Dehydrogenase(脱氢酶)
Dehydrogenases, belonging to the class of oxidoreductases which catalyze donor-acceptor reactions to transfer electron molecules from the oxidant to the reluctant, are a diverse group of enzymes that are able to transfer one or more hydrides (H-) from a substrate to an electron acceptor, such as nicotinamide adenine dinucleotide (NAD+), nicotinamide adenine dinucleotide phosphate (NADP+) or Riboflavin, through oxidation and reduction. Three commonly studied dehydrogenase enzymes include alcohol dehydrogenase (ADH) which catalyzes the reduction of acetylaldehyde to ethanol in plant cells, succinate dehydrogenase which oxidizes succinate to fumarate, and lactate dehydrogenase which catalyzes the reversible oxidation of lactate to pyruvate.
- Cat.No. 产品名称 Information
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GP26172
PGD Human, Active
PGD Human Recombinant produced in E
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GP26169
NQO1 Human, Active
NQO1 Human Recombinant produced in E
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GP26164
LDHA, E.Coli Active
LDHA E
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GC25389
Ethyl potassium malonate
Ethyl potassium malonate (Potassium 3-ethoxy-3-oxopropanoate) is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate.
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GC25039
AG-120 (racemic)
AG-120 (racemic), the racemic mixture of AG-120, is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity.
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GC50509
PKUMDL WQ 2201
Negative allosteric modulator of 3-Phosphoglycerate dehydrogenase (PHGDH)
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GC50508
PKUMDL WQ 2101
Negative allosteric modulator of 3-phosphoglycerate dehydrogenase (PHGDH)
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GC16860
NCT-502
A PHGDH inhibitor
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GC13262
A-771726
An active metabolite of leflunomide
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GC17293
PHGDH-inactive
A negative control for NCT-502 and NCT-503
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GC15547
Inosine-5'-monophosphate (sodium salt hydrate)
A 5’-ribonucleoside
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GC10462
6-Aminonicotinamide
Inhibitor of 6-phosphogluconate dehydrogenase
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GC15943
NCT-503
A PHGDH inhibitor
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GC13776
Piericidin A
A potent inhibitor of mitochondrial complex I
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GC12204
STK393606
A selective inhibitor of 15-PGDH
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GC14415
ML390
A DHODH inhibitor
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GC15601
AG-120
An IDH1 inhibitor
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GC13147
AG-221 (Enasidenib)
An inhibitor of mutant IDH2
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GC17914
Fomepizole
An alcohol dehydrogenase inhibitor
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GC11149
L-a-Hydroxyglutaric acid disodium salt
An α-hydroxy acid
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GC13579
DL-α-Hydroxyglutaric acid disodium salt
An α-hydroxy acid
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GC15738
BVT 2733
An 11β-HSD1 inhibitor
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GC13336
CBR-5884
A selective PHGDH inhibitor
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GC13464
GSK 2837808A
GSK2837808A is a selective inhibitor of lactate dehydrogenase A (LDHA) with IC50 of 2.
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GC10902
CVT 10216
A selective, reversible ALDH2 inhibitor
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GC16951
Stiripentol
An antiepileptic compound
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GC15266
Qc 1
Qc 1 是一种可逆的非竞争性苏氨酸脱氢酶 (TDH) 抑制剂。
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GC13760
TC HSD 21
An inhibitor of 17β-HSD3
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GC16597
Alda 1
A selective ALDH2 agonist
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GC13611
CGP 3466B maleate
A GAPDH ligand
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GC16816
Galloflavin
An inhibitor of lactate dehydrogenase
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GC10438
WIN 18446
An inhibitor of aldehyde dehydrogenase 1a2
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GC13670
Methylmalonate
A dicarboxylic acid and byproduct of propionate catabolism
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GC14851
Vidofludimus
An immunosuppressive drug that inhibits DHODH
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GC14757
AGI-6780
A potent, selective inhibitor of mutant IDH2
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GC17107
PluriSIn #1 (NSC 14613)
A selective inhibitor of stearoyl-CoA desaturase
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GC14783
Trilostane
A 3β-hydroxysteroid dehydrogenase inhibitor
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GC17467
Gimeracil
A DYPD inhibitor
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GC10531
AGI-5198
A potent, selective inhibitor of IDH1 mutations
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GC13614
Mycophenolate Mofetil
A prodrug form of mycophenolic acid
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GC14921
CPI-613
An inhibitor of α-ketoglutarate dehydrogenase