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Home >> Signaling Pathways >> Neuroscience >> Muscarinic Receptor

Muscarinic Receptor(毒蕈碱受体)

Muscarinic receptor is a group of G-protein coupled receptors that binds to acetylcholine and mediates cellular responses, including inhibition of acetylate cyclase, phosphoinositide degradation and regulation of potassium channels. It is involved in the neurological diseases such as Alzheimer's and Parkinson's.

  1. Cat.No. 产品名称 Information
  2. GC12787 Aceclidine (hydrochloride) A muscarinic receptor agonist
  3. GC10378 N-Isopropylnoratropine An intermediate in the synthesis of ipratropium
  4. GC15758 BQCA A positive allosteric modulator of the M1 mAChR
  5. GC15845 Guvacoline (hydrobromide) A muscarinic receptor agonist
  6. GC12311 Trihexyphenidyl hydrochloride A muscarinic M1 receptor antagonist
  7. GC14508 PTAC oxalate muscarinic receptor ligand
  8. GC17821 VU 0365114 A positive allosteric modulator of muscarinic M5 receptors
  9. GC16655 VU 0357017 hydrochloride An M1 muscarinic acetylcholine receptor agonist
  10. GC10464 VU 0255035 A selective muscarinic M1 receptor antagonist
  11. GC15990 VU 0238429 A muscarinic M5 receptor positive allosteric modulator
  12. GC10725 VU 10010 VU 10010 是一种有效的、高选择性的变构 M4 mAChR 增强剂，EC50 为 400 nM。
  13. GC14619 Milameline hydrochloride Muscarinic receptor agonist
  14. GC18082 Zamifenacin fumarate A muscarinic M3 receptor antagonist
  15. GC13340 AQ-RA 741 M2 antagonist,selective and high affinity
  16. GC10633 DAU 5884 hydrochloride muscarinic M3 receptor antagonist
  17. GC17876 PD 102807 PD 102807 是一种 M4 毒蕈碱受体拮抗剂，IC50 为 90.7 nM。
  18. GC14479 (S)-(+)-Dimethindene maleate (S)-(+)-Dimethindene maleate 是一种对映异构体，是一种有效的 M2 选择性毒蕈碱受体拮抗剂 (pA2 =7.86/7.74; pKi =7.78)。
  19. GC16458 McN-A 343 A partial agonist of muscarinic acetylcholine receptors
  20. GC15510 AF-DX 384 An M2 and M4 muscarinic acetylcholine receptor antagonist
  21. GC13174 Telenzepine dihydrochloride Telenzepine dihydrochloride 是一种选择性和口服活性的毒蕈碱 M1 受体拮抗剂，Ki 为 0.94 nM。
  22. GC10219 AF-DX 116 A muscarinic M2 receptor antagonist
  23. GC13129 W-84 dibromide W-84 (dibromide) 是一种有效的 M2-胆碱受体变构调节剂，可延缓 [3H]N-甲基东莨菪碱的解离。
  24. GC10525 Nitrocaramiphen hydrochloride M1 muscarinic antagonist
  25. GC16504 Arecaidine propargyl ester tosylate muscarinic receptor agonist
  26. GC11415 Arecaidine but-2-ynyl ester tosylate mAChR M2 激动剂
  27. GC10736 (+)-Muscarine iodide 毒蕈碱 ((+)-Muscarine) 碘化物是一种可以刺激副交感神经系统的毒素。
  28. GC12056 J 104129 fumarate M3 muscarinic receptor antagonist
  29. GC13403 Pirenzepine dihydrochloride A muscarinic M1 receptor antagonist
  30. GC16463 Oxotremorine M A muscarinic receptor agonist and KCNQ2/3 potassium channel blocker
  31. GC16156 Oxotremorine sesquifumarate A muscarinic acetylcholine receptor agonist
  32. GC14604 5-Methylfurmethiodide muscarinic agonist
  33. GC13348 4-DAMP An antagonist of the muscarinic M3 receptor
  34. GC16087 Fesoterodine Fumarate A muscarinic acetylcholine receptor antagonist
  35. GC15772 Darifenacin HBr A muscarinic M3 receptor antagonist
  36. GC17182 Solifenacin succinate A muscarinic M1, M2, and M3 receptor antagonist
  37. GC17954 Tolterodine tartrate A muscarinic acetylcholine receptor antagonist
  38. GC14096 Aclidinium Bromide A muscarinic acetylcholine receptor antagonist
  39. GC10621 Biperiden HCl A muscarinic acetylcholine receptor antagonist
  40. GC11831 Umeclidinium bromide A muscarinic acetylcholine receptor antagonist
  41. GC17157 Cevimeline hydrochloride hemihydrate Cevimeline hydrochloride hemihydrate (SNI-2011) 是乙酰胆碱的奎宁环衍生物，是一种选择性和口服活性的毒蕈碱 M1 和 M3 受体激动剂。
  42. GC14215 Cevimeline A muscarinic receptor agonist

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