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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC46781 Acetaminophen-d4

    对乙酰氨基酚 d4

     An internal standard for the quantification of acetaminophen
  3. GC46778 Acamprosate-d3 (calcium salt)

    N-acetyl Homotaurinate-d3, N-acetyl Homotaurine-d3

     An internal standard for the quantification of acamprosate
  4. GC46753 9(S),12(S),13(S)-TriHOME

    (-)-Pinellic Acid, 9S,12S,13S-Pinellic Acid

     An oxylipin
  5. GC46720 6,9-Dichloro-1,2,3,4-tetrahydroacridine

    NSC 1227

     A synthetic intermediate in the synthesis of AChE inhibitors
  6. GC46715 5α,6β-Dihydroxycholestanol-d7

    Cholestanetriol-d7, 5α,6β-di-OHC-d7

     An internal standard for the quantification of 5α,6β-dihydroxycholestanol
  7. GC46706 5-Methyltetrahydrofolic Acid (hydrate)

    5-methyl THF, Prefolic A

     叶酸的生物活性形式
  8. GC46675 4-Phenyl-2-pyrrolidinone

    4-苯基-2-吡咯烷酮

     A precursor and synthetic intermediate
  9. GC46583 3-Amino-2,6-Piperidinedione

    3-氨基-2,6-哌啶二酮

     An active metabolite of (±)-thalidomide
  10. GC46557 3,4-Dihydroquinolin-2(1H)-one

    3,4-二氢-2(1H)-喹啉酮

     A building block
  11. GC46505 2-(Isopentylamino)naphthalene-1,4-dione A vitamin K analog
  12. GC46478 1a-monohomo-17-phenyl trinor Prostaglandin F2α

    1a-monohomo-17-phenyl trinor PGF2α

     A neuropeptide with diverse biological activities
  13. GC46466 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α

    17trifluoromethylphenyl13,14dihydro trinor PGF2α

     A prostaglandin F derivative similar to latanoprost free acid
  14. GC46463 17-phenyl trinor Prostaglandin F2α-d4

    Bimatoprost (free acid)d4, 17phenyl trinor PGF2αd4

     An internal standard for the quantification of bimatoprost (free acid)
  15. GC46462 17-phenyl trinor Prostaglandin F2α isopropyl amide

    17-phenyl trinor PGF2α isopropyl amide

     A derivative of 17-phenyl trinor PGF2α ethyl amide
  16. GC46461 17-phenyl trinor Prostaglandin F2α glycinamide methyl ester

    17-phenyl trinor PGF2α glycinamide methyl ester

     A neuropeptide with diverse biological activities
  17. GC46460 17-phenyl trinor Prostaglandin F2α glycinamide

    17-phenyl trinor PGF2α glycinamide

     A neuropeptide with diverse biological activities
  18. GC46459 17-phenyl trinor Prostaglandin F2α ethyl amide-d4

    Bimatoprost-d4, 15(S)-Bimatoprost-d4, 17-phenyl trinor PGF2α ethyl amide-d4

     A neuropeptide with diverse biological activities
  19. GC46458 17-phenyl trinor Prostaglandin F2α dimethyl amide

    17-phenyl trinor PGF2α dimethyl amide, Bimatoprost dimethyl amide

     An isomer of 17-phenyl trinor prostaglandin F2α ethyl amide
  20. GC46451 16F16 A PDI inhibitor
  21. GC46437 14-dehydro Zymostenol

    Δ8,14-Cholestandienol, Cholesta-8,14-dien-3β-ol

     A cholesterol precursor
  22. GC46413 11β-Prostaglandin F2α-d9

    9α,11β-PGF2α-d9, 11β-PGF2α-d9, 11-epi PGF2α-d9

     A neuropeptide with diverse biological activities
  23. GC46412 11β-Prostaglandin F2α-d4

    9α,11βPGF2αd4, 11βPGF2αd4, 11epi PGF2αd4

     An internal standard for the quantification of 11β-PGF F2α
  24. GC46366 1,2,3,4-Tetrahydro-β-carboline

    1,2,3,4-四氢-9H-吡啶[3,4-B]并吲哚

     A serotonin reuptake inhibitor and metabolite of tryptamine
  25. GC46362 [Sar9, Met(O2)11]-Substance P (trifluoroacetate salt)

    Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-{Sar}-Leu-MetO2-NH2

     A neuropeptide with diverse biological activities
  26. GC46355 (S)-Pramipexole-d5 (hydrochloride)

    普拉克索杂质

     An internal standard for the quantification of (S)-pramipexole
  27. GC46352 (S)-DO271 An inactive control for DO264
  28. GC46346 (S)-(+)-Clopidogrel-d3 (sulfate) A neuropeptide with diverse biological activities
  29. GC46339 (R)-4-Amino-3-hydroxybutyric Acid

