Search Site
  • 0
    My Cart

    Click Here to Find How Many Items You Have Added:)

qq在线咨询
Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC30904 Molindone hydrochloride (EN-1733A)

    EN-1733A

     A dopamine receptor antagonist
  3. GC30902 Dimenhydrinate

    乘晕宁

     Dimenhydrinate is an over-the-counter drug used to prevent nausea, vomiting, and dizziness caused by motion sickness.
  4. GC30901 Scopolamine N-oxide hydrobromide (Hyoscine N-oxide hydrobromide)

    东莨菪碱N-氧化物氢溴酸盐一水合物

    Scopolamine N-Oxide (Hyoscine N-oxide, Genoscopolamine) is a muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors.
  5. GC30898 6-Methylflavone

    6-甲基黄酮

     6-methylflavone是α1β2γ2L和α1β2GABAA受体的激活剂。
  6. GC30892 Glutaminyl Cyclase Inhibitor 1 GlutaminylCyclaseInhibitor1是谷氨酰胺酰基环化酶(glutaminylcyclase)抑制剂，IC50值为0.5μM。
  7. GC30889 (-)-Securinine

    一叶秋碱

     An alkaloid
  8. GC30888 8-OH-DPAT (8-Hydroxy-DPAT)

    8-Hydroxy-DPAT

    8-OH-DPAT 是5-HT1A 激动剂， pIC50 值为 8.19 ，此外8-OH-DPAT对5-HT1B(pIC50 , 5.42)和5-HT (pIC50 <5)受体亲和力都很弱 。
  9. GC30884 LX2343 An inhibitor of BACE1 and PI3K
  10. GC30880 LP-211 An agonist of 5-HT7 receptors
  11. GC30876 PF-06751979 PF-06751979是一种有效的，脑渗透性的β-淀粉样前体蛋白裂解酶1(BACE1)抑制剂，IC50为7.3nM。
  12. GC30871 Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride)

    6-羟基多巴胺盐酸盐; 6-Hydroxydopamine hydrochloride; 6-OHDA hydrochloride

     Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride)（6-OHDA）是神经递质多巴胺的拮抗剂。
  13. GC30870 Nialamide

    烟肼酰胺

    Nialamide是一种非选择性的,不可逆的单胺氧化酶抑制剂(MAOI),用作抗抑郁药。
  14. GC30866 Anabasine ((S)-Anabasine)

    (+)-假木贼碱; (S)-Anabasine; (+)-Anabasine

     Anabasine ((S)-Anabasine) ((S)-Anabasine ((S)-Anabasine)) 是一种生物碱，在烟草 (Nicotiana) 中是一种微量成分。
  15. GC30865 TPA 023 TPA023是GABAAα2/α3的选择性的激动剂，Ki值为0.19-0.41nM。
  16. GC30862 L-Cycloserine ((S)-4-Amino-3-isoxazolidone)

    环丝氨酸,(S)-Cycloserine; (S)-4-Amino-3-isoxazolidone

     An inhibitor of sphingolipid synthesis and aminotransferases
  17. GC30861 Pavinetant (MLE-4901)

    MLE-4901; AZD2624; AZD4901

     An NK3 receptor antagonist
  18. GC30860 Neu2000

    Salfaprodil free base; Neu2000

     Neu2000 (Salfaprodil free base) 是 N-甲基-D-天冬氨酸 (NMDA) 的 NR2B 选择性和非竞争性拮抗剂。
  19. GC30859 AC260584 AC260584是M1毒蕈碱受体变构激动剂，pEC50值为7.6。
  20. GC30856 Protriptyline hydrochloride

    盐酸普罗替林

    A tricyclic antidepressant
  21. GC30854 Pridopidine (ACR16)

    4-[3-(甲磺酰基)苯基]-1-丙基哌啶,ACR16; ASP2314; FR310826

     Pridopidine (ACR16, ASP2314, FR310826) , a dopamine (DA) stabilizer, acts as an antagonist against sigma 1 receptor (S1R) and dopamine D2 receptor (D2R).
  22. GC30852 Org-26576 Org26576是AMPA受体的正变构调节剂。
  23. GC30849 DREADD agonist 21 A muscarinic hM3Dq DREADD agonist
  24. GC30848 (+)-PD 128907 hydrochloride

    (+)-PD128907,盐酸盐

    A potent D3 receptor agonist
  25. GC30847 IC87201 An inhibitor of the nNOS-PSD-95 protein-protein interaction
  26. GC30844 Afloqualone

    氟喹酮; HQ-495

     An Analytical Reference Standard
  27. GC30840 Quinagolide hydrochloride (CV205-502 hydrochloride)

    盐酸喹高利特; CV205-502 hydrochloride

    Quinagolide hydrochloride (CV205-502 hydrochloride) 是一种选择性多巴胺 D2 受体激动剂，也是一种催乳素抑制剂。
  28. GC30839 Traxoprodil

    曲索罗地

    An antagonist of NR2B subunit-containing NMDA receptors
  29. GC30836 MK-7622 (M1 receptor modulator)

    3-[(1S,2S)-2-羟基环己基]-6-[(6-甲基-3-吡啶基)甲基]苯并[H]喹唑啉-4(3H)-酮,M1 receptor modulator

     A positive allosteric modulator of M1 mAChRs
  30. GC30835 Rislenemdaz (MK-0657)

