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Cell Cycle/Checkpoint

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for  Cell Cycle/Checkpoint

  1. Cat.No. Product Name Information
  2. GC40702 α-D-Galactopyranosylphenyl isothiocyanate

    α-D-Galactopyranosylphenyl isothiocyanate is a chemically activated form of galactose that has been used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate.

  3. GC41676 (±)-Nornicotine (±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist.
  4. GC49482 (±)-Nornicotine-d4 An internal standard for the quantification of (±)-nornicotine
  5. GC41684 (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (BMC) is a cyclohexane with two mercaptoacetamido groups.
  6. GC40802 (±)12(13)-DiHOME

    (±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.

  7. GC41656 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol 2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system.
  8. GC45890 (+)-Abscisic Acid-d6
  9. GC62728 (1E)-CFI-400437 dihydrochloride (1E)-CFI-400437 dihydrochloride 是一种有效的 PLK4 (IC50= 0.6 nM),并对 PLK 家族的其他成员有选择性 (>10 μM)。(1E)-CFI-400437 dihydrochloride 抑制 Aurora A、 Aurora B、 KDR 和 FLT-3,IC50 分别为 0.37、0.21、0.48 和 0.18 μM。具有抗增殖活性。
  10. GC41268 (E)-2-Hexadecenal Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase.
  11. GC41701 (E)-2-Hexadecenal Alkyne (E)-2-Hexadecenal alkyne is an alkyne version of the sphingolipid degradation product (E)-2-hexadecenal that can be used as a click chemistry probe.
  12. GC46335 (E)-Fenpyroximate
  13. GC10419 (R)-CCG-1423 Rho inhibitor
  14. GC16429 (R)-DRF053 dihydrochloride cdk/CK1 inhibitor,potent and ATP-competitive
  15. GC41719 (R)-nitro-Blebbistatin (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin, which is the inactive form of (-)-blebbistatin.
  16. GC46347 (S)-(+)-Methoprene
  17. GC41557 (S)-3'-amino Blebbistatin (S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
  18. GC41484 (S)-3'-hydroxy Blebbistatin (S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
  19. GC14497 (S)-CCG-1423 Rho inhibitor
  20. GC34999 (S)-Ceralasertib (S)-Ceralasertib 从专利 WO2011154737A1 中获取,化合物 II,IC50 为 2.578 nM。(S)-Ceralasertib 是一种有效的选择性亚砜亚胺吗啉代嘧啶 ATR 抑制剂,具有优异的临床前物化和药代动力学 (PK) 特征。(S)-Ceralasertib 水溶性改善,并且消除 CYP3A4 时间依赖性抑制。
  21. GC46351 (S)-CR8
  22. GC41737 (S)-Glycyl-H-1152 (hydrochloride) Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability.
  23. GC40145 (S)-Laudanosine (S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium.
  24. GC41739 (S)-nitro-Blebbistatin (S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
  25. GC18275 1,2-Dihexadecyl-sn-glycero-3-PC 1,2-Dihexadecyl-sn-glycero-3-PC is a synthetic ether-linked phospholipid containing hexadecyl groups at the sn-1 and sn-2 positions.
  26. GC45783 1,2-Dioleoyl-rac-glycerol-13C3
  27. GC46379 1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)
  28. GC41823 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)

    1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) is a biotinylated phospholipid.

  29. GC46385 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose
  30. GC19528 1,4-Benzoquinone
  31. GC18726 1-Methyl-1,4-dihydronicotinamide 1-Methyl-1,4-dihydronicotinamide is a derivative of nicotinamide .
  32. GC49736 10-acetyl Docetaxel A derivative of paclitaxel and an inhibitor of microtubule depolymerization
  33. GC12954 10-DAB (10-Deacetylbaccatin)

    Precursor of antitumor compound Palitaxel and Docetaxel

  34. GC35044 10-Deacetyl-7-xylosyl paclitaxel 10-Deacetyl-7-xylosyl paclitaxel是Paclitaxel的衍生物,相比Paclitaxel,具有更好的药学活性和水溶性。
  35. GC35045 10-Oxo Docetaxel 10-Oxo Docetaxel (Docetaxel Impurity 1) 是新型紫杉烷,具有明显的抗肿瘤活性,是多西他赛(docetaxel)的中间体。
  36. GC17295 10058-F4 C-Myc-Max dimerization inhibitor
  37. GC63576 10074-A4 10074-A4 是一种 c-Myc 抑制剂,可以在肽链的不同位点与 c-Myc370-409 结合。10074-A4 具有抗癌作用。
  38. GC14918 10074-G5 c-Myc inhibitor
  39. GC40448 12(S)-HETE

    12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.

  40. GC46434 13C15-Nivalenol
  41. GC49390 13C6-4-Nitroaniline An internal standard for the quantification of 4-nitroaniline
  42. GC41110 16-epi Latrunculin B 16-epi Latrunculin B, first isolated from the Red Sea sponge N.
  43. GC48423 19-O-Acetylchaetoglobosin A
  44. GC42151 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) 2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis.
  45. GC40947 2,3-Dimethoxy-5-methyl-p-benzoquinone 2,3-Dimethoxy-5-methyl-p-benzoquinone, also known as coenzyme Q0, is a key intermediate in the synthesis of coenzyme Q, coenzyme Q10, other ubiquinones, and vitamin E.
  46. GC45324 2,5-dimethyl Celecoxib  
  47. GC49362 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline A food-derived carcinogen
  48. GC40675 2-deoxy-Artemisinin 2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin.
  49. GC15084 2-Methoxyestradiol (2-MeOE2) Apoptotic, antiproliferative and antiangiogenic agent
  50. GC42161 2H-Cho-Arg (trifluoroacetate salt) 2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.
  51. GC40618 3',4',7-Trihydroxyisoflavone 3',4',7-Trihydroxyisoflavone is a natural isoflavonoid that has antioxidant activity.

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