MDR multidrug resistance(多药耐药)
MDR (multidrug resistance) is a property that first identified in tumor cell, hat the resistance of tumor cell is to a variety of chemotherapy agent due to active efflux via transporter proteins.
Products for MDR multidrug resistance
- Cat.No. 产品名称 Information
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GC45246
(-)-Chaetominine
(-)-Chaetominine
A cytotoxic alkaloid -
GC41865
10'-Desmethoxystreptonigrin
10-去甲氧基链黑霉素
An antibiotic -
GC45324
2,5-dimethyl Celecoxib
2,5-二甲基塞来考昔
An anticancer celecoxib derivative -
GC91154
33-BCRP Inhibitor
33-Breast Cancer Resistance Protein Inhibitor
一种BCRP抑制剂
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GC91135
4-(3,4-Difluorobenzo)curcumin
CDF
一种半合成的香豆素,具有抗寄生虫和抗癌活性。
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GC42616
7-oxo Staurosporine
BMY 41950, RK-1409
An antibiotic with diverse biological activities -
GC49275
8-Oxycoptisine
8-氧黄连碱
An isoquinoline alkaloid with anticancer and gastroprotective activities -
GC46809
Afatinib-d6
BIBW 2992 D6
An internal standard for the quantification of afatinib -
GC42806
Andrastin A
NSC 697452
A meroterpenoid farnesyltransferase inhibitor -
GC43004
C10 Ceramide (d18:1/10:0)
N-癸酰-D-鞘胺醇,N-decanoyl-D-erythro-Sphingosine
A bioactive sphingolipid - GC43060 C2 Adamantanyl Globotriaosylceramide (d18:1/2:0) C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain.
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GC45395
Cabazitaxel-d9
XRP6258-d9; RPR-116258A-d9; taxoid XRP6258-d9
An internal standard for the quantification of cabazitaxel -
GC45679
Carubicin
洋红霉素,Carminomycin; Carminomicin I
An anthracycline with anticancer activity - GC40795 CAY10503 A proapoptotic, antiproliferative compound
- GC18901 CAY10647 An inhibitor of tubulin polymerization and cancer cell growth
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GC45792
Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
Iron Salophene Complex, N,N'-o-Phenylenebis(salicylideneaminato)iron(III) Chloride
An inducer of ferroptosis -
GC90543
EGFR Peptide (human, mouse) (myristoylated) (trifluoroacetate salt)
Epidermal Growth Factor Receptor Peptide, Myr-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH, N-myristoyl-RKRTLRRL
一种PKC抑制剂
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GC46004
Evoxanthine
NSC 407812
An alkaloid -
GC91152
Flavokawain 1i
Flavokavain 1i
一种具有抗癌和抗病毒活性的黄樟素衍生物。
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GC90660
Fz25
一种三唑修饰的甾醇和抗癌药物。
-
GC49106
Gentisein
1,3,7-三羟基-9H-氧杂蒽-9-酮,NSC 329491; 1,3,7-Trihydroxyxanthone
A xanthone with diverse biological activities -
GC47409
Glycocholic Acid-d4
甘氨胆酸-D4
An internal standard for the quantification of glycocholic acid -
GC91057
HP661
一种线粒体复合物I抑制剂。
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GC91403
HR68
PP21
HR68是一种抗癌药物,是过氧化物酶体增殖激活受体(PPAR)激动剂芬布拉酸的衍生物。它可以降低LN-229恶性胶质母细胞瘤细胞的存活率(IC50 = 1.17uM)。 - GC49670 Indium (III) thiosemicarbazone 5b An anticancer agent
- GC44129 MC 70 A P-glycoprotein inhibitor
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GC48479
Migrastatin
(+)-Migrastatin
A fungal metabolite with antimuscarinic and anticancer activities -
GC44195
Milbemycin A4 oxime
美倍霉素肟A4
A derivative of milbemycin A4 - GC41564 MPT0B014 An inhibitor of tubulin polymerization
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GC45784
ONT-093
OC 144-093; OC 144093
A P-glycoprotein inhibitor -
GC49251
Oxaliplatin-d10
Lipoxal-d10
An internal standard for the quantification of oxaliplatin - GC44613 PF-6274484 An EGFR inhibitor
- GC44615 PGP-4008 A selective P-glycoprotein inhibitor
- GC41629 Piperafizine A A P-glycoprotein inhibitor
- GC52455 Pixantrone-d8 (maleate) An internal standard for the quantification of pixantrone
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GC52104
Ponatinib (hydrochloride)
泊那替尼盐酸盐,AP24534 hydrochloride
An inhibitor of native and mutant Bcr-Abl -
GC17403
Pyronaridine Tetraphosphate
4-[(7-氯-2-甲氧基-1,5-二氢吡啶并[3,2-b]喹啉-10-基)亚氨]-2,6-二(吡咯烷-1-基甲基)环己-2,5-二烯-1-酮磷酸盐(1:4),Malaridine
An antimalarial agent
- GC44821 Reversin 121 A hydrophobic peptide chemosensitizer
-
GC91096
S-72
一种微管聚合抑制剂。
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GC45688
STX140
2-Methoxyestradiol-bis-sulphamate
An estrogen sulfamate -
GC48119
Suprafenacine
SML1493
An inhibitor of tubulin polymerization with anticancer activity -
GC48219
Ulipristal Acetate-d6
CDB-2914-d6
An internal standard for the quantification of ulipristal acetate -
GC49308
Ungeremine
石蒜碱内铵盐
A betaine-type alkaloid with diverse biological activities - GC91435 YCH1899 YCH1899是一种聚(ADP-核糖)聚合酶1(PARP1)和PARP2的抑制剂(IC50s = 1),它选择性地作用于PARP1和PARP2,而不影响PARP3、-4、-5A、-5B、-6、-7、-10和-12 (IC50s = 1 -14.1 nM)。