Histamine Receptor(组胺受体)

Cat.No. 产品名称 Information

GC25785 Promethazine Promethazine is a potent histamine H1 receptor antagonist. Promethazine is a medication used in the management and treatment of allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine exhibits antiparasitic properties.

GC25571 Levocetirizine Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor.

GC25136 Betazole Dihydrochloride Betazole Dihydrochloride (Ametazole, 2-(3-Pyrazolyl)ethanamine) is a histamine H2 agonist used clinically to test gastric secretory function.

GC25060 Amitriptyline Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid.

GC67995 Ketotifen-d3 fumarate

GC67944 Cetirizine D4

GC66445 Dimethindene maleate

GC65937 INCB38579

GC65296 Pimethixene maleate Pimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimethixene maleate inhibits 5-HT2A, 5-HT2B, 5-HT2C, 5-HT1A, 5-HT1B, 5-HT6, 5-HT7, Adrenergic α-1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4.4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2 with pKi of 10.22, 10.44, 8.42, 7.63, < 5, 7.30, 7.28, 7.61, 6.37, 8.19, 7.54, 10.14, 8.61 and 9.38, respectively.

GC64935 Thiethylperazine dimaleate

GC64934 Thiethylperazine

GC64661 H3R antagonist 1 hydrochloride

GC64646 Psoralenoside

GC64577 Cetirizine Impurity C dihydrochloride

GC64545 Tecastemizole

GC64088 Cyclizine A histamine H₁ receptor antagonist

GC64084 Samelisant

GC63923 Betahistine-d3 dihydrochloride An internal standard for the quantification of betahistine

GC63666 Chlorcyclizine A histamine H₁ antagonist

GC63318 Bilastine-d6

GC63312 Promethazine-d6 hydrochloride

GC62267 Cimetidine sulfoxide

GC61539 Betazole Betazole Dihydrochloride (Ametazole, 2-(3-Pyrazolyl)ethanamine) is a histamine H2 agonist used clinically to test gastric secretory function.

GC61467 Niaprazine

GC61401 Oxatomide

GC48892 NSC 19005 A potential impurity found in commercial preparations of betahistine

GC48855 Mirtazapine (CRM) An Analytical Reference Material

GC48835 Diphenylpyraline A histamine H₁ receptor antagonist

GC61256 Rupatadine D4 fumarate

GC60924 Hydroxyzine D8 An internal standard for the quantification of hydroxyzine

GC60791 Doxepin D3 Hydrochloride

GC60709 Cinnarizine D8 An internal standard for the quantification of cinnarizine

GC60691 Cetirizine Impurity C

GC60641 Betahistine mesylate Betahistine mesylate is the mesylate salt form of Betahistine, a histamine analog and H3 receptor agonist that serves as a vasodilator.

GC60563 Acrivastine D7

GC60072 Betahistine A histamine H₃ receptor antagonist and histamine H₁ receptor agonist

GC39735 Triprolidine hydrochloride monohydrate Triprolidine Hydrochloride is the hydrochloride salt form of Triprolidine, which is the first generation histamine H1 antagonist used in allergic rhinitis.

GC39479 Bepotastine A histamine H₁ receptor antagonist

GC39378 Emedastine A histamine H₁ receptor antagonist

GC50405 JNJ 39758979 dihydrochloride 高亲和力和选择性组胺H4拮抗剂；口服生物利用度

GC46185 Nimbin A limonoid with diverse biological activities

GC38558 PF-03654746 Tosylate

GC38450 LML134

GC37959 Zaltidine

GC36932 Pitolisant oxalate A histamine H₃ receptor antagonist and inverse agonist

GC36931 Pitolisant A histamine H₃ receptor antagonist and inverse agonist

GC36878 PF-03654746

GC36875 Perphenazine D8 Dihydrochloride

GC36476 Lodoxamide tromethamine A potent agonist of GPR35 and a mast cell stabilizer

GC36279 Hydroxyzine pamoate Hydroxyzine Pamoate is the pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties.