GPCR/G protein(G 蛋白偶联受体/G 蛋白)
- Neuropeptide FF/AF Receptors(49)
- Formyl Peptide Receptors(10)
- 5-HT Receptor(482)
- Acetylcholine(28)
- Adenosine Deaminase(9)
- Adenosine Receptor(130)
- Adenosine Kinase(4)
- Adiponectin Receptor(3)
- Adrenergic Receptor(407)
- Adrenergic Transporters(5)
- Apelin Receptor(9)
- Angiotensin Receptor(111)
- Bombesin Receptors(23)
- Bradykinin Receptors(29)
- Calcitonin and Related Receptors(10)
- Cannabinoid Receptor(118)
- Calcimimetic Agent(2)
- CaSR(20)
- CCK1 Receptors(7)
- CCK2 Receptors(7)
- CCR(80)
- Chemokine Receptors(23)
- CRF1 Receptors(9)
- CRF2 Receptors(3)
- CXCR(77)
- CysLT1 receptor(1)
- Endothelin Receptor(50)
- EP1 Receptor(2)
- EP4 Receptor(2)
- ERRγ(1)
- ETA Receptors(5)
- ETB Receptors(5)
- Free Fatty Acid Receptors(16)
- Galanin Receptors(11)
- Ghrelin Receptors(11)
- GHSR(19)
- GIP Receptor(5)
- Glucagon Receptor(58)
- Glucocorticoid Receptor(96)
- GLUT1(1)
- Gonadotropin-Releasing Hormone Receptors(3)
- GPCR19(12)
- GPR109A(4)
- GPR119(10)
- GPR120(9)
- GPR35(10)
- GPR55(10)
- Hydroxycarboxylic Acid Receptors(5)
- Leukotriene Receptor(55)
- LPA Receptor(12)
- LPL Receptor(59)
- LTD4 Receptor(1)
- mGluR (119)
- Melanin-concentrating Hormone Receptors(7)
- Melanocortin (MC) Receptors(54)
- Melatonin Receptors(23)
- Motilin Receptor(7)
- MT Receptor(1)
- Non-selective CRF(7)
- Neurotensin Receptors(23)
- NK2 Receptors(7)
- NK3 Receptor(5)
- NOP Receptor(19)
- NPY Receptors(26)
- Orexin(3)
- Orphan 7-TM Receptors(6)
- OX Receptor(47)
- Oxytocin Receptors(22)
- P2Y Receptor(60)
- PACAP Receptors(3)
- PAF Receptors(7)
- Peptide Receptors(14)
- PGD2 Receptor(1)
- Prostaglandin Receptor(170)
- Protease-Activated Receptors(9)
- RGS(2)
- S1P receptor(8)
- Secretin Receptors(1)
- Sensory Neuron-Specific Receptors(1)
- Somatostatin Receptor(39)
- Sigma Receptor(58)
- Vasopressin Receptor(33)
- 17,20-lyase(4)
- Ras(138)
- Urotensin-II Receptor(10)
- VIP Receptors(6)
- EBI2/GPR183(7)
- TSH Receptor(10)
- NK Receptor(1)
- GPR81(1)
- C3aR(1)
- CysLT2 receptor(1)
- S1P receptor inhibitor(22)
- CCKB(1)
- FFAR1 (GPR40)(20)
- GPR84(8)
- Neuromedin U Receptors(2)
- Kisspeptin Receptor(5)
- CRFR(25)
- RGS Protein(5)
- Urotensin Receptor(6)
- Cholecystokinin Receptor(25)
- GPR139(4)
- mAChR(183)
- MCHR1 (GPR24)(16)
- Neurokinin Receptor(75)
- Neuropeptide S Receptor(1)
- GPBA Receptor(1)
- Trace Amine 1 Receptor(2)
- GPCR protein(1)
- FFAR3(1)
- cGMP(26)
- GRK(1)
