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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel(跨膜转运)

Cat.No. 产品名称 Information
GC14157 (-)-Lobeline hydrochloride
盐酸洛贝林; α-Lobeline hydrochloride; L-Lobeline hydrochloride
An alkaloid with diverse biological activities
GC15416 2-Methylthioadenosine triphosphate tetrasodium salt 2-Methylthioadenosine triphosphate tetrasodium salt 是一种非特异性 P2 受体激动剂。
GC14811 MPDC MPDC 是前脑突触体中 Na+- 依赖性高亲和力谷氨酸转运蛋白的强效和竞争性抑制剂。
GC11598 Diazoxide
二氮嗪; Sch-6783; SRG-95213
An activator of SUR1/K_ir6.2
GC10392 9-AC
9-蒽甲酸
A chloride channel inhibitor
GC10866 Spermidine trihydrochloride
三盐酸亚精胺
An endogenous polyamine
GC11064 Spermine tetrahydrochloride
精胺四盐酸盐
A natural polyamine
GC10943 AM 92016 hydrochloride
N-[4-[3-[[2-(3,4-二氯苯基)乙基]甲基氨基]-2-羟基丙氧基]苯基]甲磺酰胺盐酸盐
An I_Kr inhibitor
GC13947 Evans Blue tetrasodium salt
伊文思蓝; Direct Blue 53; C.I. 23860
Evans Blue tetrasodium salt是一种高效的囊泡谷氨酸吸收抑制剂（IC₅₀=87nM）。
GC10786 DHBP dibromide
二溴化-1,1ˊ-二庚基-4,4ˊ-联吡啶鎓,Diheptylviologen dibromide
DHBP 二溴化物是一种钙释放抑制剂和一种肌肉松弛剂。
GC16915 (2R,3S)-Chlorpheg NMDA receptor antagonist
GC10856 THIP hydrochloride
GAB氧杂DOL盐酸盐
A GABA_A receptor agonist and GABA_C receptor antagonist
GC14410 (±)-Epibatidine
CMI 545
An agonist of α4β2 subunit-containing nAChRs
GC14268 NPPB
NPPB是一种强效的氯通道抑制剂，对短路电流的IC₅₀为80nM。
GC12568 FG 7142
ZK 39106; LSU-65
A benzodiazepine receptor ligand
GC15868 Dantrolene, sodium salt
丹曲林钠,F 440
An inhibitor of calcium release
GC10530 Dihydroergotoxine mesylate
甲磺酸二氢麦角碱; Ergoloid mesylates
A mixture of alkaloids with diverse biological activities
GC15863 Dilazep dihydrochloride
地拉卓二盐酸盐
An ENT1 inhibitor
GC14470 Arcaine sulfate
硫酸魁蛤素
An NMDA receptor antagonist
GC11178 A-7 hydrochloride A cell-permeable antagonist of calmodulin
GC17496 W-7 hydrochloride
N-(6-氨基己基)-5-氯-1-萘磺胺盐酸盐
A cell-permeable antagonist of calmodulin
GC16962 W-5 hydrochloride
W-5盐酸盐
A low-affinity calmodulin antagonist
GC17652 N-(4-Hydroxyphenylacetyl)spermine NMDA receptor antagonist
GC11715 Ibotenic acid
鹅膏氨酸,(RS)-Ibotenic acid; DL-Ibotenic acid
Ibotenic acid是一种神经毒素，对N-甲基-D-天冬氨酸（NMDA）和反式ACPD或代谢使君子酸（Qm）受体位点均具有激动剂活性。
GC11286 ACBC
1-氨基环丁烷羧酸
ACBC 是一种 NMDA 受体部分激动剂，作用于甘氨酸位点 NR1。
GC11071 (R)-AMPA inactive enantiomer of AMPA
GC14834 (±)-Nipecotic acid
3-哌啶甲酸; (±)-β-Homoproline; Hexahydronicotinic acid; 3-Carboxypiperidine
A GAT inhibitor
GC13567 Isoguvacine hydrochloride
异四氢烟酸
A GABA_A receptor agonist
GC14659 Guvacine hydrochloride
去甲槟榔次碱
An inhibitor of GABA uptake
GC14547 Quinolinic acid
喹啉酸
An excitotoxic agonist at NMDA receptors
GC17823 L-Cysteinesulfinic acid
L-半胱氨酸亚磺酸
L-半胱氨酸亚磺酸是几种大鼠代谢型谷氨酸受体 (mGluR) 的有效激动剂，对 mGluR1、mGluR5、mGluR2、mGluR4、mGluR6 和 mGluR8 的 pEC50 分别为 3.92、4.6、3.9、2.7、4.0 和 3.94 .
GC14943 Hypotaurine
亚牛磺酸; 2-Aminoethanesulfinic acid
Hypotaurine是牛磺酸生物合成的前体，是甘氨酸受体（glycine receptor）的内源性抑制性氨基酸。
GC17646 L-(-)-threo-3-Hydroxyaspartic acid
L(-)-THREO-3-羟基天冬氨酸

EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor
GC18033 γDGG
Γ-D-谷氨酰基甘氨酸,γDGG; γ-D-Glutamylglycine
γDGG 是一种竞争性 AMPA 受体阻滞剂。
GC12718 Pantoprazole
泮托拉唑; BY1023; SKF96022
A proton pump inhibitor
GC13010 LY451395
LY451395
LY451395 (LY451395) 是一种有效且高度选择性的 AMPA 受体增强剂。
GC12769 Nonivamide
辣椒素,Pelargonic acid vanillylamide; Nonanoic acid vanillylamide; Pseudocapsaicin
A TRPV1 agonist
GC13672 Tetrabenazine
(+)-丁苯那嗪; (+)-TBZ; (3R,11bR)-TBZ; (3R,11bR)-Tetrabenazine
丁苯那嗪是美国食品和药物管理局唯一批准的亨廷顿舞蹈病药物，适用于治疗与亨廷顿舞蹈病相关的舞蹈症。
GC17469 4-Aminopyridine
4-AP, BRL 34915, Dalfampridine, Fampridine, NSC 15041

potassium channel-blocking agent
GC13869 Fasudil
法舒地尔; HA-1077; AT877
Fasudil（法舒地尔；HA-1077；AT877）是一种非特异性RhoA/ROCK抑制剂，对ROCK1的K_i为0.33μM，IC₅₀为0.158μM，对ROCK2和PKA、PKC、PKG的IC₅₀分别为4.58μM、12.30μM、1.650μM。
GC17616 PPQ-102
CFTR Inhibitor
A CFTR channel inhibitor
GC10186 Tiagabine
噻加宾
A GAT-1 inhibitor
GC13809 Eslicarbazepine acetate
艾司利卡西平醋酸酯,BIA 2-093
A sodium channel blocker
GC17625 Lercanidipine
乐卡地平
乐卡地平是一种亲脂性第三代二氢吡啶-钙通道阻滞剂（DHP-CCB）。
GC10590 Lercanidipine hydrochloride
盐酸乐卡地平
An L-type calcium channel blocker
GC16645 Rabeprazole
雷贝拉唑; LY307640
雷贝拉唑 (LY307640) 是第二代质子泵抑制剂 (PPI)，可不可逆地灭活胃 H+/K+-ATPase。
GC15670 Rabeprazole sodium
雷贝拉唑钠; LY307640 sodium
A proton pump inhibitor
GC17402 Tiagabine hydrochloride
盐酸噻加宾; NO050328 hydrochloride; NO328 hydrochloride; TGB hydrochloride
A GAT-1 inhibitor
GC10579 Ouabain Octahydrate
乌本(箭毒)苷,哇巴因,Acocantherine; G-Strophanthin
Ouabain Octahydrate是一种Na⁺/K⁺-ATPase抑制剂，能够用于研究充血性心力衰竭。
GC13387 Vigabatrin Hydrochloride
盐酸氨己烯酸; γ-Vinyl-GABA hydrochloride
Inhibitor of GABA transaminase