Histamine Receptor(组胺受体)
Histamine receptor has 4 subtypes (H1,H2,H3 and H4) which mediates various biological fuctions, including allergic reaction, gastric acid secretion and inflammation etc.
- Cat.No. 产品名称 Information
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GC25785
Promethazine
Promethazine is a potent histamine H1 receptor antagonist. Promethazine is a medication used in the management and treatment of allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine exhibits antiparasitic properties.
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GC25571
Levocetirizine
Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor.
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GC25136
Betazole Dihydrochloride
Betazole Dihydrochloride (Ametazole, 2-(3-Pyrazolyl)ethanamine) is a histamine H2 agonist used clinically to test gastric secretory function.
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GC25060
Amitriptyline
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid.
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GC67995
Ketotifen-d3 fumarate
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GC67944
Cetirizine D4
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GC66445
Dimethindene maleate
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GC65937
INCB38579
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GC65296
Pimethixene maleate
Pimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimethixene maleate inhibits 5-HT2A, 5-HT2B, 5-HT2C, 5-HT1A, 5-HT1B, 5-HT6, 5-HT7, Adrenergic α-1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4.4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2 with pKi of 10.22, 10.44, 8.42, 7.63, < 5, 7.30, 7.28, 7.61, 6.37, 8.19, 7.54, 10.14, 8.61 and 9.38, respectively.
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GC64935
Thiethylperazine dimaleate
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GC64934
Thiethylperazine
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GC64661
H3R antagonist 1 hydrochloride
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GC64646
Psoralenoside
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GC64577
Cetirizine Impurity C dihydrochloride
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GC64545
Tecastemizole
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GC64088
Cyclizine
A histamine H1 receptor antagonist
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GC64084
Samelisant
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GC63923
Betahistine-d3 dihydrochloride
An internal standard for the quantification of betahistine
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GC63666
Chlorcyclizine
A histamine H1 antagonist
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GC63318
Bilastine-d6
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GC63312
Promethazine-d6 hydrochloride
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GC62267
Cimetidine sulfoxide
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GC61539
Betazole
Betazole Dihydrochloride (Ametazole, 2-(3-Pyrazolyl)ethanamine) is a histamine H2 agonist used clinically to test gastric secretory function.
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GC61467
Niaprazine
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GC61401
Oxatomide
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GC48892
NSC 19005
A potential impurity found in commercial preparations of betahistine
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GC48855
Mirtazapine (CRM)
An Analytical Reference Material
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GC48835
Diphenylpyraline
A histamine H1 receptor antagonist
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GC61256
Rupatadine D4 fumarate
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GC60924
Hydroxyzine D8
An internal standard for the quantification of hydroxyzine
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GC60791
Doxepin D3 Hydrochloride
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GC60709
Cinnarizine D8
An internal standard for the quantification of cinnarizine
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GC60691
Cetirizine Impurity C
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GC60641
Betahistine mesylate
Betahistine mesylate is the mesylate salt form of Betahistine, a histamine analog and H3 receptor agonist that serves as a vasodilator.
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GC60563
Acrivastine D7
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GC60072
Betahistine
A histamine H3 receptor antagonist and histamine H1 receptor agonist
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GC39735
Triprolidine hydrochloride monohydrate
Triprolidine Hydrochloride is the hydrochloride salt form of Triprolidine, which is the first generation histamine H1 antagonist used in allergic rhinitis.
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GC39479
Bepotastine
A histamine H1 receptor antagonist
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GC39378
Emedastine
A histamine H1 receptor antagonist
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GC50405
JNJ 39758979 dihydrochloride
高亲和力和选择性组胺H4拮抗剂;口服生物利用度
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GC46185
Nimbin
A limonoid with diverse biological activities
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GC38558
PF-03654746 Tosylate
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GC38450
LML134
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GC37959
Zaltidine
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GC36932
Pitolisant oxalate
A histamine H3 receptor antagonist and inverse agonist
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GC36931
Pitolisant
A histamine H3 receptor antagonist and inverse agonist
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GC36878
PF-03654746
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GC36875
Perphenazine D8 Dihydrochloride
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GC36476
Lodoxamide tromethamine
A potent agonist of GPR35 and a mast cell stabilizer
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GC36279
Hydroxyzine pamoate
Hydroxyzine Pamoate is the pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties.