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Home >> Signaling Pathways >> Metabolism

Metabolism(代谢)

  1. Cat.No. 产品名称 Information
  2. GC12824 Dibutyryl-cAMP, sodium salt

    Dibutyryl cAMP sodium salt; DBcAMP sodium salt

     Dibutyryl-cAMP, sodium salt，又称为Bucladesine，是一种细胞膜可透性环核苷酸类似物，能模拟内源性cAMP的作用，并作为磷酸二酯酶抑制剂。
  3. GC17377 Clofibrate

    氯贝丁酯

     A selective PPARα agonist
  4. GC15921 A939572

    4-(2-氯苯氧基)-N-[3-[(甲胺基)羰基]苯基]-1-哌啶羧胺

     A stearoyl-CoA desaturase 1 inhibitor
  5. GC13556 VER-49009

    CCT 129397

     An Hsp90 inhibitor
  6. GC10501 VER-50589 Inhibitor of Hsp90
  7. GC15544 AP-III-a4

    ENOblock

     A small molecule enolase inhibitor
  8. GC17995 Tacrolimus monohydrate

    他克莫司一水合物; FK506 monohydrate; Fujimycin monohydrate; FR900506 monohydrate

     他克莫司一水合物 (FK506 monohydrate) 是一种大环内酯，与 FK506 结合蛋白 (FKBP) 结合形成复合物并抑制钙调神经磷酸酶，从而抑制 T 淋巴细胞信号转导和 IL-2 转录。
  9. GC13287 Udenafil

    乌地那非; DA8159

     A PDE5 inhibitor
  10. GC10451 U-73122

    1-[6-[((17Β)-3-雌酮-1,3,5[10]-三烯-17-基)氨基]乙基]-1H-吡咯-2,5-二酮

     U-73122是有效的、选择性的磷脂酶C（PLC）抑制剂，IC50值约为1-2.1µM，也可抑制5-脂氧合酶（5-LO）。
  11. GC13191 Irsogladine

    伊索拉定; Dicloguamine

     A gastroprotective agent
  12. GC17673 Dipyridamole

    双嘧达莫

     A PDE5A inhibitor
  13. GC15972 Idebenone

    艾地苯醌

     An analog of CoQ10 with neuroprotective effects
  14. GC10132 Ciclopirox

    环吡酮胺; HOE296b

     An iron chelator, antifungal, and anticancer agent
  15. GC11352 Tetramisole HCl

    盐酸四咪唑; (±)-Tetramisole hydrochloride; DL-Tetramisole hydrochloride; R-829

     Tetramisole HCl 是一种碱性磷酸酶抑制剂，是一种高纯度的抗寄生虫药。
  16. GC14046 Methyclothiazide

    甲氯噻嗪

     A thiazide diuretic
  17. GC12992 Fluorometholone Acetate

    氟米龙醋酸酯

     A synthetic glucocorticoid
  18. GC13444 Doxofylline

    多索茶碱

     A bronchodilator
  19. GC18101 Deferiprone

    去铁酮

     An iron chelator
  20. GC15810 Clinofibrate

    克利贝特,S-8527

     A hypolipidemic agent
  21. GC11120 Ciclopirox ethanolamine

    环吡酮乙醇胺盐; Ciclopirox ethanolamine; HOE 296

     An iron chelator, antifungal, and anticancer agent
  22. GC16751 Chlorzoxazone

    氯唑沙宗

     A centrally acting muscle relaxant
  23. GC17341 Carprofen

    卡洛芬

     An NSAID used in animals
  24. GC14543 Bezafibrate

    苯扎贝特; BM15075

     A non-selective PPAR agonist
  25. GC14915 Gemfibrozil

    吉非罗齐; CI-719

     A PPARα and PPARγ agonist
  26. GC17422 Pimobendan hydrochloride

    盐酸匹莫苯丹; UD-CG115 hydrochloride

     An inhibitor of PDE3
  27. GC13870 Pravastatin

    普伐他汀; CS-514

     A potent HMG-CoA reductase inhibitor
  28. GC11332 Pitavastatin

    匹伐他汀; NK-104

     Pitavastatin (NK-104) 是一种有效的羟甲基戊二酰辅酶A (HMG-CoA) 还原酶抑制剂。
  29. GC13932 Dorzolamide

