Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC14105 Alprenolol hydrochloride
盐酸阿普洛尔; (RS)-Alprenolol hydrochloride; dl-Alprenolol hydrochloride
A non-selective β-AR and 5-HT receptor antagonist
GC13349 Naspm trihydrochloride
N-[3-[[4-[(3-氨基丙基)氨基]丁基]氨基]丙基]-1-萘乙酰胺三盐酸盐,1-Naphthylacetyl spermine trihydrochloride
A synthetic analog of Joro spider toxin
GC14342 Sazetidine A dihydrochloride α4β2 nicotinic acetylcholine receptor ligand
GC14326 Calmidazolium chloride
钙调蛋白抑制剂,R 24571
An inhibitor of calmodulin
GC16267 6-Hydroxydopamine hydrobromide
6-羟基多巴胺氢溴酸盐; 6-Hydroxydopamine hydrobromide; 6-OHDA hydrobromide
6-Hydroxydopamine hydrobromide (6-OHDA) 是儿茶酚胺、多巴胺和去甲肾上腺素的结构类似物，对儿茶酚胺能神经元发挥毒性作用。
GC12224 L-BMAA hydrochloride
L-BMAA盐酸盐,BMAA hydrochloride
A neurotoxic non-proteinogenic amino acid
GC12056 J 104129 fumarate M3 muscarinic receptor antagonist
GC11001 2-Pyridylethylamine dihydrochloride 组胺 H1 受体激动剂
GC12749 Conessine
地麻素
A steroidal alkaloid with diverse biological activities
GC12814 SDZ NKT 343 SDZ NKT 343 是一种选择性的、口服活性的 NK1 受体拮抗剂，对人 NK1 受体的 IC50 为 0.62 nM。
GC16911 CGS 9343B
CGS-9343B; KW 5617
A calmodulin inhibitor
GC13995 Carcinine ditrifluoroacetate
N-2-[(4-1H-咪唑基)乙基]-3-氨基丙酰胺二盐酸盐
H3 receptor antagonist
GC13573 Nomifensine
诺米芬辛; (±)-Nomifensin
An inhibitor of norepinephrine and dopamine reuptake
GC17854 PNU 142633 PNU 142633 是一种高亲和力、选择性和口服活性的 5-HT1D 受体激动剂，对人 5-HT1D 受体和人 5-HT1B 受体的 Kis 分别为 6 nM 和 \u003e 18 000 nM。
GC12432 (+)-Anabasine hydrochloride
(+)-假木贼碱盐酸盐; (S)-Anabasine hydrochloride; (+)-Anabasine hydrochloride
Anabasine ((S)-Anabasine) hydrochloride 是一种生物碱，在烟草 (Nicotiana) 中是一种微量成分。
GC11385 G-Protein antagonist peptide G-蛋白拮抗肽是抑制G蛋白与其受体结合的P物质相关肽。
GC11362 K 252a
SF 2370
A non-selective PKC inhibitor
GC17890 LE 300 A dopamine D₁-like and 5-HT_2A receptor antagonist
GC15122 [bAla8]-Neurokinin A(4-10)
MEN 10210
[bAla8]-Neurokinin A(4-10) 是一种神经激肽 2 (NK2) 受体激动剂。
GC17547 MEN 10376
Neurokinin-2 receptor antagonist
An NK₂ receptor antagonist
GC11801 Neurokinin B (human, porcine)
神经激肽 B

Neurokinin B (human, porcine) 属于肽的速激肽家族。
GC15634 SC 560
5-(4-氯苯基)-1-(4-甲氧基苯基)-3-(三氟甲基)-1H-吡唑
A selective inhibitor of COX-1
GC14225 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative Precursor to ligand for the α4β2 nicotinic receptor
GC17192 Quinelorane hydrochloride
LY163502
Quinelorane hydrochloride (LY163502) 是一种有效的多巴胺 D3/D2 受体激动剂。
