Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC46010 Opipramol
奥匹哌醇; Ensidon; G-33040
A σ receptor ligand
GC46009 1,2,3-Trioctanoyl-rac-glycerol-13C3
三辛酸甘油酯-1,1,1-13
An internal standard for the quantification of 1,2,3-trioctanoyl glycerol-¹³C₃
GC46007 Cariprazine-d6
卡利拉嗪-D6,RGH-188-d6
An internal standard for the quantification of cariprazine
GC45999 Phentolamine-d4 (hydrochloride) An internal standard for the quantification of phentolamine
GC45998 Mitoxantrone-d8
米托蒽醌-D8,Mitozantrone-d8; NSC 301739-d8
An internal standard for the quantification of mitoxantrone
GC45995 DO264 An ABHD12 inhibitor
GC45991 NCS-382 (sodium salt) A GHB receptor antagonist
GC45987 NS 9283 NS 9283是α4β2亚基烟碱乙酰胆碱受体（nAChR）的阳性变构调节剂。
GC45979 1-Palmitoyl-2-Oleoyl-3-Arachidonoyl-rac-glycerol
1-Palmitin-2-Olein-3-Arachidonin, TG(16:0/18:1/20:4)
A triacylglycerol
GC45965 Tolfenamic Acid-d4
托芬那酸 D4
An internal standard for the quantification of tolfenamic acid
GC45964 (S)-3-N-Cbz-amino-succinimide An anticonvulsant
GC45961 THDOC
3ALPHA,21-二羟基-5ALPHA-孕甾-20-酮,THDOC
A neurosteroid and positive allosteric modulator of GABA_A receptors
GC45945 Trihydroxycholestanoic Acid
粪甾烷酸,Trihydroxycoprostanic Acid
A cholic acid intermediate
GC38829 Osanetant
奥沙奈坦,SR142801
An NK₃ receptor antagonist
GC38828 Org-12962
1-[6-氯-5-(三氟甲基)吡啶-2-基]哌嗪
A 5-HT_2C receptor agonist
GC38806 L-745870 hydrochloride L-745870 hydrochloride 是一种高亲和力，选择性和口服活性的人多巴胺 D4 受体拮抗剂，Ki 为 0.43 nM，而对 D2 (Ki 为 960 nM) 和 D3 (Ki 为 2300 nM) 受体的亲和力相对较弱。L-745870 hydrochloride 具有出色的大脑渗透能力。
GC38805 L-745870
三氢氯酸L-745,870
L-745870 is a high-affinity, selective and orally active antagonist of human dopamine D4 receptor with Ki of 0.43 nM. L-745870 considerably weaker D2 and D3 receptors affinity with Ki of 960 nM and 2300 nM, respectively. L-745870 has excellent brain penetration.
GC38793 Huperzine B
石杉碱乙
An alkaloid with neuroprotective activity
GC38781 Frovatriptan succinate hydrate
罗曲普坦琥珀酸盐,(R)-Frovatriptan succinate hydrate; SB 209509 succinate hydrate; VML 251 succinate hydrate
An agonist of 5-HT_1B and 5-HT_1D receptors
GC38760 Cyamemazine
氰美马嗪
Cyamemazine 是一种抗精神病药，其中含有吩噻嗪发色团，通常被用作抗焦虑药。Cyamemazine 是具有抗精神病活性的有效的 5-HT3 (Ki 为 12 nM), 5-HT2A (Ki 为 1.5 nM) 和 5-HT2C (Ki 为 75 nM) 受体拮抗剂。
GC38758 Clomethiazole
氯美噻唑
Chlormethiazole 是一种有效的口服 GABAA 激动剂。 Chlormethiazole 还可以抑制人肝微粒体中的细胞色素 P450 亚型: CYP2A6 和 CYP2E1。Chlormethiazole 有抗惊厥作用，具有治疗惊厥性癫痫的潜力。
GC38753 cis-Urocanic acid
顺式-尿刊酸; (Z)-Urocanic acid; cis-UCA
cis-Urocanic acid 是一种 5-HT2A 受体激动剂。cis-Urocanic acid 以较高亲和力与 5-HT 受体结合，Kd 为 4.6 nM。cis-Urocanic acid 是一种免疫调节剂，通过与 5-HT2A 受体结合而诱导免疫抑制。
GC38746 CCK-B Receptor Antagonist 2 CCK-B Receptor Antagonist 2，化合物 15b，是有效的口服活性 Gastrin/CCK-B 拮抗剂，IC50 值为 0.43 nM。 CCK-B Receptor Antagonist 2 还抑制 Gastrin/CCK-A 活性，IC50 为 1.82 μM。
GC38732 Acotiamide monohydrochloride trihydrate
盐酸阿考替胺三水合物
Acotiamide Hydrochloride (YM-443, Z-338) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor.
