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Cell Cycle/Checkpoint

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for  Cell Cycle/Checkpoint

  1. Cat.No. Product Name Information
  2. GC11593 AZD0156 ATM kinase inhibitor
  3. GC14709 AZD1152 Aurora B kinase inhibitor,highly potent and selective
  4. GC19468 AZD1390

    AZD1390 is a potent and selective ATM inhibitor

  5. GC16941 AZD6738 ATR inhibitor
  6. GC10546 AZD7762 Checkpoint kinase inhibitor,ATP competitive
  7. GC14955 Barasertib (AZD1152-HQPA)

    Aurora Kinase B inhibitor, Potent and selective

  8. GC33420 BAY-1895344 BAY-1895344是一种有效、可口服、选择性的ATR抑制剂,IC50值为7nM。具有抗肿瘤活性。
  9. GC34374 BAY-1895344 hydrochloride BAY-1895344hydrochloride是一种有效、可口服、选择性的ATR抑制剂,IC50值为7nM。具有抗肿瘤活性。
  10. GC19058 BAY1217389 BAY 1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM.
  11. GC32868 BDP5290 BDP5290是ROCK和MRCK的有效抑制剂,对于ROCK1,ROCK2,MRCKα和MRCKβ的IC50值分别为5nM,50nM,10nM和100nM。
  12. GC12450 BI 2536 Plk1 inhibitor,potent and ATP-competitive
  13. GC17828 BI-847325 dual inhibitor of MEK and Aurora kinases
  14. GC11224 BI6727(Volasertib) Plk inhibitor,highly potent
  15. GC11648 BML-277 Chk2 inhibitor,potent and highly selective
  16. GC12865 BMS265246 CDK1/2 inhibitor,potent and selective
  17. GC34102 BNC105 BNC105是一种具有抗增殖和破坏肿瘤血管功能的,微管蛋白聚合抑制剂。
  18. GC14002 Bohemine CDK inhibitor
  19. GC32846 BOS-172722 BOS-172722是单极纺锤体1(MPS1)检查点的抑制剂,其IC50值为2nM。
  20. GC12001 BS-181 CDK7 inhibitor,highly selective
  21. GC13690 BS-181 HCl CDK7 inhibitor,highly selective

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