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Home >> Signaling Pathways >> Others >> MDR multidrug resistance

MDR multidrug resistance(多药耐药)

MDR (multidrug resistance) is a property that first identified in tumor cell, hat the resistance of tumor cell is to a variety of chemotherapy agent due to active efflux via transporter proteins.

Products for  MDR multidrug resistance

  1. Cat.No. 产品名称 Information
  2. GC45246 (-)-Chaetominine

    (-)-Chaetominine

     A cytotoxic alkaloid
  3. GC41865 10'-Desmethoxystreptonigrin

    10-去甲氧基链黑霉素

     An antibiotic
  4. GC45324 2,5-dimethyl Celecoxib

    2,5-二甲基塞来考昔

     An anticancer celecoxib derivative
  5. GC91154 33-BCRP Inhibitor

    33-Breast Cancer Resistance Protein Inhibitor

    一种BCRP抑制剂
  6. GC91135 4-(3,4-Difluorobenzo)curcumin

    CDF

    一种半合成的香豆素，具有抗寄生虫和抗癌活性。
  7. GC42616 7-oxo Staurosporine

    BMY 41950, RK-1409

     An antibiotic with diverse biological activities
  8. GC49275 8-Oxycoptisine

    8-氧黄连碱

     An isoquinoline alkaloid with anticancer and gastroprotective activities
  9. GC46809 Afatinib-d6

    BIBW 2992 D6

     An internal standard for the quantification of afatinib
  10. GC42806 Andrastin A

    NSC 697452

     A meroterpenoid farnesyltransferase inhibitor
  11. GC43004 C10 Ceramide (d18:1/10:0)

    N-癸酰-D-鞘胺醇,N-decanoyl-D-erythro-Sphingosine

     A bioactive sphingolipid
  12. GC43060 C2 Adamantanyl Globotriaosylceramide (d18:1/2:0) C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain.
  13. GC45395 Cabazitaxel-d9

    XRP6258-d9; RPR-116258A-d9; taxoid XRP6258-d9

     An internal standard for the quantification of cabazitaxel
  14. GC45679 Carubicin

    洋红霉素,Carminomycin; Carminomicin I

     An anthracycline with anticancer activity
  15. GC40795 CAY10503 A proapoptotic, antiproliferative compound
  16. GC18901 CAY10647 An inhibitor of tubulin polymerization and cancer cell growth
  17. GC45792 Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)

    Iron Salophene Complex, N,N'-o-Phenylenebis(salicylideneaminato)iron(III) Chloride

     An inducer of ferroptosis
  18. GC90543 EGFR Peptide (human, mouse) (myristoylated) (trifluoroacetate salt)

    Epidermal Growth Factor Receptor Peptide, Myr-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH, N-myristoyl-RKRTLRRL

    一种PKC抑制剂
  19. GC46004 Evoxanthine

    NSC 407812

     An alkaloid
  20. GC91152 Flavokawain 1i

    Flavokavain 1i

    一种具有抗癌和抗病毒活性的黄樟素衍生物。
  21. GC90660 Fz25

    一种三唑修饰的甾醇和抗癌药物。
  22. GC49106 Gentisein

    1,3,7-三羟基-9H-氧杂蒽-9-酮,NSC 329491; 1,3,7-Trihydroxyxanthone

     A xanthone with diverse biological activities
  23. GC47409 Glycocholic Acid-d4

    甘氨胆酸-D4

     An internal standard for the quantification of glycocholic acid
  24. GC91057 HP661

    一种线粒体复合物I抑制剂。
  25. GC91403 HR68

    PP21

     HR68是一种抗癌药物，是过氧化物酶体增殖激活受体（PPAR）激动剂芬布拉酸的衍生物。它可以降低LN-229恶性胶质母细胞瘤细胞的存活率（IC50 = 1.17uM）。
  26. GC49670 Indium (III) thiosemicarbazone 5b An anticancer agent
  27. GC44129 MC 70 A P-glycoprotein inhibitor
  28. GC48479 Migrastatin

    (+)-Migrastatin

     A fungal metabolite with antimuscarinic and anticancer activities
  29. GC44195 Milbemycin A4 oxime

    美倍霉素肟A4

     A derivative of milbemycin A4
  30. GC41564 MPT0B014 An inhibitor of tubulin polymerization
  31. GC45784 ONT-093

    OC 144-093; OC 144093

     A P-glycoprotein inhibitor
  32. GC49251 Oxaliplatin-d10

    Lipoxal-d10

     An internal standard for the quantification of oxaliplatin
  33. GC44613 PF-6274484 An EGFR inhibitor
  34. GC44615 PGP-4008 A selective P-glycoprotein inhibitor
  35. GC41629 Piperafizine A A P-glycoprotein inhibitor
  36. GC52455 Pixantrone-d8 (maleate) An internal standard for the quantification of pixantrone
  37. GC52104 Ponatinib (hydrochloride)

    泊那替尼盐酸盐,AP24534 hydrochloride

     An inhibitor of native and mutant Bcr-Abl
  38. GC17403 Pyronaridine Tetraphosphate

    4-[(7-氯-2-甲氧基-1,5-二氢吡啶并[3,2-b]喹啉-10-基)亚氨]-2,6-二(吡咯烷-1-基甲基)环己-2,5-二烯-1-酮磷酸盐(1:4),Malaridine

    An antimalarial agent
  39. GC44821 Reversin 121 A hydrophobic peptide chemosensitizer
  40. GC91096 S-72

    一种微管聚合抑制剂。
  41. GC45688 STX140

    2-Methoxyestradiol-bis-sulphamate

     An estrogen sulfamate
  42. GC48119 Suprafenacine

    SML1493

     An inhibitor of tubulin polymerization with anticancer activity
  43. GC48219 Ulipristal Acetate-d6

    CDB-2914-d6

     An internal standard for the quantification of ulipristal acetate
  44. GC49308 Ungeremine

    石蒜碱内铵盐

     A betaine-type alkaloid with diverse biological activities
  45. GC91435 YCH1899 YCH1899是一种聚(ADP-核糖)聚合酶1(PARP1)和PARP2的抑制剂(IC50s = 1)，它选择性地作用于PARP1和PARP2，而不影响PARP3、-4、-5A、-5B、-6、-7、-10和-12 (IC50s = 1 -14.1 nM)。

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