-κB 依赖性炎性细胞因子分泌。SEMBL 通过降低 MMP 表达来抑制癌细胞的迁移和侵袭。可用于抗癌研究。
  30. GN10216 Shikonin A natural product with anti-inflammatory and anti-tumor activity
  31. GC49002 Sinigrin (hydrate) A glucosinolate with diverse biological activities
  32. GN10213 Sinomenine Hydrochloride A natural anti-inflammatory alkaloid
  33. GC49049 SMU127 An agonist of TLR1/2
  34. GC31642 SN50 SN50, the NF-κB cell permeable inhibitory peptide.
  35. GC10933 Sodium 4-Aminosalicylate 4-氨基水杨酸钠（4-氨基水杨酸钠盐二水合物）是目前用于耐多药结核病的抗分枝杆菌药物之一。
  36. GC12013 Sodium salicylate 水杨酸钠（水杨酸钠盐）抑制环加氧酶 2（COX-2）活性，与转录因子（NF-κB）激活无关。
  37. GC50139 SP 100030 SP 100030 是一种有效的 NF-κB 和 activator protein-1 (AP-1) 双抑制剂（IC50s 分别为 50 和 50 nM）。
  38. GC37686 Stachydrine A pyrrolidine betaine with anticancer and cardioprotective effects
  39. GC13840 Stachydrine (hydrochloride) A pyrrolidine betaine with anticancer and cardioprotective effects
  40. GC49844 Stercobilin (hydrochloride) A fecal pigment and metabolite of bilirubin
  41. GC11819 Strontium Ranelate An antiosteoporotic agent
  42. GC38984 Suberosin A prenylated coumarin with diverse biological activities
  43. GC16868 Sulfasalazine A prodrug form of 5-aminosalicylic acid
  44. GC32737 TAK-243 (MLN7243) A UAE inhibitor
  45. GC60352 Taraxerol Taraxerol 具有抗炎和抗癌作用。
  46. GC34171 Tectochrysin (Techtochrysin) A flavonoid with diverse biological activities
  47. GC41573 Theaflavin 3,3'-digallate

    A polyphenol with diverse biological activities
  48. GC31647 Tomatidine A steroidal alkaloid with diverse biological activities
  49. GC45064 Tomatidine (hydrochloride) A steroidal alkaloid with diverse biological activities
  50. GC38868 TRAF-STOP inhibitor 6877002 TRAF-STOP inhibitor 6877002，一种抑制 CD40-TRAF6 相互作用的选择性抑制剂，从专利 WO2014033122A1 中获得，抑制 RAW 细胞中 NF-κB 活化，化合物VII。TRAF-STOP 6877002 可阻止小鼠中已发生的动脉粥样硬化恶化，减少白细胞募集并减少巨噬细胞活化；减少动脉粥样硬化斑块中的巨噬细胞增殖。
  51. GC48202 Treprostinil (diethanolamine salt) An agonist of IP2, DP2, and EP2 receptors

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