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Home >> Signaling Pathways >> Metabolism >> Ferroptosis

Ferroptosis(铁死亡)

Ferroptosis is a unique iron-dependent form of nonapoptotic cell death. It is triggered by oncogenic RAS-selective lethal small molecule erastin. Acitvation of ferroptosis lead to nonapoptotic destruction of cancer cells.

Products for  Ferroptosis

  1. Cat.No. 产品名称 Information
  2. GC35398 Arteannuin B A precursor to artemisinin with diverse biological activities
  3. GC34980 (E)-Ferulic acid Trans-ferulic acid is a potent activator of AMPKunder high glucose condition.
  4. GC45248 (-)-FINO2 A ferroptosis inducer
  5. GC44947 SRS16-86 A ferroptosis inhibitor
  6. GC44893 Siramesine (fumarate) A selective σ2 receptor agonist
  7. GC44851 Rosiglitazone (potassium salt) A PPARγ agonist
  8. GC44214 ML-162 A GPX4 inhibitor
  9. GC43623 Erastin2 Erastin2 is a potent system xc- inhibitor and ferroptosis-inducing agent [1].
  10. GC43329 Cu-ATSM A copper-containing compound with diverse biological activities
  11. GC43297 Coenzyme Q2 A biosynthetic precursor to CoQ10 and an inhibitor of mitochondrial complex I
  12. GC43231 Cerivastatin (sodium salt) An inhibitor of HMG-CoA reductase
  13. GC42928 BHT A synthetic antioxidant
  14. GC42042 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE

    An oxidized phospholipid
  15. GC42041 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC

    An oxidized phospholipid
  16. GC42040 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE

    An oxidized phospholipid
  17. GC42039 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC An oxidized phospholipid
  18. GC41293 Glutathione ethyl ester A cell-permeable derivative of glutathione
  19. GC40922 SRS11-92 A ferroptosis inhibitor
  20. GC34939 UAMC-3203 hydrochloride A ferroptosis inhibitor
  21. GC40226 Curcumin-d6 An internal standard for the quantification of curcumin
  22. GC40211 Ferrostatin-1 Diyne A ferroptosis inhibitor
  23. GC40193 UAMC-3203 A ferroptosis inhibitor
  24. GC34070 Brusatol (NSC 172924) A quassinoid with diverse biological activities
  25. GC34058 NADPH tetrasodium salt A reduced form of NADP+
  26. GC34057 TBHQ (tert-Butylhydroquinone) Tert-butylhydroquinone (TBHQ) is an antioxidant compound which is used to prevent lipid peroxidation and shows multiple cytoprotective actions. It is an activator of Nrf2.
  27. GC33469 NADPH tetracyclohexanamine A reduced form of NADP+
  28. GC33098 L-Buthionine-(S,R)-sulfoximine (L-Butionine sulfoximine)

    An irreversible inhibitor of the γ-glutamylcysteine synthetase
  29. GC33023 D,L-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) A γ-glutamylcysteine synthetase inhibitor
  30. GC32723 CDDO-Im (RTA-403) An activator of Nrf2 signaling
  31. GC32237 CIL56 An inducer of non-apoptotic cell death
  32. GC31940 Docebenone (AA 861) A 5-LO inhibitor
  33. GC31492 Vildagliptin dihydrate (LAF237 dihydrate) A DPP-4 inhibitor
  34. GC30788 L-Glutamic acid monosodium salt (Monosodium glutamate) L-Glutamic acid monosodium salt is the sodium salt of glutamic acid, found naturally in tomatoes, cheese and other foods. L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
  35. GC30512 Vatiquinone (EPI-743) A metabolite of α-tocotrienol with antioxidant and ferroptosis inhibitory activity
  36. GC30067 Butylhydroxyanisole (Butylated hydroxyanisole) 丁基羟基茴香醚（Butylated hydroxyanisole）（Butylated hydroxyanisole）是一种抗氧化剂，用作食品添加剂防腐剂。
  37. GC30039 FIN56

    FIN56, a novel ferroptosis inducer, triggers ferroptosis by increasing the degradation of GPX4 .
  38. GC19457 Trolox

    Vitamin E derivative with antioxidant properties
  39. GC19254 ML385

    An inhibitor of Nrf2
  40. GC18705 ML-210 A GPX4 inhibitor
  41. GC10331 Ebselen A peroxynitrite scavenger
  42. GC14591 Hemin chloride An oxidized form of heme
  43. GC16517 Eugenol 丁香酚是一种存在于丁香中的精油，具有抗菌、驱虫和抗氧化活性。
  44. GC10042 Vitamin E 脂溶性维生素
  45. GC12431 RSL3

    谷胱甘肽过氧化物酶4抑制剂
  46. GC13554 Deferoxamine mesylate An iron chelator and inhibitor of prolyl hydroxylases
  47. GC15399 Dp44mT An iron chelator with antiproliferative effects
  48. GC15681 Liproxstatin-1

    A ferroptosis inhibitor
  49. GC11882 GKT137831 A dual NOX1/NOX4 inhibitor
  50. GC12205 PD 146176 Inhibitor of reticulocyte 15-lipoxygenase-1
  51. GC12203 L-Glutathione Reduced

    Nucleophilic co-substrate to glutathione transferases and electron donor to glutathione peroxidases

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