Cell Cycle/Checkpoint(细胞周期/检查点)
Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more
Products for Cell Cycle/Checkpoint
- ATM/ATR(29)
 - Aurora Kinase(57)
 - Cdc42(4)
 - Cdc7(3)
 - Chk(13)
 - c-Myc(27)
 - CRM1(8)
 - Cyclin-Dependent Kinases(69)
 - E1 enzyme(1)
 - G-quadruplex(12)
 - Haspin(5)
 - HMTase(1)
 - Kinesin(27)
 - Ksp(4)
 - Microtubule/Tubulin(248)
 - Mps1(13)
 - Mitotic(7)
 - RAD51(13)
 - ROCK(69)
 - Rho(13)
 - PERK(11)
 - PLK(42)
 - PTEN(6)
 - Wee1(8)
 - PAK(24)
 - Arp2/3 Complex(8)
 - Dynamin(14)
 - ECM & Adhesion Molecules(52)
 - Cytoskeleton & Motor Proteins(63)
 - Endomembrane System & Vesicular Trafficking(35)
 - G1(48)
 - Genotoxic Stress(22)
 - G2/M(35)
 - G2/S(16)
 - Inositol Phosphates(67)
 - Proteolysis(179)
 - Cellular Chaperones(14)
 - Cyclin G-associated Kinase (GAK)(1)
 - MARK(3)
 - NEKs(1)
 
- Cat.No. 产品名称 Information
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                     GC42719 
					
						
							Ac-WEAD-pNA (trifluoroacetate salt)							
                                                           
Ac-Trp-Glu-Ala-Asp-pNA, Ac-Trp-Glu-Ala-Asp-p-nitroanilide, Caspase-1 and Caspase-4 Chromogenic Substrate
A colorimetric caspase-1 and caspase-4 substrate
 
				 - 
                    
                     GC42718 
					
						
							Ac-VEID-CHO (trifluoroacetate salt)							
                                                           
Ac-Val-Glu-Ile-Asp-CHO
A caspase-6 inhibitor
 
				 - 
                    
                     GC42716 
					
						
							Ac-VDVAD-pNA (trifluoroacetate salt)							
                                                           
Ac-Val-Asp-Val-Ala-Asp-pNA, Caspase-2 Chromogenic Substrate, acetyl-Val-Asp-Val-Ala-Asp-p-nitroanilide, acetyl-VDVAD-p-nitroanilide
A colorimetric caspase-2 substrate
 
				 - 
                    
                     GC42715 
					
						
							Ac-VDVAD-CHO (trifluoroacetate salt)							
                                                           
Ac-Val-Asp-Val-Ala-Asp-CHO
A caspase-2, caspase-3, and caspase-7 inhibitor
 
				 - 
                    
                     GC42709 
					
						
							Ac-LEVD-CHO (trifluoroacetate salt)							
                                                           
Ac-Leu-Glu-Val-Asp-CHO, Caspase-4 Inhibitor I
A caspase-4 inhibitor
 
				 - 
                    
                     GC42708 
					
						
							Ac-LEHD-AFC (trifluoroacetate salt)							
                                                           
N-Acetyl-Leu-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin, Caspase-9 substrate (Fluorogenic)
A caspase-4, -5, and -9 fluorogenic substrate
 
				 - 
                    
                     GC42706 
					
						
							Ac-IEPD-AMC (trifluoroacetate salt)							
                                                           
Acetyl-Ile-Glu-Pro-Asp-7-amino-4-Methylcoumarin, Ac-Ile-Glu-Pro-Asp-AMC
A fluorogenic substrate for granzyme B
 
				 - 
                    
                     GC42701 
					
						
							Acetyl Tetrapeptide-3							
                                                           
乙酰基四肽-3
A biomimetic peptide
 
				 - 
                    
                     GC42689 
					
						
							Ac-DNLD-AMC							
                                                           
Ac-Asp-Asn-Leu-Asp-MCA, N-Acetyl-Asp-Asn-Leu-Asp-7-amido-Methylcoumarin, Caspase-3 Substrate
A fluorogenic caspase-3 substrate
 
