Home >> Signaling Pathways >> Neuroscience >> Cholecystokinin Receptor

Cholecystokinin Receptor(胆囊收缩素受体)

Cholecystokinin (CCK) is a neuropeptide that affects growth rate in chickens by regulating appetite. CCK peptides exert their function by binding to two identified receptors, CCKAR and CCKBR in the GI tract and the brain, respectively, as well as in other organs. In mammals, CCK/CCKAR interactions affect a number of immunological parameters, including regulation of lymphocytes and functioning of monocytes.

CCK, also known as pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum. The main function of CCK is to cause the release of digestive enzymes and bile from the pancreas and gallbladder, respectively. It also induces drug tolerance to opioids like morphine and heroin. Cholecystokinin (CCK) has strong bioactivity in the regulation of a number of cell activities.

Products for  Cholecystokinin Receptor

  1. Cat.No. 产品名称 Information
  2. GC38746 CCK-B Receptor Antagonist 2 CCK-B Receptor Antagonist 2,化合物 15b,是有效的口服活性 Gastrin/CCK-B 拮抗剂,IC50 值为 0.43 nM。 CCK-B Receptor Antagonist 2 还抑制 Gastrin/CCK-A 活性,IC50 为 1.82 μM。
  3. GA21898 Gastrin I (rat) 胃泌素I(大鼠)(Rat Gastrin-17)是一种肽类激素,能有效刺激胃酸分泌。
  4. GC36976 Proglumide Proglumide 是已知的胆囊收缩素 (CCK) 拮抗剂。
  5. GC36611 Mini Gastrin I, human TFA Mini Gastrin I, human (TFA) 为由 13 个氨基酸组成的短的人胃泌素 (gastrin)。
  6. GC36610 Mini Gastrin I, human Mini Gastrin I, human 为由 13 个氨基酸组成的短的人胃泌素 (gastrin)。
  7. GC35846 Dexloxiglumide A CCK1 receptor antagonist
  8. GC32776 Pentagastrin (ICI-50123) A CCK2 receptor agonist
  9. GC31613 SR 146131

    SR146131是一种有效,有口服活性,选择性的非多肽缩胆囊素1(cholecystokinin1)受体激动剂。

  10. GC31592 GI 181771 GI181771是研究用于治疗肥胖症的胆囊收缩素1(cholecystokinin1)受体激动剂。
  11. GC31558 CCK-A receptor inhibitor 1

    CCK-Areceptorinhibitor1是一种缩胆囊素A(cholecystokininA,CCK-A)受体抑制剂,IC50为340nM。

  12. GC31477 Tarazepide

    Tarazepide是一种有效且特异性的CCK-A受体拮抗剂。

  13. GC31407 Sograzepide (Netazepide) Sograzepide (Netazepide)(Netazepide; YF 476; YM-220) 是一种极有效、高选择性和口服活性的 Gastrin/CCK-B 拮抗剂,IC50 值为 0.1 nM,对 Gastrin/CCK-A 活性有抑制作用,IC50 为 502纳米。
  14. GC31382 Loxiglumide (CR-1505) A CCK receptor antagonist
  15. GC30752 CCK-B Receptor Antagonist 1 CCK-B Receptor Antagonist 1 是胆囊收缩素 B (CCK-B) 受体的拮抗剂,具有减少胃酸分泌的潜力。
  16. GC30680 Gastrin/CCK antagonist 1

    Gastrin/CCKantagonist1是gastrin/CCK的拮抗剂,可用于肠胃失调疾病的研究。

  17. GC30674 CHEMBL333994 (FK-480) CHEMBL333994 (FK-480) 是一种有效的口服有效的胆囊收缩素 A (CCK-A) 拮抗剂,IC50 为 0.67 nM。
  18. GC30008 Ceruletide (Caerulein) Ceruletide (Caerulein) 是一种十肽和有效的胆囊收缩素受体激动剂。
  19. GC19258 Nastorazepide Nastorazepide (Z-360) 是一种选择性的口服 1,5-苯二氮卓衍生物胃泌素/胆囊收缩素 2 (CCK-2) 受体拮抗剂,具有潜在的抗肿瘤活性。
  20. GC10360 Lorglumide (sodium salt) A selective antagonist of CCK1
  21. GC18139 Devazepide Devazepide (L-364,718) 是一种有效、竞争性、选择性和口服活性的胆囊收缩素 (CCK) 受体非肽拮抗剂,对大鼠胰腺、牛胆囊和豚鼠脑 CCK 受体的 IC50 分别为 81 pM、45 pM 和 245 nM .
  22. GC14258 SR 27897 A nonpeptide CCK1 antagonist
  23. GC15133 Gastrin I (human) A peptide hormone
  24. GC11012 Proglumide sodium salt Proglumide sodium salt 是一种非肽类和具有口服活性的胆囊收缩素 (CCK)-A/B 受体拮抗剂。

23 Item(s)

per page

Set Descending Direction