    多佐胺; L671152; MK507

     An Analytical Reference Standard
  30. GC12404 (+)-Ketoconazole

    酮康唑

     A triazole antifungal agent
  31. GC16359 Rosuvastatin

    瑞舒伐他汀; ZD 4522

     An HMG-CoA reductase inhibitor
  32. GC12301 Mizoribine

    咪唑立宾; NSC 289637; HE 69

     An imidazole nucleoside with immunosuppressive properties
  33. GC11895 Mevastatin

    美伐他汀; Compactin; ML236B

     An HMG-CoA reductase inhibitor
  34. GC11816 Posaconazole hydrate

    泊沙康唑水合物; SCH56592 hydrate

     An antifungal agent
  35. GC12250 Fenofibrate

    非诺贝特

     A PPARα agonist
  36. GC12698 BAY 87-2243 A mitochondrial complex I inhibitor and inducer of ferroptosis
  37. GC12880 GSK 2830371 An inhibitor of Wip1 phosphatase
  38. GC12060 Deltarasin hydrochloride A KRAS inhibitor
  39. GC17331 Salubrinal Salubrinal是有效的选择性真核翻译起始因子2α（eIF2α）去磷酸化抑制剂。
  40. GC12356 Glibenclamide

    格列本脲

     格列本脲 (Glyburide) 是一种具有口服活性的 ATP 敏感性 K+ 通道 (KATP) 抑制剂，可用于糖尿病和肥胖症的研究。
  41. GC16607 Mesalamine

    5-氨基水杨酸; Mesalamine; 5-ASA; Mesalazine

     An NSAID and active metabolite of sulfasalazine, balsalazide, and olsalazine
  42. GC14868 Milrinone

    米力农; Win 47203

     An inhibitor of PDE3
  43. GC13083 Siramesine

    Lu 28-179

     A selective σ2 receptor agonist
  44. GC14435 Zileuton sodium

    齐留通钠盐; A 64077 sodium; Abbott 64077 sodium

     A reversible inhibitor of 5-lipoxygenase
  45. GC14948 Pioglitazone

    吡格列酮; U 72107

     Pioglitazone属于格列酮类或噻唑烷二酮类,是一系列口服降糖药。
  46. GC11669 Tamoxifen Citrate

    他莫昔芬柠檬酸盐; ICI 46474; (Z)-Tamoxifen Citrate; trans-Tamoxifen Citrate

     A selective estrogen receptor modulator
  47. GC16233 Tacrolimus (FK506)

    他克莫司; FK506; Fujimycin; FR900506

     他克莫司 (FK506) 是一种具有强效免疫抑制作用的大环内酯类抗生素，从筑波链霉菌中分离出来，以前曾用于预防人类同种异体移植和治疗自身免疫性疾病。
  48. GC17572 Finasteride acetate

    醋酸非那雄胺; MK-906 acetate

     An inhibitor of 5α-reductase type II
  49. GC13124 LY2608204

    (1R,2S)-2-环己基-1-[4-(环丙基磺酰基)苯基]-N-[5-[[2-(1-吡咯烷基)乙基]硫代]-2-噻唑基]环丙烷甲酰胺,LY2608204

     An activator of glucokinase
  50. GC16658 Vinpocetine

    长春西汀; Ethyl apovincaminate

     An inhibitor of PDE1
  51. GC15242 Vardenafil

    伐地那非

     Vardenafil 是一种具有口服活性的选择性磷酸二酯酶 5 (PDE5) 抑制剂，IC50 为 0.7 nM。

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