				 - 
                    
                     GC42688 
					
						
							Ac-DMQD-CHO (trifluoroacetate salt)							
                                                           
Ac-Asp-Met-Gln-Asp-CHO, Caspase-3 Inhibitor
An inhibitor of caspase-3
 
				 - 
                    
                     GC42687 
					
						
							Ac-DMQD-AMC (trifluoroacetate salt)							
                                                           
Ac-Asp-Met-Gln-Asp-AMC, Ac-Asp-Met-Gln-Asp-7-amino-4-methylcoumarin
A fluorogenic substrate for caspase-3
 
				 - 
                    
                     GC42684 
					
						
							Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt)							
                            									            
                    
A sensitive substrate for proteinase 3
 
				 - 
                    
                     GC42683 
					
						
							Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp							
                            									            
                    A sensitive substrate for neutrophil elastase           
					
					 
 
				 - 
                    
                     GC42665 
					
						
							AAF-CMK (trifluoroacetate salt)							
                                                           
NAlaAlaPheCMK, Tripeptidyl Peptidase Inhibitor II
An inhibitor of TPPII
 
				 - 
                    
                     GC42616 
					
						
							7-oxo Staurosporine							
                                                           
BMY 41950, RK-1409
An antibiotic with diverse biological activities
 
				 - 
                    
                     GC42610 
					
						
							7-hydroxy Pestalotin							
                                                           
LL-P880β
A fungal metabolite
 
				 - 
                    
                     GC42586 
					
						
							6α-hydroxy Paclitaxel							
                                                           
6-羟基泰素
A metabolite of paclitaxel
 
				 - 
                    
                     GC42548 
					
						
							5-hydroxy Saxagliptin (hydrochloride)							
                            									            
                    A major active metabolite of saxagliptin           
					
					 
 
				 - 
                    
                     GC42449 
					
						
							4-Methylumbelliferyl-α-L-Iduronide (free acid)							
                                                           
ALPHA-L-四羟基环氧戊酸-4-甲基伞形酯
A fluorogenic substrate for α-L-iduronidase
 
				 - 
                    
                     GC42239 
					
						
							3,6-diacetoxy Phthalonitrile							
                                                           
1,4-二乙酰基-2,3-二氰苯
A fluorescent pH probe
 
				 - 
                    
                     GC42161 
					
						
							2H-Cho-Arg (trifluoroacetate salt)							
                            									            
                    A steroid-based cationic lipid           
					
					 
 
				 - 
                    
                     GC42151 
					
						
							2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)							
                                                           
dGMP
A natural precursor of dGTP
 
				 - 
                    
                     GC41823 
					
						
							1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)							
                                                           
biotin-cap-DPPE
A biotinylated phospholipid
 
				 - 
                    
                     GC41742 
					
						
							(Z-IETD)2-Rh 110 (trifluoroacetate salt)							
                                                           
(Z-Ile-Glu-Thr-Asp)2-R110, Rhodamine 110 bis-(N-CBZ-IETD)2
A fluorogenic substrate for caspase-8
 
				 - 
                    
                     GC41739 
					
						
							(S)-nitro-Blebbistatin							
                                                           
S(-)7Desmethyl8nitro Blebbistatin
A more stable form of (–)-blebbistatin
 
				 - 
                    
                     GC41737 
					
						
							(S)-Glycyl-H-1152 (hydrochloride)							
                                                           
Rho Kinase Inhibitor IV
A ROCK inhibitor
 
				 - 
                    
                     GC41719 
					
						
							(R)-nitro-Blebbistatin							
                                                           
R(-)7Desmethyl8nitro Blebbistatin
A more stable form of (+)-blebbistatin
 
				 - 
                    
                     GC41701 
					
						
							(E)-2-Hexadecenal Alkyne							
                            									            
                    A click chemistry probe for a sphingolipid degradation product           
					
					 
 
				 - 
                    
                     GC41698 
					
						
							(D)2-Rh 110 (trifluoroacetate salt)							
                                                           
