Amyloid β(β淀粉样蛋白)

Cat.No. 产品名称 Information

GC66416 β-Amyloid (22-35) (TFA)

GC66406 Aducanumab

GC66346 β-Amyloid (42-1), human TFA

GC66089 β-Amyloid (1-40) (TFA)

GC65582 Tramiprosate-d6

GC65281 Aleplasinin

GC64935 Thiethylperazine dimaleate

GC64934 Thiethylperazine

GC63502 Aβ/tau aggregation-IN-1

GC63274 β-Amyloid (1-42), (rat/mouse) (TFA)

GC63273 β-Amyloid (1-14),mouse,rat

GC63230 TML-6

GC62966 Ezeprogind disulfate

GC62834 ALZ-801

GC62702 RAGE antagonist peptide TFA

GC61887 Cl-NQTrp

GC61476 Fmoc-Ala-Glu-Asn-Lys-NH2

GC50733 Davunetide A neuroprotective ADNP-derived peptide

GC39254 Anatabine dicitrate

GC38628 Licochalcone B Licochalcone B (Lico B), extracted from Glycyrrhiza uralensis Fisch, induces the cell cycle arrest and apoptosis in human hepatoma cell HepG2. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction.

GA20736 Amyloid β-Protein (1-43) 淀粉样蛋白 β-Protein (1-43) 比久负盛名的 Aβ1-42 更容易聚集并具有更高的毒性。

GA20735 Amyloid β-Protein (1-42) For a detailed description of Aβ 1-42, please see product H-1368. For the preparation of Aβ for experimental use, Fezoui et al. (2000) found that solvation of synthetic peptide with sodium hydroxide (Aβ.NaOH) followed by lyophilization, produced stocks with superior solubility and fibrillogenesis characteristics. Solubilization of the pretreated material with neutral buffers resulted in a pH transition from ≈10.5 to neutral, avoiding the isoelectric point of Aβ (pI≈5.5), at which Aβ precipitation and aggregation propensity are maximal.

GA20734 Amyloid β-Protein (1-42)

GA20733 Amyloid β-Protein (1-42) 与内盐相比，Aβ42 的盐酸盐在 pH 7.4 时更容易聚集。

GA20732 Amyloid β-Protein (1-42) Aβ 1-42, 42-residue fragment of amyloid precursor protein, has been found to be a major constituent of the senile plaques formed in the brains of patients with Alzheimer's disease and late Down's syndrome. Aβ 1-42 readily forms neurotoxic oligomers at physiological pH. On the other hand, the peptide shows antimicrobial activity. The sequence of H-1368 corresponds to the human, bovine, canine, feline, ovine, guinea pig, and rabbit Aβ42 peptide. The peptide has been used to detect amyloid β-protein multimers in the cerebrospinal fluid of Alzheimer's disease patients through fluorescence correlation spectroscopy. For detailed descriptions of the preparation of Aβ 1-42 monomers and protofibrils please see the papers of Jan, Hartley, and Lashuel, Stine et al. (2011), and of Broersen and colleagues. The findings of Ryan et al. indicate that 10% ammonia disaggregates Aβ42 more efficiently than HFIP.

GA20730 Amyloid β-Protein (1-42) (HFIP-treated) H-7442 是通过将淀粉样蛋白 β-蛋白质 (1-42) (H-1368) 溶解在 HFIP 中，等分并去除溶剂而获得的，如文献中所述。

GC37997 β-Amyloid 4-10

GC37996 β-Amyloid 35-42

GC37995 β-Amyloid 33-40

GC37994 β-Amyloid 22-40

GC37993 β-Amyloid 1-9

GC37992 β-Amyloid 18-28

GC37991 β-Amyloid 15-21

GC37988 β-Amyloid 12-20

GC37987 β-Amyloid 1-20

GC37986 β-Amyloid 1-17

GC37985 β-Amyloid 11-22

GC37984 β-Amyloid (1-42), rat

GC37639 Silybin B

GC37624 Semilicoisoflavone B

GC37610 Scyllo-Inositol A stereoisomer of inositol

GC36954 PQM130

GC36247 Hoechst 34580 tetrahydrochloride Hoechst 34580 (HOE 34580) is a cell-permeable blue fluorescent dye to stain DNA and nuclei. Hoechst 34580 is also a good candidate for treating the Alzheimer's disease by inhibiting amyloid beta (Aβ) formation with IC50 of 0.86 μM.

GC36156 Glutaminyl Cyclase Inhibitor 3

GC36110 gamma-Secretase Modulators

GC36076 Frentizole Frentizole (Frentizol) is a novel inhibitor of amyloid beta peptide (Abeta) binding alcohol dehydrogenase (ABAD) interaction with IC50 of 200 μM. Frentizole is a nontoxic antiviral and immunosuppressive agent used clinically in rheumatoid arthritis and systemic lupus erythematosus.

GC35720 Colivelin TFA A potent STAT3 activator and neuroprotective agent

GC35334 Amyloid β Peptide (42-1)(human)

GC44856 Rutin (hydrate) A flavonoid glycoside with diverse biological activities

GC34242 β-Amyloid (1-42), rat TFA