Home >> Signaling Pathways >> Proteases >> MMP

MMP(基质金属蛋白酶)

Matrix metalloproteinases (MMPs) are a family of zinc-dependent neutral endopeptidases, generally consisting of a single peptide, a propeptide domain, a catalytic domain with a highly conserved zinc-binding site and a haemopexin-like domain, that catalyze the degradation of all components of the extracellular matrix. Multiple studies have shown that MMPs are overexpressed in malignant tumor and involved in the process of tumor growth, invasion and metastasis. Thus, synthetic and naturally occurring MMP inhibitions have been investigated as anti-cancer agents for the treatment of a variety of cancers, which are divided into three pharmacologic categories, including collagen peptidomimetics and nonpeptidomimetics, tetracycline derivatives and bisphosphonates.

  1. Cat.No. 产品名称 Information
  2. GP26168 MMP9 Mouse MMP9 Mouse produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 711 amino acids (20-730 a
  3. GP26167 MMP2 Mouse MMP2 Mouse produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 644 amino acids (30-662 aa) and having a molecular mass of 72
  4. GC67947 Triolein 13C3
  5. GC65957 MMP13-IN-2
  6. GC64992 YH-306
  7. GC64535 (S,S)-TAPI-1 A TACE inhibitor
  8. GC63661 Aderbasib
  9. GC63621 Doxycycline Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum) is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. Doxycycline is also a nonspecific matrix metalloproteinase (MMP) inhibitor.
  10. GC63322 MMP13-IN-3 An inhibitor of MMP-13
  11. GC63132 Otaplimastat
  12. GC62948 Edaravone D5
  13. GC49142 Isorhoifolin A flavonoid glycoside with diverse biological activities
  14. GC62347 CMC2.24
  15. GC48421 GW 280264X An ADAM17/TACE and ADAM10 inhibitor
  16. GC48416 Chlorhexidine-d8 (hydrochloride) An internal standard for the quantification of chlorhexidine
  17. GC48093 Spiromesifen An insecticide and acaricide
  18. GC48060 Rosuvastatin-d6 (sodium salt) An internal standard for the quantification of rosuvastatin
  19. GC47965 Pomalidomide-d5 An internal standard for the quantification of pomalidomide
  20. GC47847 Oxamyl A carbamate pesticide
  21. GC47712 Mycophenolate Mofetil-d4 An internal standard for the quantification of mycophenolate mofetil
  22. GC47660 Methyl Parathion An organophosphate insecticide
  23. GC47650 Methotrexate-d3 An internal standard for the quantification of methotrexate
  24. GC47648 Methomyl A carbamate insecticide
  25. GC47647 Methiocarb-d3 An internal standard for the quantification of methiocarb
  26. GC47646 Methiocarb A carbamate pesticide
  27. GC47366 Flurbiprofen-d3 An internal standard for the quantification of flurbiprofen
  28. GC47351 Fingolimod-d4 An internal standard for the quantification of fingolimod
  29. GC47339 Fenpropimorph A fungicide that inhibits the sterol pathway
  30. GC47326 Etoxazole An organofluorine acaricide
  31. GC47117 Colchicine-d6 An internal standard for the quantification of colchicine
  32. GC47042 Carfilzomib-d8 An internal standard for the quantification of carfilzomib
  33. GC47038 Carbofuran A carbamate insecticide
  34. GC46890 Atorvastatin-d5 (calcium salt) An internal standard for the quantification of atorvastatin
  35. GC46854 Anastrozole-d12 An internal standard for the quantification of anastrozole
  36. GC46820 AHU377-d4 An internal standard for the quantification of AHU377
  37. GC46779 Acequinocyl A naphthoquinone acaricide
  38. GC46769 Abametapir A building block and an insecticide
  39. GC60860 FSL-1 TFA FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection.
  40. GC60114 CTTHWGFTLC, CYCLIC TFA
  41. GC39640 GPLGIAGQ TFA
  42. GC50353 T 26c disodium salt A selective inhibitor of MMP-13
  43. GC50189 TAPI 0 TAPI 0 是一种 TACE(TNF-α 转化酶;ADAM17)抑制剂,IC50 为 100 nM。
  44. GC46220 SD 2590 (hydrochloride) An MMP inhibitor
  45. GC39134 Isofraxidin Isofraxidin (6,8-Dimethoxyumbelliferone), a bioactive coumarin compound isolated from the functional foods Siberian ginseng and Apium graveolens, is an anti-bacterial, anti-oxidant, and anti-inflammatory agent.
  46. GC39095 Isoliquiritin apioside Isoliquiritin apioside (ISLA, ILA), a component isolated from Glycyrrhizae radix rhizome (GR), significantly decreases PMA-induced increases in matrix metalloproteinase (MMP) activities and suppresses PMA-induced activation of mitogen-activated protein kinase (MAPK) and NF-κB. Isoliquiritin apioside possesses anti-metastatic and anti-angiogenic abilities in malignant cancer cells and ECs, with no cytotoxicity.
  47. GC38929 MMP-9-IN-1 MMP-9-IN-1 (OUN87710) is a specific inhibitor of matrix metalloproteinase-9 (MMP-9). MMP-9-IN-1 selectively targets the hemopexin (PEX) domain of MMP-9 with Kd of 2.1 μM.
  48. GC46026 TMI 1 An ADAM and MMP inhibitor
  49. GC45978 1,10-Phenanthroline (hydrate) A metal chelator and inhibitor of metalloproteases
  50. GC38871 XL-784 free base
  51. GC38837 Prinomastat hydrochloride An inhibitor of MMP-2, -3, -9, -13, and -14

Items 1 to 50 of 168 total

per page
  1. 1
  2. 2
  3. 3
  4. 4

Set Descending Direction