Metabolism(代谢)
- PPAR(215)
- 5-alpha Reductase(11)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(10)
- Aminopeptidase(15)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(55)
- CETP(9)
- Cholesterol absorption(1)
- CPT1(2)
- CYP3A/CYP450(18)
- Dehydrogenase(39)
- DHFR(7)
- DGAT(7)
- Dopamine β-hydroxylase(10)
- Enolase(5)
- FAAH(36)
- Factor Xa(59)
- Ferroptosis(193)
- Folate Analogue(2)
- Glucokinase(17)
- HMG-CoA Reductase(37)
- HSP(97)
- IDO(45)
- KRAS-PDEδ(3)
- MAO(6)
- Metabolic Enzymes(6)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(25)
- P450(441)
- PDE(242)
- Phospholipase(129)
- Procollagen C Proteinase(1)
- Saccharometabolism(1)
- SCD(19)
- SGLT(29)
- TPH(4)
- Transferase(26)
- ALP(1)
- Carbohydrates(33)
- Transaminase(3)
- Glutathione Reductase(1)
- Catalase(11)
- monooxygenase(1)
- PKM2(1)
- Aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(17)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(101)
- Pyruvate kinase(13)
- Others(64)
- MGL(1)
- Galactosidase(2)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(8)
- Dihydroorotate Dehydrogenase(13)
- Bile Acids & Microbiome(119)
- Bone Growth & Remodeling(53)
- Carbohydrate Metabolism(161)
- Cofactors & Vitamins(84)
- Dyslipidemias(103)
- Inborn Errors of Metabolism(97)
- Metabolic Syndrome(22)
- Necroptosis(11)
- Necrosis(16)
- Nutrient Sensing(14)
- Phosphodiesterase(33)
- Reproductive Biology(172)
- Thermogenesis(8)
- Sterol Biosynthesis(40)
- Prolyl Hydroxylation Enzymes(2)
- Biliary System(11)
- Metabolic Disease(5)
- Fat Mass and Obesity-associated Protein (FTO)(5)
- SHIP(1)
- Furin(1)
- Liposome(8)
- PI5P4K(1)
- Metabolic Diseases(2)
- Cat.No. 产品名称 Information
-
GC40365
(±)8(9)-EpETE
(±)8,9-EEQ, (±)8,9-epoxy Eicosatetraenoic Acid
Epoxygenase metabolite of EPA -
GC40363
(±)5(6)-DiHETE lactone
A lactone form of (±)5(6)-DiHETE
-
GC40360
(±)14(15)-EpETE
(±)14,15 EEQ, (±)14,15epoxy Eicosatetraenoic Acid
An EPA congener of (±)14(15)-EpETrE with EDHF activity -
GC40341
Tetrahydro-11-deoxy Cortisol
四氢化-11-脱氧皮质醇
A metabolite of 11-deoxycortisol -
GC40338
9-deoxy-9-methylene Prostaglandin E2
9deoxy9methylene PGE2
A stable, isosteric analog of PGE2 -
GC40334
Myristoleic Acid methyl ester
肉豆蔻脑酸甲酯
Methyl ester of the cytotoxin myristoleic acid -
GC40328
1,7-Dimethyluric Acid
1,7-二甲基尿酸
A caffeine metabolite -
GC40319
10-PAHSA
A FAHFA with anti-diabetic potential
-
GC40301
Tamoxifen N-oxide
他莫昔芬N-氧化物
A metabolite of tamoxifen -
GC40299
L-(+)-Erythrose
L-赤藓糖
An aldotetrose carbohydrate -
GC40298
N-acetyl-5-Aminosalicylic Acid
5-乙酰氨基水杨酸
A metabolite of 5-ASA and sulfasalazine -
GC40286
(E,Z)-2-propyl-2-Pentenoic Acid
2-丙基-2-戊烯酸
A valproic acid metabolite -
GC40282
(+)-5-trans Cloprostenol
5,6-反式-氯前列醇
Less active isomer of (+)-Cloprostenol -
GC40279
(±)11(12)-DiHET
(±)11,12DiHETrE
An epoxide metabolite and potent vasodilator -
GC40272
(±)8(9)-DiHET
(±)8,9DiHETrE
A CYP450 metabolite of arachidonic acid -
GC40268
(±)14(15)-DiHET
(±)14,15DiHETrE
A urinary metabolite of (±)14(15)-EET -
GC19536
6'-Sialyllactose Sodium Salt
6'-唾液乳糖钠盐,6'-N-Acetylneuraminyl-D-lactose
A major milk oligosaccharide -
GC34939
UAMC-3203 hydrochloride
A ferroptosis inhibitor
-
GC34895
D159687
D159687是一种选择性PDE4D抑制剂。
-
GC34705
PDE2/PDE10-IN-1
PDE2/PDE10-IN-1是一种磷酸二酯酶PDE2和PDE10抑制剂,IC50分别为29和480nM。
-
GC34634
JG-98
3-苄基-2-((Z)-((E)-5-(6-氯-3-甲基苯并[D]噻唑-2(3H)-亚基)-3-乙基-4-氧代噻唑啉-2-亚基)甲基)噻唑-3-鎓氯化物
JG-98 is an allosteric inhibitor of Hsp70 that binds tightly to a deep pocket that is conserved in members of the Hsp70 family. JG-98 induces classical apoptosis features, including morphological changes consistent with programmed cell death and positive annexin staining. JG-98 exhibits anticancer activity. -
GC34623
IACS-8968 S-enantiomer
IACS-8968(S-enantiomer)是IACS-8968的S型对映异构体。IACS-8968是IDO和TDO的双抑制剂,其pIC50s值分别为6.43,<5。
-
GC34622
IACS-8968 R-enantiomer
IACS-8968(R-enantiomer)是IACS-8968的R型对映异构体。IACS-8968是IDO和TDO的双抑制剂,其pIC50s值分别为6.43,<5。
-
GC34621
IACS-8968
IACS-8968是IDO和TDO的双抑制剂,其pIC50s值分别为6.43,<5。
-
GC34613
HFI-142
HFI-142是胰岛素调节性氨基肽酶(IRAP)抑制剂,ki值为2.01μM。
-
GC34562
DT-061
DT-061 (SMAP) is a bioavailable PP2A activator. It decreases cell viability in HCC827 and HCC3255 cell lines, with IC50 values of 14.3 μM and 12.4 μM respectively.
