Factor Xa(凝血因子 Xa)
Factor Xa is a trypsin-like serine protease that catalyzes the cleavage of peptide bonds on the carboxyl side (P’1) of a basic amino acid residue with a preference to cleave peptide bonds of carboxyl function provided by an argininyl residue. Factor Xa plays an essential role in the coagulation cascade catalyzing the conversion of prothrombin to thrombin on surface of vascular cells to link the extrinsic and intrinsic pathways, in which it forms the Ca2+- and phospholipid-dependent prothrombinase complex with cofactor V/Va on activated platelets, monocytes or endothelial cells. Moreover, factor Xa has been found to mediate the stimulation of lymphocyte proliferation, induce the mitogenesis of endothelial and smooth muscle cells, and trigger acute inflammatory responses in vivo.
- Cat.No. 产品名称 Information
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GC25137
Betrixaban maleate
Betrixaban maleate is the maleate salt form of Betrixaban, which is a Factor Xa inhibitor that decreases prothrombinase activity and thrombin generation.
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GC65912
Asundexian
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GC65060
Fitusiran
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GC63873
Milvexian
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GC49684
Dabigatran-13C-d3
An internal standard for the quantification of dabigatran
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GC49682
Dabigatran-d3
An internal standard for the quantification of dabigatran
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GC49614
Acenocoumarol-d4
Acenocoumarol-d4 是氘标记的 Acenocoumarol。
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GC49518
Fluindione
A vitamin K antagonist
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GC62922
Darexaban
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GC49322
GGACK (hydrochloride)
A uPA and factor Xa inhibitor
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GC49131
Dehydro Warfarin
A metabolite of (±)-warfarin
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GC49118
10-hydroxy Warfarin
A metabolite of (R)-warfarin
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GC62439
Edoxaban impurity 6
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GC62298
Edoxaban impurity 4
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GC19766
Heparin sodium salt (MW 15kDa)
肝素钠盐(MW 15kDa)(Sodium heparin (MW 15kDa))是肝素的聚合物,分子量为15kDa。
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GC61748
Betrixaban D6
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GC47280
Edoxaban-d6
An internal standard for the quantification of edoxaban
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GC46879
Argatroban-d3 (hydrochloride)
An internal standard for the quantification of argatroban
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GC46863
Apixaban-13C-d3
An internal standard for the quantification of apixaban
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GC60326
Rivaroxaban D4
An internal standard for the quantification of rivaroxaban
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GC36831
Ozagrel sodium
A selective inhibitor of TXA synthase
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GC36092
FXIa-IN-1
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GC35962
Edoxaban tosylate
A potent inhibitor of Factor Xa
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GC35536
BMS-962212
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GC44966
Sucrose octasulfate (potassium salt)
An alkaline aluminum?sucrose complex
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GC43696
Fondaparinux (sodium salt)
An inhibitor of Factor Xa
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GC32614
BMS-654457
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GC32567
RWJ-445167 (3DP-10017)
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GC17799
Betrixaban
A Factor Xa inhibitor
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GC17726
Otamixaban
Otamixaban(FXV673) 是一种有效的 (Ki = 0.5 nM)、选择性、快速作用、竞争性和可逆的 fXa 抑制剂,可有效抑制游离和凝血酶原结合的 fXa。
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GC12839
Edoxaban tosylate monohydrate
A potent inhibitor of Factor Xa
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GC11644
Edoxaban
Edoxaban (DU-176b) 是一种具有口服活性、高效、选择性和直接的因子 Xa (FXa) 抑制剂,对游离人 FXa 和凝血酶原酶的 Ki 值分别为 0.561 和 2.98 nM。
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GC11101
5-R-Rivaroxaban
5-R-Rivaroxaban 是 Rivaroxaban 的 (R)-对映异构体。
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GC15757
Ozagrel
A selective inhibitor of TXA synthase
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GC13130
Apixaban
An inhibitor of Factor Xa
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GC13683
Rivaroxaban
A selective inhibitor of Factor Xa
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GC13711
Gabexate mesylate
A serine protease inhibitor