    (R)-(-)-4-氨基-3-羟基丁酸

     A GABA receptor modulator
  30. GC46305 (±)-Nicotine-d3

    (+/-)-氘代甲基-烟碱(甲基-2-(3-吡啶基)吡咯烷丝氨酸BETA-羟基丙氨酸)

     An internal standard for the quantification of (±)-nicotine
  31. GC46290 (±)-Ibuprofen-d3

    氘代布洛芬,(±)-Ibuprofen-d3

     An Analytical Reference Standard
  32. GC46288 (±)-Epibatidine (hydrochloride)

    CMI 545 dihydrochloride

     An agonist of α4β2 subunit-containing nAChRs
  33. GC46274 (±)-Baclofen-d4

    巴氯芬 d4

     An internal standard for the quantification of (±)-baclofen
  34. GC46272 (±)-Asenapine-13C-d3 (hydrochloride) An internal standard for the quantification of (±)-asenapine
  35. GC46248 (-)-Ropivacaine-d7 (hydrochloride)

    (S)-Ropivacaine-d7

     An internal standard for the quantification of (–)-ropivacaine
  36. GC46246 (-)-Hyoscyamine-d3

    L-Hyoscyamine-d3, (S)-Hyoscyamine-d3

     A neuropeptide with diverse biological activities
  37. GC19382 Methoctramine (hydrate) A selective muscarinic M2 receptor antagonist
  38. GC61389 Ziprasidone amino acid

    齐拉西酮开环物,氨基酸杂质,Ziprasidone Impurity C; Ziprasidone open ring impurity

     Ziprasidoneaminoacid(ZiprasidoneImpurityC)是Ziprasidone的杂质。Ziprasidone是5-HT和多巴胺(dopaminereceptor)受体拮抗剂，具有抗精神病活性。
  39. GC61387 Zamifenacin

    UK-76654

     A muscarinic M3 receptor antagonist
  40. GC61382 Xanthoangelol

    黄色当归醇

     Xanthoangelol, a chalcone found in the roots of Angelica keiskei, is a nonselective monoamine oxidase (MAO) inhibitor and a potent dopamine β-hydroxylase (DBH) inhibitor. It has anti-inflammatory, antibiotic and pro-apoptotic activities.
  41. GC61378 VU0238441 VU0238441 is a pan muscarinic acetylcholine receptor (mAChR) positive allosteric modulator (PAM) with EC50 of 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and >10 μM for M5, M3, M2, M1 and M4, respectively.
  42. GC61377 VU0119498

    1-(4-溴苄基)吲哚-2,3-二酮

     An M1, M3, and M5 muscarinic receptor positive allosteric modulator
  43. GC61371 Veratric acid

    藜芦酸

     Veratricacid(3,4-Dimethoxybenzoicacid)是从蔬菜和水果中得到的多酚物质，可口服，具有抗氧化、保护心血管和抗炎活性。当细胞受到UVB辐射时，Veratricacid能够减少上调的COX-2表达，降低PGE2和IL-6水平。
  44. GC61367 VAF347 VAF347是一种细胞可渗透且高度亲和力的芳烃受体(AhR)激动剂，可诱导AhR信号传导。VAF347抑制颗粒单核细胞(GM期)前体中CD14+CD11b+单核细胞的发育。VAF347具有抗炎作用。
  45. GC61337 Tolmetin

    托麦汀；托美丁

     Tolmetin (Tolectin) is a nonsteroidal anti-inflammatory drug of the heterocyclic acetic acid derivative class and also exhibits analgesic and antipyretic activity.
  46. GC61317 Tebanicline dihydrochloride

    Ebanicline dihydrochloride; ABT-594 dihydrochloride

     Tebaniclinedihydrochloride(Ebaniclinedihydrochloride)是nAChR的调节物，具有有效的口服止痛活性。抑制cytisine与神经元nAChR的结合的Ki值为37pM。
  47. GC61286 SP-8356 SP-8356, an anti-inflammatory synthetic verbenone derivative, is a CD147 inhibitor with respect to its regulation of breast cancer cell behavior and cancer progression.
  48. GC61281 SKF-83566 A dopamine D1 receptor antagonist
  49. GC61268 SB 243213 A 5-HT2C receptor inverse agonist
  50. GC61256 Rupatadine D4 fumarate

    UR-12592 D4 fumarate

     RupatadineD4fumarate(UR-12592D4fumarate)是Rupatadinefumarate的氘代标记物。RupatadineFumarate(UR-12592Fumarate)富马酸盐是PAF/H1受体双抑制剂，Ki值分别为0.55μM和0.1μM。
  51. GC61255 Rubrofusarin triglucoside

    红镰霉素三葡萄糖苷

     Rubrofusarintriglucoside是一种从决明子种子中分离得到的糖苷化合物，可抑制人单胺氧化酶A(hMAO-A)，IC50为85.5μM。

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