GC45917 Leucettine L41 An inhibitor of DYRK1A, DYRK2, CLK1, and CLK3
GC45911 Zopolrestat
唑泊司他,CP73850
A potent aldose reductase inhibitor
GC45891 Prazosin-d8
哌唑嗪-D8
An internal standard for the quantification of prazosin
GC45879 Palonosetron-d3 (hydrochloride)
盐酸帕洛诺司琼 d3 (盐酸盐)
A neuropeptide with diverse biological activities
GC45838 N,N-Dipropyldopamine (hydrobromide)
N,N-二丙基多巴胺氢溴酸盐
A dopamine receptor agonist
GC45833 N-Oleoyl-L-phenylalanine
18-1-Phe, C18:1-Phe
An N-acyl amide
GC45831 SRI-011381 SRI-011381是一种具口服活性的转化生长因子β（TGF-β）信号通路的激活剂，具有神经保护作用。
GC45824 Netupitant-d6
奈妥吡坦 D6; CID-6451149-d6
An internal standard for the quantification of netupitant
GC45823 Rofecoxib-d5
罗非考昔 d5
An internal standard for the quantification of rofecoxib
GC45820 Balsalazide-d4 Balsalazide-d4 是氘标记的 Balsalazide。
GC45818 Metoclopramide-d3
甲氧氯普安D3
An internal standard for the quantification of metoclopramide
GC45815 Decanoic Acid-d19
癸酸 d19
An internal standard for the quantification of decanoic acid
GC45803 GHRP-2 (trifluoroacetate salt)
D-Ala-3-(2-naphthalenyl)-D-Ala-L-Ala-L-Trp-D-Phe-L-lysinamide, Growth Hormone-Releasing Peptide 2, KP-102, Pralmorelin
A neuropeptide with diverse biological activities
GC45802 Zonisamide-13C2,15N An internal standard for the quantification of zonisamide
GC45801 Hesperetin-13C-d3 A neuropeptide with diverse biological activities
GC45798 Rhein-13C4
1,8-二羟基-3-羧基蒽醌

An internal standard for the quantification of rhein
GC45794 Linaclotide-d4 A neuropeptide with diverse biological activities
GC45791 PF-04995274 A partial 5-HT₄ agonist
GC45787 Moxidectin-d3
CL-301423-d3
A neuropeptide with diverse biological activities
GC45776 LY404187
N-[2-(4'-氰基联苯-4-基)丙基]-2-丙烷磺酰胺
A positive allosteric modulator of AMPA receptors
GC45773 2-chloro-N6-Cyclopentyladenosine (hydrate)
CCPA
A neuropeptide with diverse biological activities
GC45768 Pranlukast-d4
ONO-1078-d4
A neuropeptide with diverse biological activities
GC45765 Deferiprone-d3
去铁酮 d3
An internal standard for the quantification of deferiprone
GC45763 Tolcapone-d4
托卡朋-D4,Ro 40-7592-d4
An internal standard for the quantification of tolcapone
GC45761 Flupirtine-d4 (hydrochloride)
D 9998-d4 hydrochloride
An internal standard for the quantification of flupirtine
GC45756 Pimozide-d4
R6238-d4
An internal standard for the quantification of pimozide