Cell Cycle/Checkpoint(细胞周期/检查点)

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for Cell Cycle/Checkpoint

Cat.No. 产品名称 Information
GC43510 D-myo-Inositol-1,2,4,5-tetraphosphate (sodium salt)
Ins(1,2,4,5)P4, 1,2,4,5IP4
A synthetic, pure inositol phosphate for signal transduction research
GC43509 D-myo-Inositol-1,2,4,5,6-pentaphosphate (sodium salt)
Ins(1,2,4,5,6)P5 (sodium salt), 1,2,4,5,6IP5 (sodium salt)
Pure, synthetic inositol polyphosphate
GC43507 D-myo-Inositol-1,2,3,5-tetraphosphate (sodium salt)
Ins(1,2,3,5)P4 (sodium salt), 1,2,3,5IP4 (sodium salt)
A synthetic, pure inositol phosphate for signal transduction research
GC43506 D-myo-Inositol-1,2,3,5,6-pentaphosphate (sodium salt)
Ins(1,2,3,5,6)-P5, 1,2,3,5,6-IP5
An inositol phosphate
GC43472 Dios-Arg (trifluoroacetate salt) A steroid-based cationic lipid
GC43469 Diminutol
NG72
An NQO1 inhibitor
GC43467 Dimethyldioctadecylammonium (bromide)
双十八烷基二甲基溴化铵
A cationic amphipathic lipid
GC43461 Dihydrocytochalasin B
二氢细胞松弛素 B
An inhibitor of actin assembly and cytokinesis
GC43385 DC-Chol (hydrochloride)
O-[(N,N-二甲基氨基乙基)-氨基甲酰基]胆固醇盐酸盐,?Cholesteryl 3β-N-(dimethylaminoethyl)carbamate
对于DC -Chol（盐酸盐），Aβ；在 Aβ40 (30 µM) 与低浓度 DC-Chol（盐酸盐）(50 ng/mL) 共孵育的图像中观察到纤维。
GC43379 Darinaparsin
Dimethylarsinic glutathione
Darinaparsin是一种新型有机砷化合物，对HL-60、Jurkat及HepG2、A549的IC₅₀为0.5–3.0µM，目前用于复发/难治性淋巴瘤及实体瘤的临床前与临床研究。
GC43371 Dabigatran Acyl-β-D-Glucuronide
达比加群酰基Β维葡糖苷酸
A major active metabolite of dabigatran
GC43370 Dabcyl-RGVVNASSRLA-EDANS (trifluoroacetate salt)
Fluorogenic Human CMV Protease Substrate
A fluorogenic substrate for HCMV protease
GC43369 Dabcyl-GABA-RPKPVE-Nva-WR-Glu(EDANS)-AK-NH2 (trifluoroacetate salt) A fluorogenic substrate for MMP-3
GC43361 Cytostatin (sodium salt) A selective PP2A inhibitor
GC43360 Cytostatin
磷酸己烷雌酚
A selective PP2A inhibitor
GC43354 Cysmethynil
Icmt Inhibitor
An inhibitor of protein prenylation
GC43351 Cylindrospermopsin
柱孢藻毒素
A cyanotoxin
GC43346 Cyclopamine-KAAD
3-酮-N-氨基乙基-N'-氨基己酰二氢肉桂酰环杷明,Cyclopamine-KAAD
A potent inhibitor of hedgehog signaling
GC43321 CPTH6 (hydrobromide) A Gcn5 and pCAF HAT inhibitor
GC43315 Corynecin IV A chloramphenicol-like bacterial metabolite
GC43307 Concanamycin B
刀豆素B
A potent and selective inhibitor of V-ATPases
GC43300 Combretastatin A1
康普瑞汀A-1
An inhibitor of microtubule assembly
GC43286 CMPD101 CMPD101是一种高效、高选择性且具有膜通透性的小分子G蛋白偶联受体激酶2（GRK2）和GRK3抑制剂，其对GRK2和GRK3的IC₅₀值分别为18nM和5.4nM。
GC43265 Chromomycin A2
色霉素A2
An antibacterial and anticancer aureolic acid
GC43250 Cho-Arg (trifluoroacetate salt) A steroid-based cationic lipid
GC43239 Chk2 Inhibitor
SC-203885
A Chk2 inhibitor
GC43230 Ceramides (non-hydroxy) Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires the coordinated action of serine palmitoyl transferase and ceramide synthase.
GC43229 Ceramide Phosphoethanolamines (bovine) Ceramide phosphoethanolamine (CPE) is an analog of sphingomyelin that contains ethanolamine rather than choline as the head group.
GC43219 Cdk2 Inhibitor II
Cyclin-dependent kinase 2 Inhibitor II, SC-221409
Selective and potent inhibitor of Cdk2
GC43217 CDK/CRK Inhibitor
Cdk7 Inhibitor IV, Cyclin-dependent kinase 7 Inhibitor IV, Cyclin-dependent kinase/CDK-related kinase Inhibitor, RGB-286147
A CDK/CRK-specific kinase inhibitor
GC43206 CAY10732
CAY10732是一种检测一氧化碳的荧光探针。
GC43184 CAY10622 A ROCK1 and ROCK2 inhibitor
GC43154 CAY10443
(S)Indan1yl 3,4dichlorobenzylcarbamate
A cytochrome c-dependent inducer of apoptosis
GC43150 CAY10406 A trifluoromethyl analog of a selective caspase inhibitor
GC43146 Caspase-9 Inhibitor III (trifluoroacetate salt)
Ac-LEHD-CMK
A caspase-9 inhibitor
GC43144 Carfilzomib Impurity 13 (hydrochloride) A potential impurity found in commercial carfilzomib preparations
GC43139 Capsanthin (>98%)
辣椒红
A carotenoid with diverse biological activities
GC43135 Cambendazol
坎苯达唑
An anthelmintic agent
GC42997 Butyrolactone I
丁酸内酯I,Olomoucin
Butyrolactone I是具有口服活性的由A. terreus产生的细胞周期蛋白依赖性激酶1（CDK1）的ATP竞争性抑制剂（在PC-14细胞中对cdc2 激酶的IC₅₀值为20μg/ml）。
GC42969 bpV(phen) (potassium hydrate)
Bisperoxovanadium(phen), Potassium Bisperoxo(1,10phenanthroline) oxovanadate (V)
An inhibitor of phosphatases
GC42961 BODIPY 558/568 C12
Red C12
BODIPY 558/568 C12 是一种用于标记脂滴的脂肪酸偶联荧光探针。
GC42960 BODIPY 505/515
4,4-二氟-1,3,5,7-四甲基-4-硼-3A,4A-二氮杂-S-茚烯

