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Home >> Signaling Pathways >> Metabolism

Metabolism(代谢)

  1. Cat.No. 产品名称 Information
  2. GC91705 Etomidate-d5

    (+)-Etomidate-d5,d-Etomidate-d5,(R)-Etomidate-d5

     Etomidate-d5 is intended for use as an internal standard for the quantification of etomidate by GC- or LC-MS.
  3. GC91691 viFSP1

    Versatile Inhibitor of Ferroptosis Suppressor Protein 1,Versatile Inhibitor of FSP1

     viFSP1 is a species-independent inhibitor of ferroptosis suppressor protein 1 (FSP1; IC50s = 34 and 83 nM for the human and mouse enzymes, respectively).
  4. GC91690 TASP0277308 TASP0277308 is a sphingosine-1-phosphate receptor 1 (S1P1) antagonist (IC50 = 4.2 nM).
  5. GC91667 NSC 44625

    Bendroflumethiazide Impurity A,2,4-Disulfamyl-5-trifluoromethylaniline

     NSC 44625 is an inhibitor of carbonic anhydrase II (CAII; Ki = 63 nM for the human enzyme).
  6. GC91641 4-Hydroxy-1-(2-phenylethyl)piperidine 4-Hydroxy-1-(2-phenylethyl)piperidine is a building block that has been used in the synthesis of ligands of the muscarinic acetylcholine receptor (mAChR) or sigma non-opioid intracellular receptor 1 (σ1 receptor).
  7. GC91623 Ferroptosis Inducer 24 Ferroptosis inducer 24 is an inducer of ferroptosis.
  8. GC91613 FerroLOXIN-1 FerroLOXIN-1 is an inhibitor of the 15-lipoxygenase-2 (15-LO-2) and phosphatidylethanolamine-binding protein 1 (PEBP1) catalytic complex.
  9. GC91598 GPX4 16

    Glutathione Peroxidase 4 16

     GPX4 16 is an inhibitor of glutathione peroxidase 4 (GPX4).
  10. GC91548 Rosuvastatin EP Impurity A (calcium salt) Rosuvastatin EP impurity A is a potential impurity in commercial preparations of the HMG-CoA reductase inhibitor rosuvastatin.
  11. GC91547 Tanzawaic Acid B

    (+)-Tanzawaic Acid B

     Tanzawaic acid B is a fungal metabolite that has been found in Penicillium and has diverse biological activities.
  12. GC91543 (E/Z)-Droloxifene

    3-Hydroxytamoxifen

     (E/Z)-Droloxifene is a mixture of (E)-droloxifene, a selective estrogen receptor modulator (SERM), and (Z)-droloxifene.
  13. GC91499 Voriconazole-d3 N-oxide Voriconazole-d3 N-oxide is intended for use as an internal standard for the quantification of voriconazole N-oxide by GC- or LC-MS.
  14. GC91492 Propiverine N-oxide Propiverine N-oxide is an active metabolite of the muscarinic acetylcholine receptor antagonist propiverine .
  15. GC91489 Chondroitin Sulfate A (sodium salt)

    Chondroitin-4-sulfate,CSA

     Chondroitin sulfate A (CSA) is a glycosaminoglycan.
  16. GC91486 D-(+)-Ribonic Acid γ-lactone

    NSC 1031

     D-(+)-Ribonic acid γ-lactone is an oxidized derivative of ribose and a synthetic material.
  17. GC26431 Pentacosafluorotridecanoic Acid

    全氟十三烷酸，PFTrDA

    Perfluorotridecanoic Acid (Perfluorinated Compound (PFC)) is a perfluorinated alkyl acid (PFAA) and a possible organic pollutant.
  18. GC72637 Hexadecanoate-13C16 potassium Hexadecanoate-13C16 potassium是13C标记的十六烷酸钠。
  19. GC72527 S-(-)-Warfarin
  20. GC72482 Theodrenaline hydrochloride Theodrenaline hydrochloride是一种心脏兴奋剂，也与Cafedrine一起作为降压药。
  21. GC72481 Naveglitazar Naveglitazar（LY519818）是一种非噻唑烷二酮过氧化物酶体增殖物激活受体（PPAR）α-γ双γ显性激动剂，在动物模型中显示出降低血糖的潜力。
  22. GC72438 Osocimab Osocimab (BAY 1213790)，抗fxia抗体(Ki=2.4 nM;EC50 = 0.2海里)。
  23. GC72222 Survodutide Survodutide（BI 456906）是一种强效的选择性胰高血糖素受体/GLP-1受体（GCGR/GLP-1R）双重激动剂，在CHO-K1细胞中的EC50分别为0.52 nM和0.33 nM。
  24. GC72096 Bamadutide Bamadutide（SAR425899）是一种强效的双胰高血糖素样肽-1受体/胰高血糖激素受体激动剂。
  25. GC72078 Azadiradione Azadiradione是在印度印楝中发现的一种生物活性类柠檬素。
  26. GC72068 Batatasin IV Batatasin IV是一种具有抗炎活性的LTA4H抑制剂。
  27. GC72026 Sclareol glycol Sclareol glycol是氨溴化酶的前体。
  28. GC71865 Palmitic acid-13C2 Palmitic acid-13C2是13C标记的棕榈酸。
  29. GC71863 Palmitic acid-13C16 sodium Palmitic acid-13C16 sodium是13C标记的棕榈酸钠。
  30. GC71840 L-Cystine-34S2 L-Cystine-34S2是34S标记的L-胱氨酸。
  31. GC71839 L-Cystine-d4