    MK-0657; CERC-301

    Rislenemdaz (MK-0657) (CERC-301) 是一种口服生物可利用的选择性 N-甲基-D-天冬氨酸 (NMDA) 受体亚基 2B (GluN2B) 拮抗剂，其 Ki 和 IC 50 分别为 8.1 nM 和 3.6 nM。
  31. GC30827 Pipequaline (PK-8165)

    哌夸林,PK-8165

     A partial agonist of central benzodiazepine receptors
  32. GC30826 Temanogrel (APD791)

    APD791

     Temanogrel (APD791) 是一种高度选择性的 5-HT2A 受体拮抗剂，Ki 为 4.9 nM。
  33. GC30824 Veralipride ((±)-Veralipride)

    维拉必利,(±)-Veralipride; LIR166

    Veralipride ((±)-Veralipride) 是一种 D2 受体拮抗剂。
  34. GC30823 Edonerpic maleate (T-817 maleate)

    1-(3-(2-(苯并[B]噻吩-5-基)乙氧基)丙基)氮杂环丁烷-3-醇马来酸,T-817 maleate; T-817MA

     T-817MA propyl}-3-azetidinol maleate] 是一种新合成的阿尔茨海默病 (AD) 治疗剂，具有神经保护作用β-淀粉样肽 (Aβ) 的毒性和促进神经突生长的作用.T-817MA 预处理 24 小时后，T-817MA 在 0.1 和 1 uM 时显着防止 H2O2 处理引起的神经元损伤。
  35. GC30822 Solifenacin (YM905)

    索利那新; YM905 free base

    Solifenacin (YM905) is a competitive muscarinic receptor antagonist. The binding of acetylcholine to these receptors, particularly the M3 receptor subtype, plays a critical role in the contraction of smooth muscle.
  36. GC30821 JNJ-39758979 JNJ-39758979是一个有选择性且具有高亲和性的组胺H4受体拮抗剂,其Ki值为12.5nM。
  37. GC30818 ZL006 An nNOS/PSD-95 interaction inhibitor
  38. GC30812 Imidafenacin (KRP-197)

    咪达那新; KRP-197; ONO-8025

     Imidafenacin (KRP-197, ONO-8025) is a urinary antispasmodic of the anticholinergic class. It is a novel antimuscarinic agent with safety and efficacy, has been clinically used for the treatment of overactive bladder. Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors(IC50=4.13 nM). IC50 value: 0.3 nM(M3).
  39. GC30810 Donepezil (E2020)

    多奈哌齐; E2020 free base

     Donepezil (E2020)是一种乙酰胆碱酯酶（AChE）抑制剂，IC50为6.7nM。
  40. GC30809 VU0467154

    5-氨基-3,4-二甲基-噻吩并[2,3-C]哒嗪-6-羧酸4-三氟甲磺酰基-苄基酰胺

     A positive allosteric modulator of the M4 muscarinic acetylcholine receptor
  41. GC30807 ZSET1446 (ST-101)

    ST-101

     ZSET1446 (ST-101) 是一种新型认知增强剂，可显着改善各种类型的阿尔茨海默病 (AD) 模型中的学习缺陷。
  42. GC30797 lumateperone Tosylate (ITI-007)

    1-(4-氟苯基)-4-[(6BR,10AS)-2,3,6B,9,10,10A-六氢-3-甲基-1H-吡啶并[3',4':4,5]吡咯并[1,2,3-DE]喹喔啉-8(7H)-基]-1-丁酮对甲苯磺酸盐,ITI-007 tosylate

    An atypical antipsychotic
  43. GC30796 Nelotanserin (APD125)

    1-[3-(4-溴-1-甲基-1H-吡唑-5-基)-4-甲氧基苯基]-3-(2,4-二氟苯基)脲,APD125

     Nelotanserin (APD125) 是一种有效的 5-HT2A 反向激动剂、中度有效的 5-HT2C 部分反向激动剂和弱 5-HT2B 反向激动剂，在 IP 积累试验中 IC50 分别为 1.7、79、791 nM。
  44. GC30790 Triflupromazine hydrochloride

    盐酸三氟丙嗪

     A phenothiazine with diverse biological activities
  45. GC30788 L-Glutamic acid monosodium salt (Monosodium glutamate)

    谷氨酸单钠盐

     L-Glutamic acid monosodium salt is the sodium salt of glutamic acid, found naturally in tomatoes, cheese and other foods. L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
  46. GC30787 Sertindole (Lu 23-174)

    舍吲哚; Lu 23-174

     An atypical antipsychotic
  47. GC30780 Fipexide

    非哌西特

     Fipexide (hydrochloride) is a psychoactive drug of the piperazine class.
  48. GC30775 Histamine (Ergamine)

    组胺; Ergamine

    A biogenic amine
  49. GC30774 Tat-NR2B9c

    Tat-NR2Bct; NA-1

     Tat-NR2B9c 旨在通过阻止突触后密度蛋白 95 (PSD-95) 与 N-甲基-D-天冬氨酸 (NMDA) 受体和神经元一氧化氮结合来阻止一氧化氮 (NO) 的产生氧化物合成酶。
  50. GC30773 Phenelzine sulfate

    硫酸苯乙肼

     An inhibitor of MAO
  51. GC30772 Dopamine serotonin antagonist-1

    氯氮平杂质,Deschloroclozapine

     Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.

Items 2701 to 2750 of 3961 total

per page
  2. 53
  3. 54
  4. 55
  5. 56
  6. 57

Set Descending Direction