BODIPY 505/515是一种亲脂性荧光染料，发出的荧光被广泛用于标记脂质滴（激发/发射：505/515纳米）。
GC42959 BODIPY 493/503
4,4-二氟-1,3,5,7,8-五甲基-4-硼-3A,4A-二氮杂-S-茚烯,Pyrromethene 546; BDP 493/503 lipid stain

BODIPY 493/503是一种亲脂性荧光染料，发出明亮的绿色荧光，被广泛用于标记脂质滴（激发/发射：493/503纳米）。
GC42942 bis-ANS (potassium salt)
4,4'-二苯胺基-1,1'-联萘-5,5'-二磺酸二钾盐,4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic Acid

一种高亲和力非共价外源荧光染料
GC42936 Biotin Tripeptide-1
生物素酰基甘氨酰组氨酰赖氨酸
An ECM peptide conjugated to biotin
GC42933 Binucleine 2 An inhibitor of Drosophila Aurora B kinase
GC42897 BAY 61-3606 (hydrochloride)
A Syk inhibitor
GC42788 Aminopeptidase N Inhibitor Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM).
GC42747 Afuresertib (hydrochloride)
GSK2110183 hydrochloride
A pan-Akt inhibitor
GC42721 Ac-YVAD-CMK
Caspase-1 Inhibitor II
Ac-YVAD-CMK 是一种选择性不可逆的 caspase-1 抑制剂 (Ki=0.8nM)，可阻止促炎细胞因子 IL-1β 的激活。