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Home >> Signaling Pathways >> Metabolism >> SGLT

SGLT(钠-葡萄糖协同转运蛋白)

SGLT (sodium-glucose linked transporter) uses the energy from the downhill sodium ion gradient created by the ATPase pump to transport glucose across the apical membrane against an uphill glucose gradient.

  1. Cat.No. 产品名称 Information
  2. GC64266 Enavogliflozin
  3. GC60249 Mizagliflozin Mizagliflozin (KWA 0711) is a novel, potent, selective sodium glucose co-transporter 1 (SGLT1) inhibitor with Ki of 27 nM for human SGLT1. The selectivity ratio (Ki value for human SGLT2/Ki value for human SGLT1) of mizagliflozin is 303. Mizagliflozin shows the potential use for the amelioration of chronic constipation.
  4. GC39178 Canagliflozin D4 An internal standard for the quantification of canagliflozin
  5. GC36498 LX2761
  6. GC36326 Ipragliflozin L-Proline Ipragliflozin L-Proline is an orally active and selective inhibitor of SGLT2 with IC50 of 7.38 nM, 6.73 nM and 5.64 nM for human SGLT2, rat SGLT2 and mouse SGLT2, respectively.
  7. GC36004 Ertugliflozin L-pyroglutamic acid Ertugliflozin (MK-8835, PF-04971729) L-pyroglutamic acid is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2) with IC50 of 0.877 nM for h-SGLT2. Ertugliflozin has the potential for the treatment of type 2 diabetes mellitus.
  8. GC35809 Dapagliflozin ((2S)-1,2-propanediol, hydrate) Dapagliflozin propanediol belongs to the class of orally administered antidiabetic agents designated as sodiumglucose cotransporter 2 (SGLT2) inhibitors.
  9. GC35603 Canagliflozin hemihydrate An inhibitor of SGLT2
  10. GC41374 Trilobatin A dihydrochalcone glucoside with diverse biological activities
  11. GC31593 Velagliflozin
  12. GC31461 Tofogliflozin (CSG452) Tofogliflozin (CSG 452) is a novel sodium-glucose co-transporter 2(SGLT2) inhibitor with IC50 values of 2.9 nM and 8444 nM for hSGLT2 and hSGLT1, respectively.
  13. GC31377 Tofogliflozin hydrate (CSG-452 hydrate) A potent inhibitor of SGLT2
  14. GC31366 Licogliflozin (LIK066)
  15. GC19065 Bexagliflozin A SGLT2 inhibitor
  16. GC17190 galacto-Dapagliflozin A potent inhibitor of hSGLT2
  17. GC16697 fluoro-Dapagliflozin A potent inhibitor of hSGLT2
  18. GC16469 Ipragliflozin An SGLT2 inhibitor
  19. GC13771 Canagliflozin An inhibitor of SGLT2
  20. GC15530 Dapagliflozin An SGLT2 inhibitor
  21. GC16212 Empagliflozin (BI 10773) An SGLT2 inhibitor
  22. GC17976 Phloretin A natural inhibitor of various transporters
  23. GC16012 PF-04971729 An SGLT2 inhibitor
  24. GC15088 LX-4211 An SGLT inhibitor
  25. GN10029 Phloridzin An inhibitor of sodium-glucose cotransporters

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