Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC40142 Lactosylceramides (bovine buttermilk)
乳糖苷
A sphingolipid
GC40132 ACTH (6-24) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
HFRWGKPVGKKRRPVKVYP
A peptide fragment of ACTH
GC40125 Z-VA-DL-D(OMe)-FMK (trifluoroacetate salt)
Caspase-1 Inhibitor V, Z-VAD-FMK, Z-VAD(OMe)-FMK, Z-Val-Ala-DL-Asp(OMe)-Fluoromethyl Ketone
A pan-caspase inhibitor
GC40114 Histone H3K4Me3 (1-10) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt) Histone H3K4Me3 (1-10) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-11 of the human histone H3 sequence.
GC40105 βARK1 Inhibitor
呋喃妥因-13C3
An inhibitor of GRK2/βARK1
GC40078 Memantine-d6 (hydrochloride)
盐酸美金刚 d6 (盐酸盐)
An internal standard for the quantification of memantine
GC40077 Brimonidine-d4
溴莫尼定 d4
An internal standard for the quantification of brimonidine
GC40068 Setosusin
(+)-Setosusin
A fungal metabolite
GC40065 Meloxicam-d3
美洛昔康 d3
An internal standard for the quantification of meloxicam
GC40053 5α,6α-epoxy Cholestanol
胆固醇-5Α,6Α-环氧化物,NSC 18176
5α,6α-epoxy Cholestanol 是一种胆固醇衍生物，可以通过线粒体中的细胞色素P450酶系催化生成或是在脂质过氧化过程中诱导生成，可调节胆汁酸的生物合成、诱导肿瘤细胞的分化和死亡。
GC40045 4-(Dimethylamino)-1-methylpyridinium (iodide) A pyridinium salt
GC40044 Zymostenol
Δ8-Cholesterol
A precursor of cholesterol
GC40043 Totarol
桃柁酚,NSC 299936, (+)-Totarol, trans-Totarol
A diterpene with diverse biological activities
GC40042 Cholesteryl Erucate
胆固醇芥酸甲酯
A cholesterol ester
GC40041 Cholesteryl Lignocerate
24:0 CE, 24:0 Cholesterol ester
A cholesterol ester
GC40027 True Blue
NCI 240899
A fluorescent neuronal retrograde tracer
GC40024 Altenusin
细格菌素,Alutenusin
A fungal metabolite with diverse biological activities
GC40018 Donepezil N-oxide
多奈哌齐N氧化物
An active metabolite of donepezil
GC40016 Ganglioside GM2 Mixture (sodium salt)
单唾液酸神经节苷脂GM2; GM2; Monosialoganglioside GM2
A mixture of ganglioside G_M2
GC34418 Netupitant D6 (CID-6451149 D6) An internal standard for the quantification of netupitant
GC34408 Monohydroxy Netupitant D6 MonohydroxyNetupitantD6是MonohydroxyNetupitant的氘代化合物标准品。
GC34396 Calcitonin Gene Related Peptide (CGRP) (83-119), rat CalcitoninGeneRelatedPeptide(CGRP)(83-119),rat是一种由37个氨基酸组成的降钙素家族神经肽，通过(CRLR)起作用。
GC34395 Calcitonin Gene Related Peptide (CGRP) (83-119), rat TFA CalcitoninGeneRelatedPeptide(CGRP)(83-119),rat(TFA)是一种由37个氨基酸组成的降钙素家族神经肽，通过(CRLR)起作用。
GC34390 Autocamtide 2, amide Autocamtide2,amide是钙调蛋白激酶(CaMK)家族实验的底物(100μMfinalconcentration)。
GC34362 SSD114 hydrochloride SSD114hydrochloride是一种新型GABAB受体正变构调节剂。
GC34352 NMDAR antagonist 1
2,2,2-三氟-N-(丙-2-炔-1-基)乙酰胺
NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective antagonist of NMDAR. It has neuroprotective activity.
