AChR(乙酰胆碱受体)
AChR, also known as acetylcholine receptor, is an integral membrane protein that responds to the binding of acetylcholine.
Products for AChR
- Cat.No. 产品名称 Information
- GC26093 α-Conotoxin GI α-Conotoxin GI, a 13-residue peptide originally isolated from the venom of the fish-hunting cone snail Conus geographus, acts as a competitive antagonist for the muscle-type nicotinic acetylcholine receptor (nAChR) with excellent selectivity for α/δ receptor subunit binding over α/γ.
- GC26032 Varenicline (CP 526555) dihydrochloride Varenicline (CP 526555, Chantix, Champix,CP 526555 dihydrochloride) dihydrochloride is a potent, partial agonist of α4β2 nicotinic acetylcholine receptor (nAChR) and α3β4 nAChR with EC50 of 2.3 μM and 55 μM, respectively. Varenicline dihydrochloride is a potent, full agonist of α7 nAChRs with EC50 of 18 μM. Varenicline is a prescription medication used for smoking cessation.
- GC25994 Thonzylamine Thonzylamine (Neohetramine) is an antihistamine and anticholinergic drug.
- GC25583 Lobelin sulphate Lobelin sulphate (Lobeline sulfate, Bantron) is an alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent. It has a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.
- GC25387 Ethyl (triphenylphosphoranylidene) acetate Ethyl (triphenylphosphoranylidene) acetate (Triphenylcarbethoxymethylenephosphorane, (Carbethoxymethylene)triphenylphosphorane) may act as an inhibitor of cholinesterase that inhibits AChE and BChE.
- GC17885 VU0364572 (trifluoroacetate salt) A selective muscarinic M1 receptor agonist
- GC13314 L-Acetylcarnitine (hydrochloride) A mitochondrial metabolite
- GC12507 ML352 An inhibitor of the presynaptic choline transporter
- GC13445 LY2119620 A positive allosteric modulator of M2 and M4 mAChRs
- GC17627 Nitenpyram An insecticide
- GC11128 (±)-Vesamicol hydrochloride (±)-Vesamicol hydrochloride ((±)-AH5183 hydrochloride) 是一种有效的囊泡乙酰胆碱转运抑制剂,Ki 为 2 nM。
- GC13361 Flavoxate hydrochloride An internal standard for the quantification of flavoxate
- GC10508 Solifenacin hydrochloride Solifenacin hydrochloride (YM905 hydrochloride) 是一种毒蕈碱受体拮抗剂,对 M1、M2 和 M3 受体的 pKis 分别为 7.6、6.9 和 8.0。
- GC14419 Bethanechol chloride A muscarinic acetylcholine receptor agonist
- GC14142 Acetylcholine Chloride A neurotransmitter
- GC11773 Pancuronium dibromide Pancuronium dibromide 是一种双季铵盐类固醇,是一种神经肌肉松弛剂。
- GC10972 Gallamine Triethiodide An allosteric modulator of muscarinic acetylcholine receptors
- GC17483 Trospium chloride An antagonist of muscarinic receptors
- GC13134 Tiotropium Bromide hydrate A muscarinic receptor antagonist
- GC17229 Paroxetine HCl A selective serotonin reuptake inhibitor
- GC17825 Methscopolamine A muscarinic acetylcholine receptor antagonist
- GC13779 Orphenadrine Citrate Orphenadrine citrate 是一种具有口服活性且非竞争性的 NMDA 受体拮抗剂(穿过血脑屏障),Ki 为 6.0 μM。
- GC15150 Tropicamide A selective muscarinic M4 antagonist
- GC12453 Succinylcholine Chloride Dihydrate An agonist of muscle-type nAChRs
- GC16056 Neostigmine Bromide 溴化新斯的明是一种胆碱酯酶抑制剂,用于治疗重症肌无力。
- GC10863 Otilonium Bromide An L- and T-type calcium channel inhibitor and mAChR antagonist
- GC11035 Hyoscyamine A muscarinic receptor antagonist
- GC17908 Homatropine Methylbromide An anticholinergic agent
- GC13897 Homatropine Bromide An anticholinergic agent
- GC15178 Hexamethonium Bromide A nondepolarizing neuromuscular blocking agent
- GC16255 Decamethonium Bromide A depolarizing neuromuscular blocking agent
- GC14703 Oxybutynin chloride An antagonist of muscarinic acetylcholine receptors
- GC12920 Pregnenolone A natural steroid hormone
- GC11219 (R)-(+)-Tolterodine (R)-(+)-Tolterodine(PNU-200583) 是一种有效的毒蕈碱受体拮抗剂,在体内对膀胱的选择性优于唾液腺。
- GC15029 Glycopyrrolate A muscarinic acetylcholine receptor antagonist
- GC16059 Tarafenacin D-tartrate Tarafenacin D-tartrate (SVT-40776 D-tartrate) 是一种高度选择性的 M3 毒蕈碱受体拮抗剂 (Ki= 0.19 nM),选择性是 M2 受体的约 200 倍。
- GC13618 Tarafenacin Tarafenacin(SVT-40776) 是一种高度选择性的 M3 毒蕈碱受体拮抗剂 (Ki= 0.19 nM),选择性比 M2 受体高约 200 倍。
- GC16819 VU0152100 A muscarinic M4 receptor positive allosteric modulator
- GC11643 PNU-120596 An α7 neuronal nAChR modulator
- GC12717 Ipratropium Bromide A muscarinic receptor antagonist
- GC16635 Diphemanil Methylsulfate An anticholinergic agent
- GC12994 Rivastigmine Tartrate A cholinesterase inhibitor
- GC14113 Oxybutynin An antagonist of muscarinic acetylcholine receptors
- GC16526 Atropine A non-selective muscarinic acetylcholine receptor antagonist
- GC11786 Acetylcysteine An antioxidant and glutathione precursor
- GC10948 Varenicline Tartrate An agonist of α7 and α4β2 nAChRs
- GC11210 Vecuronium Bromide A non-depolarizing muscle relaxant
- GC14624 Galanthamine HBr An alkaloid with AChE inhibitory and nAChR potentiating activities
- GC13449 Rocuronium Bromide A non-depolarizing muscle relaxant
- GC12554 Tiotropium Bromide A muscarinic receptor antagonist