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Home >> Signaling Pathways >> Metabolism >> PDE

PDE(磷酸二酯酶)

PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.

  1. Cat.No. 产品名称 Information
  2. GC25001 (R)-Avanafil R-Avanafil is a strong competitive inhibitor of phosphodiesterase 5 (PDE5) with a demonstrated in vitro IC 50 of 5.2 nM.
  3. GC67967 Dovramilast
  4. GC67864 (R)-Irsenontrine
  5. GC66042 Enpp-1-IN-14
  6. GC65925 TDP1 Inhibitor-1
  7. GC65911 Irsenontrine
  8. GC65426 CM-675
  9. GC65360 PDE10-IN-5
  10. GC65302 SDZ-MKS 492
  11. GC65258 PDE10A-IN-2 hydrochloride
  12. GC65246 Deltasonamide 2
  13. GC65173 FCPR03
  14. GC65081 CALP1 TFA
  15. GC65039 PDE11-IN-1
  16. GC65002 PF-05085727
  17. GC64973 ATX inhibitor 1
  18. GC64931 ONO-8430506
  19. GC64844 NPD-001
  20. GC64773 Orismilast
  21. GC64703 BAY 2666605 BAY 2666605 is an orally active phosphodiesterase 3A (PDE3A) and phosphodiesterase 3B (PDE3B) inhibitor with IC50s of 87 nM and 50 nM, respectively.
  22. GC64675 TMX-4113
  23. GC64522 Roflupram
  24. GC64012 Hcyb1
  25. GC64005 FPFT-2216
  26. GC63997 S32826 disodium Inhibitor of autotaxin (lysophospholipase D)
  27. GC63701 Senazodan hydrochloride
  28. GC63520 TMX-4100
  29. GC63505 PDE12-IN-1
  30. GC63308 N-Desmethyl Sildenafil-d8
  31. GC63209 TAK-915
  32. GC62977 FR-229934
  33. GC62589 Difamilast
  34. GC62525 LEO 39652
  35. GC62466 Ensifentrine
  36. GC62409 Tovinontrine
  37. GC62403 ATX inhibitor 5
  38. GC62234 DNMDP
  39. GC61943 Thioquinapiperifil dihydrochloride
  40. GC61747 Sp-cAMPS
  41. GC61508 CALP2 TFA
  42. GC47939 PF-04449613 A PDE9A inhibitor
  43. GC60329 Robustine
  44. GC60199 Ilexsaponin B2
  45. GC60074 BI-2545 An inhibitor of autotaxin
  46. GC60063 Ayanin
  47. GC60024 3-O-Methylquercetin A flavone with diverse biological activities
  48. GC39539 Moracin M
  49. GC39453 THPP-1 A PDE10A inhibitor
  50. GC39415 OR-1896
  51. GC50419 A 33 A 33 是一种具有口服活性的选择性 PDE4B 抑制剂，IC50 为 15 nM。

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