GPCR/G protein(G 蛋白偶联受体/G 蛋白)

Cat.No. 产品名称 Information

GC48870 Anagrelide-13C3

BL 4162A-13C3, BMY 26538-01-13C3

An internal standard for the quantification of anagrelide

GC48513 Quinapril-d5

[2H5]-喹那普利

An internal standard for the quantification of quinapril

GC48509 Apigenin 7-O-Glucuronide (hydrate) Apigenin 7-O-glucuronide is a flavonoid that has been found in J

GC48494 BIBP3226 A nonpeptide antagonist of NPY receptor Y₁

GC50742 Chemerin-9, Mouse Chemokine-like receptor 1 (CMKLR1) agonist (EC50 = 42 nM)

GC50741 BIIE 0246 hydrochloride Potent, selective and competitive nonpeptide antagonist for the neuropeptide Y Y2 receptor (IC50 = 15 nM)

GC50722 ER 819762 ER 817692 是一种具有口服活性的高选择性前列腺素 E2 (PGE2) EP4 受体拮抗剂，对人 EP4 受体的 EC50 为 70 nM。

GC50717 PKRA 7 Potent prokineticin (PK) receptor antagonist (IC50 values are 5

GC50711 ML 339 Potent and selective hCXCR6 antagonist (IC50 = 140 nM); 100-fold less active at the murine CXCR6 receptor (IC50 = 18 μM)

GC50695 ABT 702 hydrochloride Potent non-nucleoside adenosine kinase inhibitor (IC50 = 1

GC50682 JHU 37160 JHU 37160 是一种有效的脑渗透性 DREADD 激动剂，在 HEK-293 细胞中对 hM3Dq 和 hM4Di DREADD 的 EC50 分别为 18.5 nM 和 0.2 nM。

GC50681 JHU 37152 JHU 37152 是一种有效的脑渗透性 DREADD 激动剂，在 HEK-293 细胞中对 hM3Dq 和 hM4Di DREADD 的 EC50 分别为 5 nM 和 0.5 nM。

GC50679 ISAM 140 ISAM 140 (22b) 是一种有效且高度选择性的 A2B 腺苷受体拮抗剂，Ki 为 3.49 nM。

GC50668 PF 04479745 PF 04479745 是一种有效的选择性 5-HT2C 受体激动剂（EC50:10 nM，ki:15 nM）。 PF 04479745 可用于高血压等心血管疾病的研究。

GC50662 DL 175 Potent and selective GPR84 biased agonist (EC50 = 33 nM)

GC50655 AZ 10397767 Potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin-induced NF-κB activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells

GC48269 Zilpaterol-d7

齐帕特罗-D7

An internal standard for the quantification of zilpaterol

GC48262 YM-90K (hydrochloride hydrate) A neuropeptide with diverse biological activities

GC48255 Vortioxetine-d8

Lu AA 21004 D8

An internal standard for the quantification of vortioxetine

GC48246 VCP171 A positive allosteric modulator of adenosine A₁ receptors

GC48243 Vardenafil-d5

伐地那非-d5杂质17

An internal standard for the quantification of vardenafil

GC48121 Tadalafil-d3

他达拉非-D3,IC-351-d3

An internal standard for the quantification of tadalafil

GC48078 Sildenafil-d3

西地那非-D3,UK-92480-d3

An internal standard for the quantification of sildenafil

GC48067 Salmeterol-d3

沙美特罗-D3

An internal standard for the quantification of salmeterol

GC47923 Paraxanthine-d6

1,7-Dimethylxanthine-d6

An internal standard for the quantification of paraxanthine

GC47866 Palmitoyl Ethanolamide-d5

Palmidrold5, PEA15,15,16,16,16d5

A neuropeptide with diverse biological activities

GC47742 Naled

二溴磷

An organophosphate insecticide and acaricide

GC47645 Methidathion

杀扑磷

An organophosphate insecticide

GC47438 H-Val-Pro-Pro-OH (trifluoroactetate salt)

VPP

A neuropeptide with diverse biological activities

GC47371 Fosinopril-d7 (sodium salt) An internal standard for the quantification of fosinopril

GC47314 Ethopropazine (hydrochloride)

盐酸乙丙嗪,Isothazine hydrochloride; Lysivane hydrochloride; Parsidol hydrochloride

A BChE inhibitor

GC47263 Donecopride (fumarate hydrate)

MR31147

A 5-HT₄ receptor partial agonist and AChE inhibitor

GC47237 Dipyridamole-d16 A neuropeptide with diverse biological activities

GC47211 Dichlorvos

敌敌畏

An organophosphate insecticide

GC47186 Deoxy Donepezil (hydrochloride)

1-苄基-4-((5,6-二甲氧基-2,3-二氢-1H-茚-2-基)甲基)哌啶盐酸盐

A potential impurity found in bulk preparations of donepezil

GC47122 Coumaphos

蝇毒磷

An organophosphate pesticide

GC47088 Cilostazol-d4

西洛他唑-D4,OPC-13013-d4

An internal standard for the quantification of cilostazol

GC46915 Bendiocarb

恶虫威

A broad-spectrum carbamate insecticide

GC46913 Benazepril-d5 (hydrochloride)

贝那普利杂质,CGS14824A-d5 hydrochloride

An internal standard for the quantification of benazapril

GC46898 Avanafil-13C-d3

TA1790-13C,d3

A neuropeptide with diverse biological activities

GC46893 Atranorin

荔枝素

A depside lichen metabolite with diverse biological activities

GC46283 (±)-Clorprenaline-d7

Isoprophenamine-d7

A neuropeptide with diverse biological activities

GC61389 Ziprasidone amino acid

齐拉西酮开环物,氨基酸杂质,Ziprasidone Impurity C; Ziprasidone open ring impurity

Ziprasidoneaminoacid(ZiprasidoneImpurityC)是Ziprasidone的杂质。Ziprasidone是5-HT和多巴胺(dopaminereceptor)受体拮抗剂，具有抗精神病活性。

GC61387 Zamifenacin

UK-76654

A muscarinic M₃ receptor antagonist

GC61378 VU0238441 VU0238441 is a pan muscarinic acetylcholine receptor (mAChR) positive allosteric modulator (PAM) with EC50 of 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and >10 μM for M5, M3, M2, M1 and M4, respectively.