GC34338 H3R-IN-1 Hydrochloride H3R-IN-1Hydrochloride是一种有效的组胺受体3(H3R)反向激动剂，详细信息请参考专利文献WO2013107336A1中的化合物2。
GC34304 Befiradol hydrochloride (NLX-112 (hydrochloride)) Befiradolhydrochloride(NLX-112hydrochloride)是选择性的5-羟色胺1A(5-HT)1A受体激动剂。
GC34288 Pyridostigmine D6 bromide
溴化吡啶斯的明 d6 (溴盐)
PyridostigmineD6bromide是Pyridostigmine的氘代化合物标准品。
GC34242 β-Amyloid (1-42), rat TFA β-Amyloid(1-42),ratTFA是由42个氨基酸组成的多肽，对海马切片有毒性，可用于阿尔兹海默症的研究。
GC34232 Beta-Amyloid(1-14),mouse,rat Beta-Amyloid(1-14),mouse,rat是Amyloid-β多肽的1-14片段。
GC34230 Adrenomedullin (1-50), rat Adrenomedullin(1-50),rat是由50个氨基酸组成的多肽，能够通过激活CGRP1受体来诱导动脉血管舒张。
GC34158 RG-12915 RG-12915是一种选择性的5-HT3拮抗剂，IC50值为0.16nM。
GC34116 Hexahydrocurcumin
六氢姜黄素
A natural product and an active metabolite of curcumin
GC34079 Monepantel (AAD1566)
AAD1566
Monepantel (AAD1566) 是一种有机驱虫药，可作为烟碱乙酰胆碱受体 (nAChR) 亚基的线虫特异性进化枝的正变构调节剂。
GC34064 Aminooxyacetic acid hemihydrochloride (Carboxymethoxylamine Hemihydrochloride)
氨氧基乙酸半盐酸盐; Carboxymethoxylamine hemihydrochloride; Aminooxyacetate hemihydrochloride
A GABA-T inhibitor
GC34033 Sulamserod (RS-100302)
RS-100302
Sulamserod (RS-100302) 是一种 5-HT4 受体拮抗剂，具有抗心律失常活性。
GC34028 Nitroflurbiprofen (HCT 1206)
硝基氟比洛芬; HCT 1206; NO-flurbiprofen; Nitroxybutyl flurbiprofen
Nitroflurbiprofen (HCT 1206) 是一种环氧合酶 (COX) 抑制剂，具有提供一氧化氮 (NO) 的特性，可调节门脉高压性肝硬化大鼠肝内血管张力的增加。
GC33983 Amitraz (BTS-27419)
双甲脒; BTS-27419
A formamidine acaricide
GC33893 FR-188582 FR-188582是高选择性的环氧合酶(COX-2)抑制剂，IC50值为17nM。
GC33879 Azelastine
氮卓斯汀
Azelastine HCl is a potent, second-generation, selective, histamine receptor antagonist, used in the treatment of rhinitis.
GC33878 Irsogladine maleate (Dicloguamine maleate)
马来酸伊索拉定; Dicloguamine maleate; MN1695
A gastroprotective agent
GC33876 Propyphenazone (4-Isopropylantipyrine)
异丙安替比林; 4-Isopropylantipyrine; Isopropylphenazone
Propyphenazone(4-Isopropylantipyrine, Isopropyrine), an analgesic and antipyretic agent, is a selective cyclooxygenase-2 inhibitor with anti-inflammatory activity.
GC33861 Inulicin (1-O-Acetylbritannilactone)
旋覆花内酯,1-O-Acetylbritannilactone
A sesquiterpene lactone with diverse biological activities
GC33822 Larazotide acetate
醋酸拉瑞唑来
Larazotide acetate（以前称为 AT-001）是一种高度极性的八肽，来源于霍乱弧菌分泌的原核闭合带蛋白。
GC33775 Rimacalib (SMP 114)
SMP 114
Rimacalib (SMP 114) (SMP 114) 是一种 Ca2+/钙调蛋白依赖性蛋白激酶 II (CaMKII) 抑制剂，IC50 为 ~1 μ；M 代表 CaMKIIα；至 ~30 μ；M 代表 CaMKIIγ；。
GC33754 FG8119 (NNC13-8119)
NNC13-8119
FG8119 (NNC13-8119) 是一种从美国专利 4745112 A 中提取的新型苯二氮卓类激动剂。
GC33751 CGP11952 CGP11952是一种三唑基Benzaphenon。CGP11952是一种苯二氮卓类(benzodiazepine)衍生物。
GC33750 BF-168 BF-168是PET的候选探针，能够特异性识别神经和弥漫性斑块，其对Aβ1-42的Ki值为6.4nM。
GC33749 Salsolidine
猪毛菜定；鹿尾草定
An alkaloid