Cell Cycle/Checkpoint(细胞周期/检查点)

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for Cell Cycle/Checkpoint

Cat.No. 产品名称 Information
GC18449 Cardanol monoene
腰果酚(C15:1),Cardanol C15
An inhibitor of tyrosinase with anticancer properties
GC18445 N-Deacetylcolchicine
NSC 201400
An inhibitor of microtubule polymerization
GC18437 Alternariol monomethyl ether
交链孢霉甲基醚
A mycotoxin
GC18421 Dabcyl-YVADAPV-EDANS
Dabcyl-ICE-EDANS
A fluorogenic substrate for caspase-1
GC18408 BML-278
DIETHYL1-BENZYL-4-PHENYL-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE锛圵S201542锛,WUXIAPPTEC"
An activator of SIRT1, SIRT2, and SIRT3
GC18386 Aloisine RP106
7-丁基-6-(4-甲氧基苯基)-5H-吡咯并[2,3-B]吡嗪
An inhibitor of Cdk1, Cdk5, and GSK3
GC18363 Mca-DEVDAPK(Dnp)-OH
Caspase-3 Fluorogenic Substrate III, CPP32 Fluorogenic Substrate III, 7-Methoxycoumarin-4-acetyl-DEVDAPK(Dnp)-OH, Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH
A caspase-3 fluorogenic substrate
GC18359 4-Epianhydrochlortetracycline (hydrochloride)
4-差向四环素盐酸盐
An inhibitor of MMP-9
GC18353 Prostaglandin A2
前列腺素A2,Medullin
A naturally occurring prostaglandin with antiviral/antitumor activity
GC18345 Leptomycin A
来普霉素A
An inhibitor of nuclear transport
GC18315 Calpain Inhibitor VI
SJA6017
A calpain and cathepsin inhibitor
GC18278 NU 6102
4-[[6-(环己基甲氧基)-1H-嘌呤-2-基]氨基]苯磺酰胺
A potent Cdk1 and Cdk2 inhibitor
GC18275 1,2-Dihexadecyl-sn-glycero-3-PC
1,2-十六烷基卵磷脂
A synthetic ether-linked phospholipid
GC18274 Amiprofos-methyl
甲基胺草磷,BAY-NTN 6867
An herbicide
GC18226 Ac-LEHD-AMC (trifluoroacetate salt)
Ac-Leu-Glu-His-Asp-AMC, Caspase-9 Substrate
A caspase-9 fluorogenic substrate
GC18218 MMP-3 Inhibitor
Matrix Metalloproteinase-3 Inhibitor
A peptide inhibitor of MMP-3
GC18165 EMD534085
N-[2-(二甲基氨基)乙基]-N'-[[(2R,4AS,5R,10BS)-3,4,4A,5,6,10B-六氢-5-苯基-9-(三氟甲基)-2H-吡喃并[3,2-C]喹啉-2-基]甲基]脲
An Eg5 inhibitor
GC15171 Ac-LEVD-AFC
Ac-Leu-Glu-Val-Asp-AFC, Ac-Leu-Glu-Val-Asp-7-amino-4-trifluormethylcoumarin
A fluorogenic substrate for caspase-4
GC13400 Ac-VDVAD-AFC
N-Acetyl-Val-Asp-Val-Ala-Asp-7-amino-4-Trifluoromethylcoumarin Caspase-2 Substrate (Fluorogenic)
A fluorogenic substrate for caspase-2
GC13859 Z-DEVD-AFC
Caspase-3 Fluorogenic Substrate IV
A caspase-3 fluorogenic substrate
GC14497 (S)-CCG-1423 A stereoisomer of CCG-1423, a Rho inhibitor
GC10419 (R)-CCG-1423 A stereoisomer of CCG-1423, a Rho inhibitor
GC14918 10074-G5
N-2-联苯基-7-硝基-2,1,3-苯并恶二唑-4-胺
An inhibitor of c-Myc/Max dimerization
GC13606 CFI-400945
orally available, selective inhibitor of polo-like kinase 4 (PLK4)
GC10681 Eg5-I A potent inhibitor of Eg5
GC15841 Alsterpaullone
阿特波龙,9-Nitropaullone,NSC 705701
A dual CDK and GSK3 inhibitor
GC12352 cis-trismethoxy Resveratrol
顺式白藜芦醇三甲醚,cis-Trimethoxy Stilbene
Potent antineoplastic agent
GC15592 Moniliformin (sodium salt)
串珠镰刀菌素钠盐
A mycotoxin
GC13096 MLS-573151
MLS000573151
A specific inhibitor of Cdc42
GC12314 3-(4-Pyridyl)indole
Rho Kinase Inhibitor III,ROCK Inhibitor III,Rockout
A ROCK1 and ROCK2 inhibitor
GC10870 Cytochalasin J
细胞松驰素J
An inhibitor of actin polymerization
GC15514 Phomopsin A
促微管解聚 A
A β-tubulin inhibitor
GC16520 Olomoucine
2-(2'-羟基乙基氨基)-9-甲基-6-(苄基氨基)嘌呤
An inhibitor of cyclin-dependent kinases
GC17649 Mebendazole
甲苯咪唑
A broad-spectrum anthelmintic that inhibits microtubules
GC14986 CCG-100602 A Rho/MKL1 transcriptional pathway inhibitor
GC15215 Iso-Olomoucine
异奥罗莫星
An inactive stereoisomer of olomoucine
GC14294 Cdk1/2 Inhibitor III
Cyclin-dependent kinase 1/2 Inhibitor III
A cell-permeable inhibitor of Cdk1 and Cdk2
GC12319 Ferulenol
阿魏醇
A prenylated 4-hydroxycoumarin
GC11564 Cdk4/6 Inhibitor IV
CINK4
A cell-permeable inhibitor of Cdk4/6
GC14186 3MB-PP1
4-氨基-1-叔丁基-3-(3-甲基苄基)吡唑并[3,4-D]嘧啶
An inhibitor of analog-sensitive Plk1 alleles
GC16265 RS-1
4-溴-N-(4-溴苯基)-3-[[(苯基甲基)氨基]磺酰基]苯甲酰胺
A RAD51 activator
GC14413 KJ Pyr 9 An inhibitor of c-Myc and v-Myc interaction with Max
GC11022 SB 218078 A potent Chk1 inhibitor
GC11593 AZD0156 An ATM kinase inhibitor
GC10716 Netarsudil (AR-13324)
2,4-二甲基苯甲酸[4-[(1S)-1-(氨基甲基)-2-(6-异喹啉基氨基)-2-氧代乙基]苯基]甲基酯二盐酸盐
ROCK抑制剂
GC15607 ON123300
8-环戊基-7,8-二氢-2-[[4-(4-甲基-1-哌嗪基)苯基]氨基]-7-氧代-吡啶并[2,3-D]嘧啶-6-甲腈,ON123300
A multi-kinase inhibitor
GC10251 FRAX1036 A selective PAK1 inhibitor
GC16075 FRAX486 A group I PAK inhibitor
GC16692 Casin
Pirl1-related Compound 2
A Cdc42 GTPase inhibitor
GC14002 Bohemine A Cdk inhibitor