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Home >> Signaling Pathways >> Neuroscience >> Amyloid β

Amyloid β(β淀粉样蛋白)

Amyloid β denotes peptides of 36–43 amino acids result from the APP (amyloid precursor protein) and are involved in Alzheimer's disease as the main component of the amyloid plaques.

Products for  Amyloid β

  1. Cat.No. 产品名称 Information
  2. GC36076 Frentizole Frentizole (Frentizol) is a novel inhibitor of amyloid beta peptide (Abeta) binding alcohol dehydrogenase (ABAD) interaction with IC50 of 200 μM. Frentizole is a nontoxic antiviral and immunosuppressive agent used clinically in rheumatoid arthritis and systemic lupus erythematosus.
  3. GC35720 Colivelin TFA

    A potent STAT3 activator and neuroprotective agent
  4. GC35334 Amyloid β Peptide (42-1)(human) 淀粉样蛋白 β Peptide (42-1)(human) 是淀粉样蛋白 β 的无活性形式；肽 (1-42)。
  5. GC44856 Rutin (hydrate) A flavonoid glycoside with diverse biological activities
  6. GC34242 β-Amyloid (1-42), rat TFA β-Amyloid(1-42),ratTFA是由42个氨基酸组成的多肽，对海马切片有毒性，可用于阿尔兹海默症的研究。
  7. GC34232 Beta-Amyloid(1-14),mouse,rat Beta-Amyloid(1-14),mouse,rat是Amyloid-β多肽的1-14片段。
  8. GC33750 BF-168 BF-168是PET的候选探针，能够特异性识别神经和弥漫性斑块，其对Aβ1-42的Ki值为6.4nM。
  9. GC33160 amyloid P-IN-1 amyloidP-IN-1有利于在疾病或功能失调的治疗中消耗血清淀粉样蛋白P组件(SAP)，包括淀粉样变,阿尔茨海默病，2型糖尿病和关节炎。
  10. GC31285 MK-3328 MK-3328是一种β-淀粉样蛋白(β-Amyloid)PET配体，具有高的结合效力，IC50为10.5nM。
  11. GC31259 Aftin-4 An inducer of Aβ42
  12. GC31208 4-(6-Bromo-2-benzothiazolyl)benzenamine 4-(6-Bromo-2-benzothiazolyl)benzenamine是β-淀粉样蛋白(β-amyloid)的PET（正电子发射断层扫描）示踪剂，可用于诊断神经疾病，如阿尔茨海默病和唐氏综合征。
  13. GC31179 β-Amyloid 31-35 β-Amyloid(31-35)是具有神经毒性的天然β淀粉样肽的最短序列。
  14. GC31171 β-Amyloid 1-28 (Amyloid β-Protein (1-28)) β-Amyloid 1-28 (Amyloid β-Protein (1-28)) 是 β-Amyloid 蛋白片段，参与金属结合。
  15. GC31146 β-Amyloid (10-35), amide β-Amyloid(10-35),amide是一种含有26个氨基酸的多肽，由β-Amyloid肽的10-35残基组成。β-Amyloid(10-35)是阿尔兹海默症淀粉样斑块(Alzheimer'sdisease)的主要组成成分。
  16. GC31137 β-Amyloid 29-40 (Amyloid beta-protein(29-40)) β-Amyloid 29-40 (Amyloid beta-protein(29-40)) 是 Amyloid-β 的一个片段；肽。
  17. GC31129 β-Amyloid 1-16 (Amyloid β-Protein (1-16)) β-Amyloid 1-16 (Amyloid β-Protein (1-16)) 是 ⋲-Amyloid 蛋白片段，参与金属结合。
  18. GC31124 BF 227