- GCGR(2)
- GLP Receptor(2)
- PTHR(1)
- Protease Activated Receptor (PAR)(2)
- Free Fatty Acid Receptor(1)
- Formyl Peptide Receptor (FPR)(1)
- Cat.No. 产品名称 Information
-
GC14033
ICI 118,551 hydrochloride
ICI 118551 hydrochloride
A potent, selective β2-adrenergic receptor antagonist -
GC11637
Mifepristone
米非司酮; RU486; RU 38486
Mifepristone (RU486)是一种口服有效的孕酮(PR)受体和糖皮质激素受体(GR)拮抗剂,用作堕胎药物,体外实验中IC50值分别为0.2nM和2.6nM。 -
GC11897
Budesonide
布地奈德
A glucocorticoid and an agonist of glucocorticoid receptors -
GC17465
Beclomethasone dipropionate
丙酸倍氯米松
Corticosteroid used for asthma and rhinitis -
GC10936
Betamethasone
倍他米松
A synthetic corticosteroid -
GC16819
VU0152100
3-氨基-N-[(4-甲氧基苯基)甲基]-4,6-二甲基噻吩并[2,3-B]吡啶-2-甲酰胺,VU152100
A muscarinic M4 receptor positive allosteric modulator -
GC11006
Montelukast Sodium
孟鲁司特钠; MK0476
A CysLT1 receptor antagonist -
GC10664
Org 27569
ORG275695-氯-3-乙基-N-[2-[4-(1-哌啶基)苯基]乙基-1H-吲哚-2-甲酰胺
Org 27569 是一种有效的 CB1 受体变构调节剂,可增加激动剂的结合,但阻断激动剂诱导的 CB1 信号传导。 -
GC17130
BRL-54443
3-(1-甲基-4-哌啶基)-1H-吲哚-5-醇
A potent agonist of 5-HT1E and 5-HT1F -
GC17184
Ambrisentan
安倍生坦; BSF 208075; LU 208075
An ETA receptor antagonist -
GC10621
Biperiden HCl
盐酸比哌立登; KL 373 hydrochloride
A muscarinic acetylcholine receptor antagonist
-
GC11978
CGS 21680 HCl
CGS 21680 HCl是一种选择性腺苷A2A受体激动剂,IC50值为22nM。
-
GC16226
BRL-15572 dihydrochloride
BRL15572盐酸盐
A 5-HT1D receptor antagonist -
GC11078
MRS 2578
A selective antagonist of the purinergic P2Y6 receptor
-
GC17769
Sitaxentan sodium
西他生坦钠,IPI 1040 sodium; TBC11251 sodium
Sitaxentan sodium是一种选择性内皮素A受体(ETA)拮抗剂(IC50 = 1.4nM;Ki = 0.43nM)。 -
GC10609
GSK962040 hydrochloride
GSK962040 hydrochloride
GSK962040 hydrochloride (GSK962040 hydrochloride) 是一种小分子选择性胃动素受体激动剂,pEC50 为 7.9。 -
GC16491
GSK962040
GSK962040
GSK962040 (GSK962040) 是一种小分子选择性胃动素受体激动剂,pEC50 为 7.9。 -
GC17807
TCS 1102
A dual orexin receptor antagonist
-
GC13539
SB-334867
SB 334867A
An orexin 1 receptor antagonist -
GC15653
PF-05212384 (PKI-587)
N-[4-[[4-(二甲基氨基)-1-哌啶基]羰基]苯基]-N'-[4-[4,6-二(4-吗啉基)-1,3,5-三嗪-2-基]苯基]脲,PKI-587; PF-05212384
A potent, dual PI3K/mTOR inhibitor -
GC17414
Palosuran
ACT-058362
A urotensin II receptor antagonist -
GC16394
PD123319
(S)-(+)-PD 123319
PD123319 是血管紧张素 II 受体的非肽类抑制剂,IC50 值为 34nM 。 -
GC15332
Ticagrelor
替卡格雷; AZD6140; AR-C 126532XX
A reversible purinergic P2Y12 receptor antagonist -
GC16943
NPS-2143
2-氯-6-[(2R)-3-[[1,1-二甲基-2-(2-萘基)乙基]氨基]-2-羟基丙氧基]苯腈,SB-262470A
NPS-2143 是一种钙化药物,可作为钙敏感受体 (CaSR) 的拮抗剂,从而刺激甲状旁腺激素的释放。 -