-
GC34539
Col003
Col003是一种有效的Hsp47抑制剂,竞争性地与Hsp47上的胶原结蛋白合位点结合(IC50,1.8μM),通过破坏胶原蛋白的三重螺旋结构抑制胶原蛋白的分泌。
-
GC19512
Bay 60-7550
BAY 607550
A potent and selective PDE2 inhibitor -
GC19508
BLU-782
Activin Receptor-like Kinase 2 Inhibitor 1, ALK2-IN-1, Fidrisertib
BLU-782 是一种口服精准疗法,专门设计用于选择性靶向突变体 ALK2。 -
GC19504
LJ570
LJ570 是一种 PPARα/PPARγ 双重激动剂,EC50 分别为 1.05 和 0.12 μM。
-
GC11870
4-Methylumbelliferyl-β-D-Glucopyranoside
4-甲基伞形酮酰-Β-D-吡喃葡糖酸苷,4-MU-GLU;4-MU-β-Gluc;4-MUG;MU-GLU
A fluorescent substrate of β-glucosidase and β-glucocerebrosidase -
GC40258
Tetrahydropiperine
四氢胡椒碱
A derivative of piperine -
GC40236
1,2-Dilinoleoyl-sn-glycerol
1,2-Dioleoyl-sn-glycerol
A DAG -
GC40233
Vitamin D3-d7
维生素D3 D7
Vitamin D3-d7 is intended for use as an internal standard for the quantification of vitamin D3 by GC- or LC-MS. -
GC40231
Milrinone-d3
An internal standard for the quantification of milrinone
-
GC40228
Fluvastatin-d6 (sodium salt)
An internal standard for the quantification of fluvastatin
-
GC40226
Curcumin-d6
(1E,4Z,6E)-5-羟基-1,7-二[4-羟基-3-(甲氧基-D3)苯基]-1,4,6-庚三烯-3-酮,Diferuloylmethane-d6; Natural Yellow 3-d6; Turmeric yellow-d6
An internal standard for the quantification of curcumin -
GC40220
Pravastatin-d3 (sodium salt)
An internal standard for the quantification of pravastatin
-
GC40211
Ferrostatin-1 Diyne
A ferroptosis inhibitor
-
GC40203
Cholesterol-d6
胆固醇-26,26,26,27,27,27-D6
An internal standard for the quantification of cholesterol -
GC40201
7β-hydroxy Cholesterol-d7
7BETA-羟基胆固醇-25,26,26,26-27,27,27-D7
An internal standard for the quantification of 7β-hydroxy cholesterol -
GC40193
UAMC-3203
A ferroptosis inhibitor
-
GC40191
Ibuprofen Carboxylic Acid
羧基布洛芬
A major metabolite of ibuprofen -
GC40190
Febuxostat Acyl Glucuronide
非布司他杂质
A metabolite of febuxostat -
GC40167
1,3-Dipalmitoyl-2-Docosahexaenoyl-rac-glycerol
1,3-Palmitin-2-Docoahexaenoin, 16:0/22:6/16:0-TG, TG(16:0/22:6/16:0)
A triacylglycerol -
GC40145
(S)-Laudanosine
(+)-Laudanosine, L-Laudanosine, L-(+)-Laudanosine, NSC 35045
The (S) enantiomer of laudanosine -
GC40144
Levofloxacin N-oxide
左氧氟沙星EP杂质C (Levofloxacin N-Oxide)
An inactive metabolite of levofloxacin -
GC40143
Dihydrotetrabenazine
反式(2,3)-二氢丁苯那嗪
An active metabolite of tetrabenazine -
GC40142
Lactosylceramides (bovine buttermilk)
乳糖苷
A sphingolipid -
GC40132
ACTH (6-24) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
HFRWGKPVGKKRRPVKVYP
A peptide fragment of ACTH