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5-alpha Reductase(5-α还原酶)

5-alpha-reductase is an enzyme steroid that catalyzes the conversion of testosterone into the more potent androgen dihydrotestosterone. It plays an important role in male developmental biology, physiology and pharmacology.

  1. Cat.No. 产品名称 Information
  2. GC64008 12-O-Methylcarnosic acid 12-O-Methylcarnosic acid 是一种从小叶鼠尾草的丙酮提取物中分离出来的二萜鼠尾草酸,是抑制 5α-还原酶的活性成分,IC50 值为 61.7 μM。12-O-Methylcarnosic acid 具有抗氧化活性,对预防胃部病变。12-O-Methylcarnosic acid 可以通过下调 HMV-II 黑色素瘤细胞中酪氨酸酶的表达来抑制黑色素的产生。12-O-Methylcarnosic acid 可能具有抗糖尿病活性,它能够显着激活过氧化物酶体增殖物激活受体 (PPAR)γ .
  3. GC50279 MK 386 Potent, selective human type 1 5α-reductase inhibitor
  4. GC37691 Stigmasterol glucoside
  5. GC32953 Epristeride (ONO-9302)
  6. GC32422 CGP-53153
  7. GC15975 α-Estradiol A weak estrogen with neuroprotective effects
  8. GC17572 Finasteride acetate An inhibitor of 5α-reductase type II
  9. GC10893 Dutasteride An inhibitor of steroid 5α-reductase
  10. GC16248 Finasteride An inhibitor of 5α-reductase type II

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