    L-Cystine-d4是氘标记的L-胱氨酸。
  32. GC71837 L-Glutamine-13C5,15N2,d5 L-Glutamine-13C5,15N2,d5是氘、13C-和15-标记的L-谷氨酰胺。
  33. GC71789 ZY-1 ZY-1是ZY-2的控制分子。
  34. GC71730 L-Glutathione reduced-13C2,15N L-Glutathione reduced-13C2,15N13C和15N标记的L-谷胱甘肽是否减少。
  35. GC71605 Doxofylline-d6 Doxofylline-d6是氘标记的多索茶碱。
  36. GC71583 Dechloro Rivaroxaban Dechloro Rivaroxaban是一种高度选择性、口服活性的Xa因子抑制剂。
  37. GC71580 Otamixaban hydrochloride Otamixaban hydrochloride是一种强效、选择性、速效、竞争性和可逆的fXa抑制剂（Ki=0.5 nM），可有效抑制游离和凝血酶原酶结合的fXa。
  38. GC71535 Fuzapladib Fuzapladib（IS-741）是一种口服活性白细胞功能相关抗原1型（LFA-1）活化抑制剂，是一种白细胞粘附分子。
  39. GC71531 Ciraparantag acetate Ciraparantag acetate是凝血酶和Xa因子抑制剂。
  40. GC71502 CA/MAO-B-IN-1 CA/MAO-B-IN-1（化合物78）是人脑碳酸酐酶（CA）和单胺氧化酶-B（MAO-B）的双重抑制剂，IC50分别为8.8和7.0 nM。
  41. GC71498 Carbonic anhydrase inhibitor 16 Carbonic anhydrase inhibitor 16（化合物1）是一种登革热蛋白酶抑制剂，对碳酸酐酶hCA I和hCA II具有抑制活性（Ki:28.5 nM，2.2 nM）。
  42. GC71411 Dasatinib analog-1 Dasatinib analog-1（化合物5826）抑制CYP3A4的活性，Ki值为5.4μM。
  43. GC71393 Opevesostat Opevesostat是一种胆固醇侧链裂解酶(CYP11A1)抑制剂。
  44. GC71367 PPARγ-IN-2 PPARγ-IN-2（化合物5a）是PPARγ抑制剂。
  45. GC71356 PDE4-IN-14 PDE4-IN-14（化合物1）是一种PDE4抑制剂，可用于研究PDE4相关疾病（如炎性和免疫性疾病、癌症和代谢性疾病等）。
  46. GC71354 VU533 VU533（APE-PLD）激活剂是一种强效的NAPE-PLD激活剂，EC50值为0.30µM。 
  47. GC71353 VU534 VU534是一种NAPE-PLD活化剂，EC50为0.30 μM。
  48. GC71329 A3373 A3373是磷脂酶D1（PLD1）和PLD2的新型化学抑制剂，IC50分别为325 nM和15.15μM，可抑制LPS诱导的免疫反应。
  49. GC71316 SSI-4 SSI-4是硬脂酰辅酶a去饱和酶1 (SCD1)的抑制剂，可以用11C修饰，用作SCD1体内小动物PET/CT成像的配体。
  50. GC71313 hCYP3A4 Fluorogenic substrate 1 hCYP3A4 Fluorogenic substrate 1是波特波特hCYP3A4荧光底物，Km值为0.36 μM。
  51. GC71270 CH3OCO-D-CHA-Gly-Arg-pNA acetate CH3OCO-D-CHA-Gly-Arg-pNA acetate是Xa因子的显色底物。

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