GluR(谷氨酸受体)
GluR (glutamate receptor) is a group of synaptic receptors located primarily on the membranes of neuronal cells.
Products for GluR
- Cat.No. 产品名称 Information
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GC26056
WAY-303290
GluR6 antagonist-1
WAY-303290 (GluR6 antagonist-1) is a benzothiophene derivative acting as an ionotropic glutamate receptor 6 (GluR6) antagonist, which can be used for researching acute and chronic neurological disorders. -
GC18309
LSN2463359
N-异丙基-5-(吡啶-4-基乙炔基)吡啶酰胺
A brain penetrant positive allosteric modulator of the mGluR5 - GC16247 DCG IV DCG IV 是 II 组 mGluRs 的有效激动剂,对 mGlu2R 和 mGlu3R 的 EC50 分别为 0.35 和 0.09 μM。
- GC17950 MMPIP hydrochloride A reversible allosteric antagonist of mGluR7
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GC15342
(RS)-3,5-DHPG
(RS)-3,5-二羟基苯甘氨酸,DHPG
DHPG ((RS)-3,5-DHPG) 是一种氨基酸,是 I 组 mGluR(mGluR 1 和 mGluR 5)的选择性强效激动剂,对 II 组和 III 组 mGluR 没有影响 。 -
GC17932
L-AP4
L(+)-2-氨基-4-膦酰基丁酸,L-APB
A selective Group III metabotropic glutamate receptor agonist - GC17095 ML 337 ML 337 是一种选择性和脑渗透性的 mGlu3 负变构调节剂,IC50 为 593 nM。
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GC14869
ML 289
VU0463597
A negative allosteric modulator of mGlu3 - GC10045 MFZ 10-7 MFZ 10-7 是一种有效的 mGluR5 拮抗剂。
- GC12460 ADX 10059 hydrochloride Negative allosteric modulator at mGlu5
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GC11986
VU 0360223
CAY10651
A negative allosteric modulator of the mGlu5 receptor - GC10238 MNI 137 MNI 137 是一种有效的、选择性的负变构调节剂,适用于 II 组 mGluR。
- GC16643 VU 0285683 negative allosteric modulator of mGlu5 receptors
- GC11750 TC-N 22A TC-N 22A 是一种有效的、选择性的、具有口服活性和脑渗透性的 mGlu4 PAM,在表达人 mGlu4 的 BHK 细胞中的 EC50 为 9 nM。
- GC12485 Ro 67-7476 A positive allosteric modulator of mGluR1
- GC10323 VU 0360172 hydrochloride A positive allosteric modulator of mGluR5
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GC11563
NPS 2390
Type I metabotropic glutamate receptor antagonist
- GC18063 YM 230888 Selective mGlu1 antagonist
- GC12435 ACPT-I An mGluR4a and mGluR8 agonist
- GC16557 LY 379268 disodium salt group II mGlu receptor agonist
- GC14722 LY 2389575 hydrochloride negative allosteric modulator of mGlu3
- GC17289 VU 29 VU 29 是代谢型谷氨酸 5 (mGlu5) 受体的正变构调节剂(对于 rmGluR5,EC50\u003d9 nM 和 Ki\u003d244 nM)。
- GC14383 Ro 01-6128 A positive allosteric modulator of mGLUR1
- GC14172 Ro 67-4853 A positive allosteric modulator of mGlu1 receptors
- GC11501 TCN 238 A positive allosteric modulator of mGluR4
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GC12705
Cinnabarinic acid
朱砂精酸
An agonist of mGluR4 and active metabolite of 3-hydroxyanthranilic acid
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GC12510
BINA
3'-[[(2-环戊基-6,7-二甲基-1-氧代-2,3-二氢-1H-茚-5-基)氧基]甲基]联苯-4-羧酸,BINA
A positive allosteric modulator of mGluR2 - GC12899 CBiPES hydrochloride positive allosteric modulator of the mGlu2 receptor
- GC11997 (RS)-MCPG disodium salt group I/group II metabotropic glutamate receptor antagonist
- GC17963 CHPG Sodium salt CHPG 钠盐是一种选择性 mGluR5 激动剂,可通过 BV2 小胶质细胞中的 TSG-6/NF-κB 通路减弱 SO2 诱导的氧化应激和炎症。
- GC11970 YM 202074 metabotropic glutamate receptor type 1 (mGlu1) antagonist
- GC17604 NPEC-caged-(1S,3R)-ACPD group I and II mGlu receptor agonist
- GC11554 NPEC-caged-(S)-3,4-DCPG mGlu8a agonist
- GC17749 VU 1545 VU 1545 是一种代谢型谷氨酸受体 5 正变构调节剂 (mGluR5 PAM),Ki 为 156 nM,EC50 为 9.6 nM。
- GC14003 VU 0155041 sodium salt A selective positive allosteric modulator of mGluR4
- GC14097 LY 487379 hydrochloride LY 487379 hydrochloride 是一种选择性人 mGluR2 正变构调节剂 (PAM)。
- GC12699 (±)-LY 395756 ligand for mGlu2 and mGlu3 receptor
- GC17531 Z-Cyclopentyl-AP4 Group III mGlu receptor agonist
- GC15198 VU 0155041 A selective positive allosteric modulator of mGluR4
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GC10605
LY 354740
(1S,2S,5R,6S)-2-氨基二环[3.1.0]己烷-2,6-二羧酸,LY354740; Eglumetad
An agonist of mGluR2 and mGluR3 -
GC10422
CDPPB
3-氰基-N-(1,3-二苯基吡唑-5-基)苯甲酰胺
A positive allosteric modulator of mGluR5 - GC16068 A 841720 An mGluR1 antagonist
- GC11704 Ro 64-5229 mGlu2 antagonist
- GC14861 LY 379268 A selective group II mGlu2/3 receptor agonist
- GC15566 YM 298198 hydrochloride A non-competitive antagonist of mGluR1
- GC13120 Desmethyl-YM 298198 mGlu1-selective antagonist
- GC17492 LY 456236 hydrochloride mGlu1 receptor antagonist
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GC11766
Fenobam
非诺班
A noncompetitive antagonist and inverse agonist of mGluR5 - GC11287 AMN 082 dihydrochloride An allosteric mGluR7 agonist
- GC17217 JNJ 16259685 An antagonist of mGluR1a