Ferroptosis(铁死亡)

Ferroptosis is a unique iron-dependent form of nonapoptotic cell death. It is triggered by oncogenic RAS-selective lethal small molecule erastin. Acitvation of ferroptosis lead to nonapoptotic destruction of cancer cells.

Cat.No. 产品名称 Information
GC52467 Cell Death Screening Library For screening a variety of cell death pathways
GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid
GC52317 BCP-T.A. A ferroptosis inducer
GC52290 (R)-HTS-3 An inhibitor of LPCAT3
GC52190 Imidazole Ketone Erastin A ferroptosis inducer
GC52164 Cu-ATSP A copper-containing bis(thiosemicarbazone) complex
GC65163 Ardisiacrispin B
GC65095 L-Glutamic acid-d5
GC65068 L-Glutamine 15N
GC49868 D-α-Tocopheryl Quinone An oxidative metabolite of vitamin E
GC64352 L-Glutamic acid-15N
GC49730 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 An internal standard for the quantification of 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE
GC49697 GPX4 Inhibitor 26a A GPX4 inhibitor
GC49691 PSP A two-photon fluorescent probe for H₂S_n
GC49560 L6H21 An inhibitor of the MD-2 and TLR4 interaction
GC49454 Complex 3 A fluorescent copper complex with anticancer activity
GC49308 Ungeremine A betaine-type alkaloid with diverse biological activities
GC49058 DTPA A cell-impermeable metal chelating agent
GC49034 1(R)-(Trifluoromethyl)oleyl alcohol An oleic acid analog
GC62643 L-Buthionine-(S,R)-sulfoximine hydrochloride An irreversible inhibitor of the γ-glutamylcysteine synthetase
GC61895 Ammonium iron(III) citrate Ammonium ferric citrate (Ferric ammonium citrate, Ammonium iron(III) citrate, Iron ammonium citrate, FerriSeltz) induces ferroptosis in non-small-cell lung carcinoma through the inhibition of GPX4-GSS/GSR-GGT axis activity.
GC61436 Gallic acid hydrate A phenol with diverse biological activities
GC48954 CP21 An iron chelator
GC48650 DTUN A lipophilic hyponitrite radical initiator
GC48059 Rosiglitazone-d3 An internal standard for the quantification of rosiglitazone
GC48030 RC574
An inhibitor of ferroptosis
GC48029 RC363 An inhibitor of ferroptosis
GC47870 Pantothenate Kinase Inhibitor A reversible inhibitor of pantothenate kinase
GC47478 JKE-1716 A GPX4 inhibitor
GC47477 JKE-1674 A GPX4 inhibitor and active metabolite of ML-210
GC47123 Coumarin-Quinone Conjugate A fluorescent substrate for NADH:ubiquinone oxidoreductases
GC47065 CAY10773 A derivative of sorafenib
GC46352 (S)-DO271 An inactive control for DO264
GC61187 Pioglitazone D4 An internal standard for the quantification of pioglitazone
GC50345 Liproxstatin-1 hydrochloride A ferroptosis inhibitor
GC45995 DO264 An ABHD12 inhibitor
GC45928 iFSP1 An inhibitor of AIFM2/FSP1
GC45793 IM-93 A dual inhibitor of ferroptosis and NETosis
GC45792 Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) An inducer of ferroptosis
GC38429 Dihydroartemisinic acid A precursor to artemisinin
GC37665 Sorafenib (D4)
GC37664 Sorafenib (D3) An internal standard for the quantification of sorafenib
GC36926 Piperazine Erastin A ferroptosis inducer
GC36011 Ethylenediaminetetraacetic acid trisodium salt Ethylenediaminetetraacetic acid (EDTA) is a chelating agent commonly used in protein purification, both to eliminate contaminating divalent cations and to inhibit protease activity.
GC35876 DL-Glutamine DL-Glutamine (Glutamin, 2-amino-4-carbamoylbutanoic acid) is a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes.
GC35795 D,L-Buthionine-(S,R)-sulfoximine hydrochloride A γ-glutamylcysteine synthetase inhibitor
GC35692 Chrysosplenetin A flavonoid with diverse biological activities
GC35399 Artefenomel An antimalarial agent
GC35398 Arteannuin B A precursor to artemisinin with diverse biological activities
GC34980 (E)-Ferulic acid Trans-ferulic acid is a potent activator of AMPKunder high glucose condition.