D2R, (Asp)2-Rhodamine 110, Rhodamine 110 bis-(L-aspartic acid amide)
A fluorogenic caspase substrate
 
				 - 
                    
                     GC41684 
					
						
							(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane							
                                                           
BMC, Vectrase P
A compound used in protein purification
 
				 - 
                    
                     GC41676 
					
						
							(±)-Nornicotine							
                                                           
3-(吡咯烷-2-基)吡啶
An active metabolite of nicotine and nAChR agonist
 
				 - 
                    
                     GC41656 
					
						
							(±)2-(14,15-Epoxyeicosatrienoyl) Glycerol							
                                                           
(±)214,15EG
A cytochrome P450 metabolite of 2-AG
 
				 - 
                    
                     GC41645 
					
						
							Jacaric Acid							
                                                           
8(Z),10(E),12(Z)-Octadecatrienoic Acid
A conjugated PUFA
 
				 - 
                    
                     GC41564 
					
						
							MPT0B014							
                            									            
                    An inhibitor of tubulin polymerization           
					
					 
 
				 - 
                    
                     GC41563 
					
						
							Globosuxanthone A							
                            									            
                    A fungal metabolite           
					
					 
 
				 - 
                    
                     GC41557 
					
						
							(S)-3'-amino Blebbistatin							
                                                           
(-)-3'-amino Blebbistatin, m-amino Blebbistatin, meta-amino Blebbistatin
A more stable form of (–)-blebbistatin
 
				 - 
                    
                     GC41520 
					
						
							Lachnone A							
                            									            
                    A fungal metabolite           
					
					 
 
				 - 
                    
                     GC41484 
					
						
							(S)-3'-hydroxy Blebbistatin							
                                                           
(-)-3'-hydroxy Blebbistatin, meta-hydroxy-Blebbistatin, m-hydroxy-Blebbistatin
A more stable form of (–)-blebbistatin
 
				 - 
                    
                     GC41443 
					
						
							TAN 1364B							
                                                           
RK-682 (rac-1)
A PTP inhibitor
 
				 - 
                    
                     GC41423 
					
						
							5-trans Prostaglandin E2							
                                                           
transDinoprostone, 5,6trans PGE2
An impurity in commercial lots of PGE1
 
				 - 
                    
                     GC41317 
					
						
							CAY10625							
                            									            
                    An inhibitor of survivin - Smac/DIABLO interaction           
					
					 
 
				 - 
                    
                     GC41305 
					
						
							DA-3003-2							
                                                           
NSC 663285
A Cdc25 phosphatase inhibitor
 
				 - 
                    
                     GC41304 
					
						
							Deoxybrevianamide E							
                            									            
                    A fungal metabolite           
					
					 
 
				 - 
                    
                     GC41272 
					
						
							Lateropyrone							
                                                           
Avenacein Y
A fungal metabolite
 
				 - 
                    
                     GC41268 
					
						
							(E)-2-Hexadecenal							
                                                           
trans-2-Hexadecenal
A long-chain fatty aldehyde
 
				 - 
                    
                     GC41258 
					
						
							Spiroxamine							
                                                           
螺噁茂胺
A fungicide
 
				 - 
                    
                     GC41253 
					
						
							CAY10554							
                                                           
BML259
A potent inhibitor of Cdk5 and Cdk2
 
				 - 
                    
                     GC41242 
					
						
							Acridine Orange							
                                                           
吖啶橙,NSC 194350
Acridine Orange是一种可穿透细胞的核酸选择性荧光染料, Acridine Orange可与DNA或RNA结合时产生荧光,与双链DNA结合时产生绿色荧光(激发光为488nm;发射光为530nm绿色荧光)。
 
				 - 
                    
                     GC41186 
					
						
							Malformin C							
                                                           
畸形素C
A natural bicyclic pentapeptide
 
				 - 
                    
                     GC41156 
					
						
							5-Octyl D-glutamate							
                                                           
5-Octyl ester D-glutamatic acid
A cell-permeable form of D-glutamate