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Home >> Signaling Pathways >> Metabolism

Metabolism(代谢)

Cat.No. 产品名称 Information
GC14246 Muraglitazar
莫格他唑 ,BMS-298585
A PPARα and PPARγ dual agonist
GC16824 Pargyline (hydrochloride)
优降宁盐酸盐；盐酸帕吉林；巴吉林盐酸盐
An irreversible MAO inhibitor
GC14591 Hemin chloride
氯化血红素; Hemin chloride
氯化血红素是血红素加氧酶(HO)-1的底物，可诱导多种细胞表达HO-1，发挥抗氧化和抗炎作用。
GC13751 (3S,5S)-Atorvastatin (sodium salt)
阿托伐他汀EP杂质C
An enantiomer of atorvastatin
GC13351 VU0359595
CID-53361951,ML-270
A selective PLD₁ inhibitor
GC11021 Bromoenol lactone
(6E)-Bromoenol lactone
A selective, potent, irreversible inhibitor of iPLA₂
GC12043 CUDA A potent inhibitor of soluble epoxide hydrolase
GC17354 SW203668 An irreversible inhibitor of stearoyl-CoA desaturase
GC16259 SKF 525A (hydrochloride)
盐酸丙基解痉素,RP 5171|U 5446
A nonspecific CYP450 inhibitor
GC15995 BMS 687453 A potent PPARα agonist
GC13776 Piericidin A
粉蝶霉素A,AR 054, Shaoguanmycin B, SN 198E

A potent inhibitor of mitochondrial complex I
GC13763 KT203
ML-296
A potent inhibitor of ABHD6
GC16756 KT182 A potent inhibitor of ABHD6
GC16849 MBCQ An inhibitor of PDE5
GC12204 STK393606 A selective inhibitor of 15-PGDH
GC11155 Omeprazole sulfone
奥美拉唑杂质A,Omeprazole sulfone; Omeprazole sulphone
The major metabolite of omeprazole
GC11916 GQ-16 A PPARγ partial agonist
GC14486 (S)-Mephenytoin
甲秦皮素,(S)-5-Ethyl-3-methyl-5-phenylhydantoin
S-Mephenytoin (5-phenyl-5-ethyl-N-methylhydantoin) 是一种抗惊厥药，通过 N-去甲基化和 4-羟基化（芳环）代谢。
GC12912 BCATc Inhibitor 2
Cytosolic Branched-Chain Amino Acid Transferase Inhibitor 2
A selective BCATc inhibitor
GC10821 11-keto-β-Boswellic Acid
11-酮基-BETA-乳香酸,11-oxo-β-Boswellic acid,KBA
A 5-LO inhibitor
GC10565 7-hydroxycoumarinyl Arachidonate
Umbelliferyl Arachidonate

A substrate for cPLA₂
GC16350 Actinonin
放线酰胺素,(-)-Actinonin,Ro 06-1467
An aminopeptidase inhibitor
GC10430 1-Deoxygalactonojirimycin (hydrochloride)
脱氧半乳糖野生霉素盐酸盐,GR181413A
An α-galactosidase inhibitor and chaperone
GC12595 DL-α-Difluoromethylornithine (hydrochloride hydrate)
依氟鸟氨酸盐酸盐一水合物,DFMO,Eflornithine
An irreversible inhibitor of ornithine decarboxylase
GC10859 Amino Tadalafil
氨基他达拉非
An analog of tadalafil
GC10223 CCT018159 An Hsp90 inhibitor
GC15876 IDO-IN-1
4-氨基-N-(3-溴-4-氟苯基)-N'-羟基-1,2,5-恶二唑-3-甲脒
A potent IDO inhibitor
GC17780 FTase Inhibitor II
Farnesyltransferase Inhibitor II,FTI-II
Ftase inhibitor
GC14282 3-acetyl-11-keto-β-Boswellic Acid
11-羰基-Β-乙酰乳香酸,3-O-acetyl-11-keto-β-Boswellic acid,AKBA
A selective 5-LO inhibitor
GC12493 Desfuroylceftiofur
去呋喃甲酰基头孢噻呋
An active metabolite of ceftiofur
GC10533 7,8-dihydro-L-Biopterin
7,8-二氢生物蝶呤
A precursor in the synthesis of BH₄
GC12624 3,4-DAA A synthetic analog of a tryptophan metabolite
GC15601 AG-120
艾伏尼布,AG-120
An IDH1 inhibitor
GC13147 AG-221 (Enasidenib)
恩西地平; AG-221
An inhibitor of mutant IDH2
GC17003 Benzenesulfonamide
苯磺酰胺
carbonic anhydrase inhibitor
GC12962 Isatin
靛红,Indoline-2,3-dione
Isatin (Indoline-2,3-dione) 是一种有效的单胺氧化酶 (MAO) 抑制剂，IC50 为 3 μM。
GC16517 Eugenol
丁香酚
丁香酚是一种存在于丁香中的精油，具有抗菌、驱虫和抗氧化活性。
GC10042 Vitamin E
天然维生素E
脂溶性维生素
GC10905 Amodiaquine dihydrochloride dihydrate
阿莫地喹盐酸盐; Amodiaquin dihydrochloride dihydrate
A prodrug form of N-desethyl amodiaquine
GC14584 Fenofibric acid
非诺贝特酸; FNF acid
An agonist of PPARα, PPARγ, and PPARδ and an active metabolite of fenofibrate
GC11567 Acetazolamide
乙酰唑胺
An Analytical Reference Standard
GC17914 Fomepizole
甲吡唑; 4-Methylpyrazole
An alcohol dehydrogenase inhibitor
GC11149 L-a-Hydroxyglutaric acid disodium salt
S-2-羟基戊二酸,(S)-2-Hydroxyglutaric acid disodium
An α-hydroxy acid
GC14713 3-Deazaadenosine
3-脱氮腺苷
3-Deazaadenosine（盐酸盐）是 S-腺苷高半胱氨酸水解酶的抑制剂，Ki 为 3.9 µM。
GC12351 Zaragozic Acid A
萨拉哥酸A,Squalestatin S1
A squalene synthase inhibitor
GC15738 BVT 2733 An 11β-HSD1 inhibitor
GC12431 RSL3
(1S,3R)-RSL3
RSL3被认为是一种强效的诱导铁死亡剂，其作用依赖于GPX4的活性。
GC15037 Sildenafil mesylate
甲磺酸西地那非
A PDE5 inhibitor
GC14187 GW 6471 GW 6471 是一种有效的双重 PPARα/γ 拮抗剂，其具有体内外抗增殖活性。GW 6471与 PPARα 和 PPARγ 的结合亲和力的IC₅₀ 值分别为95.3 ± 42.0 nM 和39.4 ± 18.2 nM。GW 6471可用于癌症的研究。
GC13554 Deferoxamine mesylate
甲磺酸去铁胺; Desferrioxamine B mesylate; DFOM
Deferoxamine mesylate 是一种通过形成稳定的复合物来螯合铁的药物，该复合物可防止铁进入进一步的化学反应，并用于治疗输血依赖性贫血患者的慢性铁过载。