JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

Home >> Signaling Pathways >> GPCR/G protein

GPCR/G protein(G 蛋白偶联受体/G 蛋白)

Cat.No. 产品名称 Information
GC15367 EMDT oxalate EMDT 草酸盐是一种选择性 5-HT6 激动剂，具有抗抑郁作用。
GC12018 AS 1269574 Agonist of GPR119
GC10051 MDL 100907
MDL100907; M 100907
Selective antagonist of the serotonin receptor 5-HT_2A
GC17174 ML 145 An antagonist of GPR35
GC10674 LY 266097 hydrochloride A 5-HT_2B receptor antagonist
GC15788 MJ 15 A potent CB₁ receptor antagonist
GC12510 BINA
3'-[[(2-环戊基-6,7-二甲基-1-氧代-2,3-二氢-1H-茚-5-基)氧基]甲基]联苯-4-羧酸,BINA
A positive allosteric modulator of mGluR2
GC14088 Zotepine
佐替平
An atypical antipsychotic
GC15872 NPEC-caged-serotonin
5-HT receptor agonist
GC15704 NPEC-caged-noradrenalin Adrenergic receptor agonist
GC16091 SR 58611A hydrochloride
SR 58611A
A selective β₃-AR agonist
GC10903 YIL 781
An antagonist of GHS-R1a
GC16159 ANR 94 ANR 94 是一种有效的选择性腺苷 A2A 受体 (AA2AR) 拮抗剂，对 hAA2AR 的 Ki 值为 46 nM。
GC10622 OPC 21268
N-[3-[4-[[4-(3,4-二氢-2-氧代-1(2H)-喹啉基)-1-哌啶基]羰基]苯氧基]丙基]乙酰胺,OPC-21268
A nonpeptide antagonist of vasopressin V₁ receptors
GC13267 NIDA 41020 A CB₁ receptor antagonist
GC17142 SF 11 An antagonist of NPY receptor Y₂
GC13221 NF 546 NF 546 是一种选择性非核苷酸 P2Y11 激动剂，pEC50 为 6.27。
GC15144 (±)-PPCC oxalate
(1R,2S)-REL-2-[(4-羟基-4-苯基-1-哌啶基)甲基]-1-(4-甲基苯基)环丙烷羧酸甲酯
sigma (σ) receptor ligand
GC12856 SKF 86466 hydrochloride An α₂-AR antagonist
GC17700 R 568 hydrochloride
2-氯-N-[(1R)-1-(3-甲氧基苯基)乙基]苯丙胺盐酸盐,R-568 hydrochloride
A calcimimetic and positive allosteric modulator of CaSR
GC10922 TUG 424 A selective FFAR1 (GPR40) agonist
GC11802 CP 135807
3-[[(2R)-1-甲基-2-吡咯]甲基-N-(3-硝基-2-吡啶基)-1H-吲哚-5-胺
5-HT1D receptor agonist
GC13165 SC 51089
CID132748
Selective EP₁ antagonist
GC13242 SR 48692
2-[[[1-(7-氯-4-喹啉基)-5-(2,6-二甲氧基苯基)-1H-吡唑-3-基]羰基]氨基]-金刚烷-2-羧酸
An allosteric antagonist of NTS₁
GC17963 CHPG Sodium salt CHPG 钠盐是一种选择性 mGluR5 激动剂，可通过 BV2 小胶质细胞中的 TSG-6/NF-κB 通路减弱 SO2 诱导的氧化应激和炎症。
GC10991 SGS 518 oxalate SGS 518 oxalate 是一种选择性 5-HT6R 拮抗剂。
GC12559 NPY 5RA972 neuropeptide Y Y5 receptor antagonist
GC16171 PF 514273 CB1 receptor antagonist
GC13265 Donitriptan hydrochloride 5-HT1B/1D receptors agonist, potent and selective
GC10937 FR 171113 FR171113 是一种特异性的非肽类凝血酶受体拮抗剂。
GC15990 VU 0238429
HY-12157, ML129
A muscarinic M₅ receptor positive allosteric modulator
GC16567 CYM 5442 hydrochloride
邻甲苯磺酰胺
A selective SIP₁ receptor agonist
GC15268 Org 12962 hydrochloride
Ro 44-6956
A 5-HT_2C receptor agonist
GC17413 (±)-5'-Chloro-5'-deoxy-ENBA adenosine A1 receptor agonist, selective and high-affinity
GC12245 SB 612111 hydrochloride
(5R,7R)-REL-7-[[4-(2,6-二氯苯基)-1-哌啶基]甲基]-6,7,8,9-四氢-1-甲基-5H-苯并环庚烯-5-醇盐酸盐
SB 612111 hydrochloride 是一种新型有效的人类鸦片受体样孤儿受体 (ORL-1) 拮抗剂，对 hORL-1 具有高亲和力 (Ki=0.33 nM)。
GC17253 SB 657510
2-溴-N-[4-氯-3-[[(3R)-1-甲基-3-吡咯烷基]氧基]苯基]-4,5-二甲氧基-苯磺酰胺
SB 657510 是一种选择性尿紧张素 II (UII) 受体 (UT) 拮抗剂。
GC17147 LU AA33810 An antagonist of NPY receptor Y₅
GC11787 ML 10302 hydrochloride ML 10302 hydrochloride 是一种有效的选择性 5-HT4 受体激动剂，EC50 为 4 nM。
GC12441 S 25585
S 25585 是一种有效的选择性神经肽 Y (NPY) Y5 受体拮抗剂。
GC10549 TCS OX2 29 A selective orexin receptor 2 antagonist
GC10994 ATC 0065
MCH1 antagonist,potent and selective
GC13294 PSN 375963 hydrochloride A selective agonist of GPR119
GC16639 NS 304
赛乐西帕,NS-304; ACT-293987
An IP receptor agonist prodrug
GC14738 LY 393558 A serotonin reuptake inhibitor
GC17846 SNAP 94847 hydrochloride An antagonist of MCH₁
GC10700 ATC 0175 hydrochloride ATC 0175 hydrochloride 是一种有效的、选择性的、具有口服活性的黑色素浓缩激素 1 受体拮抗剂，对 MCH1R、MCH2R 的 IC50 分别为 13.5、>10000 nM。
GC14290 SLV 320
(1R,4R)-4-(2-苯基-7H-吡咯并[2,3-D]嘧啶-4-氨基)环己醇,SLV 320
An adenosine A1 receptor antagonist
GC10304 L-798,106
CM9; GW671021
A selective EP₃ receptor antagonist
GC15092 BGC 20-761 BGC 20-761 是一种选择性 5-HT6 和多巴胺受体拮抗剂（人受体 Ki 值：5-HT6 (20 nM)、5-HT2A (69 nM)、D2 (140 nM)）。
GC13150 SSR 146977 hydrochloride
N'-[1-[3-[(3R)-1-苯甲酰基-3-(3,4-二氯苯基)-3-哌啶基]丙基]-4-苯基-4-哌啶基]-N,N-二甲基脲
NK3 receptor antagonist