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Monoamine oxidases (MAOs) are a family of enzymes that oxidize a number of biogenic amines through the production of hydrogen peroxide (H2O2). Two members of the MAO family have been identified and designated, MAO A and MAO B, which are encoded by two homologous genes comprising 15 exons with identical intro-exon organization and exhibit substrate-specificity. MAO A displays higher affinity towards serotonin, norepinephrine and dopamine; while MAO B displays higher affinity towards phenylethylamine and benzylamine.  Four highly conserved regions associated with the catalytic activity of mammalian MAO enzymes have been identified, including an ADP binding β-α-β unit, a putative substrate-binding domain, a FAD covalent attachment site, and a C terminus region predicted to form a transmembrane-associated α-helix.

Products for  MAO

  1. Cat.No. 产品名称 Information
  2. GC14122 Clorgyline (hydrochloride)


    A selective, irreversible monoamine oxidase A inhibitor
  3. GC16824 Pargyline (hydrochloride)


    An irreversible MAO inhibitor
  4. GC12962 Isatin


    Isatin (Indoline-2,3-dione) 是一种有效的单胺氧化酶 (MAO) 抑制剂,IC50 为 3 μM。
  5. GC11703 Moclobemide (Ro 111163)

    吗氯贝胺; Ro111163

    An Analytical Reference Standard
  6. GC14673 Safinamide Mesylate

    沙芬酰胺甲磺酸盐,FCE-28073, PNU 151774E, methanesulfonate

    An inhibitor of MAO-B
  7. GC12801 Rasagiline Mesylate

    甲磺酸雷沙吉兰; (R)-AGN1135 mesylate; TVP1012 mesylate

    An inhibitor of MAO-B

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