GC10264
Arecoline hydrobromide
氢溴酸槟榔碱
Muscarinic acetylcholine receptor agonist -
GC12073
Xylazine
赛拉嗪,BAY 1470
Xylazine(赛拉嗪;BAY 1470)是一种有效的α2-肾上腺素受体的强激动剂,在兽医学中广泛用作镇静剂,还能诱导肌肉松弛。
-
GC15631
Sotalol hydrochloride
盐酸索他洛尔; MJ 1999
A β-AR antagonist and a class III antiarrhythmic agent -
GC13085
Terazosin
特拉唑嗪
A potent and selective α1-AR antagonist -
GC10698
Cyproheptadine hydrochloride
盐酸赛庚啶
An antihistamine with antiserotonergic and anticholinergic activities -
GC13236
ACT-132577
N-[5-(4-溴苯基)-6-[2-[(5-溴-2-嘧啶基)氧基]乙氧基]-4-嘧啶基]氨基磺酰胺,ACT-132577
A dual ETA and ETB receptor antagonist and an active metabolite of macitentan -
GC15916
BQ-788 sodium salt
BQ-788钠盐
A peptide ETB receptor antagonist -
GC14944
AR 231453
An agonist of GPR119
-
GC11939
AMG 487
(±)-AMG 487
A CXCR3 antagonist
-
GC15222
Siramesine hydrochloride
西拉美新盐酸盐; Lu 28-179 hydrochloride
Siramesine hydrochloride是一种有效的sigma-2受体激动剂。Siramesine对sigma-2受体具有亚纳摩尔亲和力 (IC50=0.12nM),并且对sigma-2受体的选择性是sigma-1受体的140倍(IC50=17nM)。 -
GC10050
Almorexant hydrochloride
阿莫伦特盐酸盐,ACT 078573 hydrochloride
An orexin 1 and orexin 2 receptor antagonist -
GC10717
Almorexant
阿莫伦特; ACT 078573
Almorexant (ACT 078573) 是一种具有口服活性、强效和竞争性的双重食欲素受体拮抗剂,Kd 值分别为 1.3 nM (OX1) 和 0.17 nM (OX2)。 -
GC16701
SKI II
鞘氨醇激酶抑制剂
An SPHK1 inhibitor -
GC10030
EHop-016
A Rac1 and Rac3 inhibitor
-
GC17201
BAF312 (Siponimod)
辛波莫德; BAF-312
An S1P1 and S1P5 receptor agonist receptor modulator -
GC14807
Fingolimod (FTY720) HCl
盐酸芬戈莫德; FTY720
芬戈莫德(FTY720)是一种免疫抑制剂,通常用于治疗多发性硬化症,也有抗癌作用,可以作为HDACi(组蛋白脱乙酰酶抑制剂)。 -
GC12611
Triamcinolone Acetonide
曲安奈德
A synthetic corticosteroid -
GC11915
Mirabegron (YM178)
米拉贝隆; YM178
A β3-AR agonist -
GC12717
Ipratropium Bromide
异丙托溴铵; Sch 1000
A muscarinic receptor antagonist -
GC13871
Duloxetine HCl
盐酸度洛西汀; (S)-Duloxetine hydrochloride; LY-248686 hydrochloride
A serotonin and norepinephrine reuptake inhibitor -
GC16635
Diphemanil Methylsulfate
甲硫二苯马尼,Diphemanil mesylate
An anticholinergic agent -
GC12627
Conivaptan HCl
盐酸考尼伐坦; YM 087
A vasopressin V1A and V2 receptor antagonist -
GC13638
Betamethasone Valerate
倍他米松戊酸酯,Betamethasone 17-valerate
A glucocorticoid with anti-inflammatory activity -
GC12122
Betamethasone Dipropionate
二丙酸倍他米松; Betamethasone 17,21-dipropionate
倍他米松二丙酸酯是一种糖皮质激素类固醇,具有抗炎和免疫抑制能力。 -
GC14160
Blonanserin
布南色林; AD-5423
A dopamine and serotonin receptor antagonist -
GC11977
Thioridazine HCl
盐酸硫利达嗪;盐酸硫代利哒;甲硫达嗪盐酸盐;甲硫哒嗪盐酸盐
A typical antipsychotic