Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC12927 (±)-Baclofen
巴氯芬
A GABA_B receptor agonist
GC14281 L-DOPA methyl ester (hydrochloride)
盐酸左旋多巴甲酯,3,4-Dihydroxyphenylalanine methyl ester,LDME,Levodopa methyl ester,ST 41769
A dopamine precursor
GC14302 9,12-Octadecadiynoic Acid
Ro 3-1314
An inhibitor of both COX and lipoxygenase
GC15105 FPS-ZM1
RAGE Antagonist
FPS-ZM1是一种特异性RAGE抑制剂，K_i值为25nM。
GC13042 Inotilone
(2E)-2-[(3,4-二羟基苯基)亚甲基]-5-甲基-3(2H)-呋喃酮
A COX-2 inhibitor
GC15758 BQCA
1-(4-甲氧基苄基)-4-氧代-1,4-二氢喹啉-3-羧酸
A positive allosteric modulator of the M₁ mAChR
GC16824 Pargyline (hydrochloride)
优降宁盐酸盐；盐酸帕吉林；巴吉林盐酸盐
An irreversible MAO inhibitor
GC10643 Pimozide
匹莫齐特; R6238
A dopamine receptor antagonist
GC13465 Chlorcyclizine (hydrochloride)
盐酸氯环利嗪；盐酸氯环力嗪
A histamine H₁ antagonist
GC11606 4-Methylbenzylidene camphor
4-甲基苄亚基樟脑; 4-MBC; Enzacamene
A UV blocker with estrogenic effects
GC14828 CPHPC
Ro 63-8695|GSK2315698
An inhibitor of the protein-protein interaction between SAP and amyloid fibrils
GC16082 Spinosyn A
多杀霉素 A
A naturally-occurring insecticide
GC14013 Losartan Carboxaldehyde
氯沙坦甲醛,DuP-167|EXP3179
A losartan metabolite with anti-inflammatory actions
GC10231 ZINC12613047 butyrylcholinesterase (BChE) inhibitor
GC13314 L-Acetylcarnitine (hydrochloride)
乙酰左旋肉碱,Acetyl-L-Carnitine,ALCAR
A mitochondrial metabolite
GC17656 Chlorprothixene (hydrochloride)
氯普噻吨盐酸盐；泰尔登盐酸盐；氯丙硫蒽盐酸盐
A dopamine D₂ receptor antagonist
GC11721 Sulindac sulfone
磺基舒林,Exisulind
A metabolite of sulindac
GC15977 (S)-Ketoprofen
(S)-(+)-酮洛芬; (S)-Ketoprofen; Dexketoprofen
A potent inhibitor of COX-1 and COX-2
GC15351 PF-9184 A potent mPGES-1 inhibitor
GC15604 Hydroxytacrine (maleate)
马来酸维吖啶,HP 029,1-Hydroxytacrine,P 83-6029A,Velnacrine
A major active metabolite of tacrine
GC11124 Lanicemine
拉尼西明; AZD6765
A low-trapping NMDA channel blocker
GC11100 Flibanserin
氟立班丝氨; BIMT-17; BIMT-17BS
A 5-HT_1A receptor agonist and 5-HT_2A receptor antagonist
GC15845 Guvacoline (hydrobromide)
氢溴酸胍喹啉,Norarecoline
A muscarinic receptor agonist
GC16782 Benocyclidine
N-[1-(2-苯并[B]噻嗯-2-基)环己基)]哌啶马来酸
An Analytical Reference Standard
GC11098 Verubecestat (MK-8931)
维罗司他; MK-8931
An inhibitor of BACE1 and BACE2
GC12293 Perphenazine
奋乃静
A typical antipsychotic
GC11695 Cinnarizine
桂利嗪
A calcium channel inhibitor and histamine H₄ receptor antagonist
GC12962 Isatin
靛红,Indoline-2,3-dione
Isatin (Indoline-2,3-dione) 是一种有效的单胺氧化酶 (MAO) 抑制剂，IC50 为 3 μM。
GC13757 CarbinoxaMine Maleate
马来酸罗托沙敏
A histamine H₁ receptor antagonist
GC17596 Netupitant
奈妥吡坦; CID 6451149
An NK₁ receptor antagonist
GC11049 (+/-)-Sulfinpyrazone
磺吡酮,G-28315
An inhibitor of uric acid reabsorption
GC15895 Itopride hydrochloride
盐酸伊托必利; HSR803
An AChE inhibitor and a prokinetic agent
GC12591 Diflunisal
二氟尼柳,MK-647
A non-selective COX inhibitor
GC14559 Fluphenazine dihydrochloride
盐酸氟奋乃静
A dopamine D₁ and D₂ receptor antagonist
GC12311 Trihexyphenidyl hydrochloride
盐酸苯海索
A muscarinic M₁ receptor antagonist
GC14584 Fenofibric acid
非诺贝特酸; FNF acid
An agonist of PPARα, PPARγ, and PPARδ and an active metabolite of fenofibrate
GC13746 Fenbufen
芬布芬; CL-82204
An NSAID
GC11143 NS 11394
3'-[5-(1-羟基-1-甲基乙基)-1H-苯并咪唑-1-基]-[1,1'-联苯]-2-甲腈
A subunit-selective positive allosteric modulator of the GABA_A receptor
GC15059 Sulindac sulfide
cis-Sulindac sulfide
An active metabolite of sulindac
GC13554 Deferoxamine mesylate
甲磺酸去铁胺; Desferrioxamine B mesylate; DFOM
Deferoxamine mesylate 是一种通过形成稳定的复合物来螯合铁的药物，该复合物可防止铁进入进一步的化学反应，并用于治疗输血依赖性贫血患者的慢性铁过载。
GC16243 β-Amyloid (1-42), human TFA
大豆肽
淀粉样蛋白 β 肽 (1-42) 人 TFA 是一种由 42 个氨基酸组成的肽。
GC17729 SKF38393 HCl
(±)-SKF-38393 hydrochloride; SKF-38393A
SKF38393 HCl 是一种多巴胺 D1 受体 (D1DR) 的选择性激动剂，IC50 为 110 nM。
GC10743 Cyclobenzaprine HCl
盐酸环苯扎林; MK130 hydrochloride
An Analytical Reference Material
GC17975 Naproxen Sodium
萘普生钠
Naproxen sodium 是一种 COX-1 和 COX-2 抑制剂，在细胞试验中 IC50 分别为 8.72 和 5.15 μM。
GC17258 β-Estradiol - d3
bata-雌二醇,β-Estradiol-d3; 17β-Estradiol-d3; 17β-Oestradiol-d3
β-Estradiol - d3 (β-β-Estradiol - d3) 是氘标记的雌二醇。
GC14130 AZD3839 An inhibitor of BACE1
GC15449 Rolapitant
罗拉匹坦; SCH619734
A potent NK₁ receptor antagonist
GC16931 LED209
N-苯基-4-(3-苯基硫代脲基)苯磺酰胺
A potent inhibitor of virulence gene expression
GC12507 ML352 An inhibitor of the presynaptic choline transporter
GC16634 Sumatriptan
舒马曲坦,GR 43175 free base
An agonist of 5-HT_1B and 5-HT_1D receptors