GC11626 5-Iodo-A-85380 dihydrochloride α4β2 and α6β2 nicotinic acetylcholine receptors agonist
GC13610 [Sar9,Met(O2)11]-Substance P
精氨酰-脯氨酰-赖氨酰-脯氨酰-谷氨酰-谷氨酰-苯丙氨酰-苯丙氨酰-SAR-亮氨酸-蛋氨酸[O2]-胺
A peptide NK₁ receptor agonist
GC15649 Substance P
P物质; Neurokinin P
An endogenous NK₁ receptor agonist
GC11738 Neurokinin A (porcine)
神经激肽A,Substance K; Neurokinin α; Neuromedin L
神经激肽 A（猪）（物质 K）是速激肽家族的一种肽神经递质，通过 NK-2 受体起作用。
GC15384 Harmane
哈尔满碱
A β-carboline with diverse biological activities
GC14157 (-)-Lobeline hydrochloride
盐酸洛贝林; α-Lobeline hydrochloride; L-Lobeline hydrochloride
An alkaloid with diverse biological activities
GC13403 Pirenzepine dihydrochloride
盐酸哌仑西平,LS 519; Pirenzepin dihydrochloride; Gastrozepin dihydrochloride
A muscarinic M₁ receptor antagonist
GC14839 Senktide A potent NK3 receptor agonist
GC16463 Oxotremorine M
碘化氧化震颤素M
A muscarinic receptor agonist and KCNQ2/3 potassium channel blocker
GC17734 Pindolol
吲哚洛尔; LB-46
A β₁- and β₂-AR antagonist
GC12813 Tacrine hydrochloride
盐酸他克林
An AChE and butyrylcholinesterase inhibitor
GC14048 SKF 38393 hydrobromide
(±)-SKF-38393 hydrobromide
A partial agonist of dopamine D₁-like receptors
GC10349 (RS)-(±)-Sulpiride
舒必利
An atypical antipsychotic
GC16156 Oxotremorine sesquifumarate
1-(4-[1-吡咯烷基]-2-丁炔基)-2-吡咯烷酮
A muscarinic acetylcholine receptor agonist
GC16162 ICI 162,846
histamine H2 receptor antagonist
GC12774 (±)-Anatoxin A fumarate
(±)-Anatoxin A fumarate 是一种从淡水蓝藻中分离出来的天然生物碱。
GC16052 Aminopotentidine H2 antagonist
GC14410 (±)-Epibatidine
CMI 545
An agonist of α4β2 subunit-containing nAChRs
GC13266 trans-Triprolidine hydrochloride
盐酸曲普利啶
trans-Triprolidine hydrochloride 是一种具有口服活性的组胺 H1 拮抗剂。
GC11291 Mepyramine maleate
吡拉明马来酸盐; Pyrilamine maleate
Mepyramine maleate主要用作H₁拮抗剂，其亲和pK_d为9.4。
GC11128 (±)-Vesamicol hydrochloride
(±)-AH5183 hydrochloride
(±)-Vesamicol hydrochloride ((±)-AH5183 hydrochloride) 是一种有效的囊泡乙酰胆碱转运抑制剂，Ki 为 2 nM。
GC14083 MDL 72222
贝美司琼,MDL 72222
MDL 72222 (MDL 72222) 是一种选择性 5-HT3 受体拮抗剂，IC50 为 0.33 nM。
GC17391 Physostigmine hemisulfate
毒扁豆碱半硫酸盐; Eserine hemisulfate

毒扁豆碱半硫酸盐 (Eserine hemisulfate) 是一种可逆的乙酰胆碱酯酶 (AChE) 抑制剂。
GC14604 5-Methylfurmethiodide
5-甲呋硫碘
muscarinic agonist
GC12568 FG 7142
ZK 39106; LSU-65
A benzodiazepine receptor ligand
GC11883 Dimaprit dihydrochloride
S-(3-二甲氨基丙基)异硫脲二盐酸盐
A histamine H₂ receptor agonist