PDE(磷酸二酯酶)
PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.
- Cat.No. 产品名称 Information
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GC25001
(R)-Avanafil
R-Avanafil is a strong competitive inhibitor of phosphodiesterase 5 (PDE5) with a demonstrated in vitro IC 50 of 5.2 nM.
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GC67967
Dovramilast
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GC67864
(R)-Irsenontrine
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GC66042
Enpp-1-IN-14
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GC65925
TDP1 Inhibitor-1
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GC65911
Irsenontrine
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GC65426
CM-675
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GC65360
PDE10-IN-5
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GC65302
SDZ-MKS 492
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GC65258
PDE10A-IN-2 hydrochloride
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GC65246
Deltasonamide 2
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GC65173
FCPR03
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GC65081
CALP1 TFA
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GC65039
PDE11-IN-1
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GC65002
PF-05085727
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GC64973
ATX inhibitor 1
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GC64931
ONO-8430506
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GC64844
NPD-001
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GC64773
Orismilast
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GC64703
BAY 2666605
BAY 2666605 is an orally active phosphodiesterase 3A (PDE3A) and phosphodiesterase 3B (PDE3B) inhibitor with IC50s of 87 nM and 50 nM, respectively.
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GC64675
TMX-4113
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GC64522
Roflupram
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GC64012
Hcyb1
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GC64005
FPFT-2216
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GC63997
S32826 disodium
Inhibitor of autotaxin (lysophospholipase D)
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GC63701
Senazodan hydrochloride
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GC63520
TMX-4100
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GC63505
PDE12-IN-1
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GC63308
N-Desmethyl Sildenafil-d8
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GC63209
TAK-915
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GC62977
FR-229934
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GC62589
Difamilast
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GC62525
LEO 39652
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GC62466
Ensifentrine
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GC62409
Tovinontrine
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GC62403
ATX inhibitor 5
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GC62234
DNMDP
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GC61943
Thioquinapiperifil dihydrochloride
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GC61747
Sp-cAMPS
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GC61508
CALP2 TFA
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GC47939
PF-04449613
A PDE9A inhibitor
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GC60329
Robustine
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GC60199
Ilexsaponin B2
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GC60074
BI-2545
An inhibitor of autotaxin
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GC60063
Ayanin
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GC60024
3-O-Methylquercetin
A flavone with diverse biological activities
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GC39539
Moracin M
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GC39453
THPP-1
A PDE10A inhibitor
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GC39415
OR-1896
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GC50419
A 33
A 33 是一种具有口服活性的选择性 PDE4B 抑制剂,IC50 为 15 nM。