    BF227是PET淀粉样显像探针的一个候选，其对Aβ1-42的Ki值为4.3nM。
  19. GC31110 Glutaminyl Cyclase Inhibitor 2 GlutaminylCyclaseInhibitor2是谷氨酰胺酰基环化酶(glutaminylcyclase)抑制剂，IC50值为1.23μM。
  20. GC31083 DWK-1339 (MDR-1339) An inhibitor of amyloid-β aggregation
  21. GC30952 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine是一种有效的淀粉样蛋白显像剂，其与淀粉样蛋白Amyloid-β(1-40)结合的KD值为1.7nM。
  22. GC30920 K 01-162 (K162) K 01-162 (K162) (K162) 抑制 Aβ 的原纤维形成；肽并消除其神经毒性。
  23. GC30892 Glutaminyl Cyclase Inhibitor 1 GlutaminylCyclaseInhibitor1是谷氨酰胺酰基环化酶(glutaminylcyclase)抑制剂，IC50值为0.5μM。
  24. GC30884 LX2343 An inhibitor of BACE1 and PI3K
  25. GC30823 Edonerpic maleate (T-817 maleate)

    T-817MA is a newly synthesized agent for Alzheimer's disease (AD) treatment
  26. GC30325 β-Amyloid 22-35 (Amyloid β-Protein (22-35)) β-Amyloid 22-35 (Amyloid β-Protein 22-35), β-amyloid 的残基 22-35 片段;-淀粉样蛋白对在无血清培养基中培养的大鼠海马神经元具有细胞毒性作用。
  27. GC19053 Azeliragon An inhibitor of RAGE
  28. GC16139 (R,S)-Anatabine (tartrate) A minor tobacco alkaloid
  29. GC16032 (R,S)-Anatabine A minor tobacco alkaloid
  30. GC17007 TAE-1 A sym-triazine with diverse biological activities
  31. GC17037 NQTrp An inhibitor of Aβ oligomerization
  32. GC15105 FPS-ZM1 A high-affinity inhibitor of RAGE
  33. GC14828 CPHPC An inhibitor of the protein-protein interaction between SAP and amyloid fibrils
  34. GC13554 Deferoxamine mesylate An iron chelator and inhibitor of prolyl hydroxylases
  35. GC16243 β-Amyloid (1-42), human TFA

    Amyloid β-Peptide (1-42) human TFA is a 42-amino acid peptide.
  36. GC11309 ARN2966 An inhibitor of APP production and Aβ secretion
  37. GC10988 J 147 J 147 是一种非常有效的口服活性神经保护剂，用于增强认知能力。
  38. GC10894 Methoxy-X04

    Methoxy-X04是一种淀粉样蛋白-β（aβ）的脑透性荧光探针，用于检测和量化斑块、缠结和脑血管淀粉样蛋白。它对原纤维β-片沉积显示出高的体外结合亲和力（Ki =26.8 nM）。
  39. GC15950 CGP 52411 A phthalimide with diverse biological activities
  40. GC10425 Ro 90-7501 An antiviral useful in Alzheimer’s research
  41. GC10230 CRANAD 2 An affinity probe for amyloid-β
  42. GC12366 LPYFD-NH2 LPYFD-NH2 是一种五肽，对 Aβ(1-42) 的聚集具有一定的抑制作用。
  43. GC14854 Colivelin A potent STAT3 activator and neuroprotective agent
  44. GC17910 Tramiprosate A sulfated glycosaminoglycan mimetic
  45. GC13783 Phenserine An AChE inhibitor
  46. GC13256 Dihydroergocristine mesylate An alkaloid with diverse biological activities
  47. GC10660 EHT 1864 An inhibitor of Rac GTPases
  48. GC17974 Latrepirdine dihydrochloride A neuroprotective agent
  49. GC10089 EUK 134 A synthetic catalase/SOD mimic and hydrogen peroxide scavenger
  50. GC17657 Hoechst 34580

    The nucleic acid stain Hoechst 34580 (Ex/Em: 392/440 nm) is frequently utilized as a cell-permeable nuclear counterstain that emits a blue fluorescence upon binding to dsDNA.
  51. GC17921 Tolcapone A reversible COMT inhibitor

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